Výsledky vyhledávání - "Vidya Gadang"

Critical Role for Mixed-Lineage Kinase 3 in Acetaminophen-Induced Hepatotoxicity

Autor: Anja Jaeschke, Vidya Gadang, Manju Sharma

Publikováno v: Molecular Pharmacology. 82:1001-1007

c-Jun NH(2)-terminal kinase (JNK) activation plays a major role in acetaminophen (APAP)-induced hepatotoxicity. However, the exact mechanism of APAP-induced JNK activation is incompletely understood. It has been established that apoptosis signal-regu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41b343d95d9c45239073192ebafa039
https://doi.org/10.1124/mol.112.079863

Zobrazit plný text záznamu

Trans – trans Conjugated Linoleic Acid Enriched Soybean Oil Reduces Fatty Liver and Lowers Serum Cholesterol in Obese Zucker Rats

Autor: Vidya Gadang, Vishal P. Jain, Latha Devareddy, William Gilbert, Andrew Proctor

Publikováno v: Lipids. 46:961-968

Conjugated linoleic acid (CLA) is a collection of octadecadienoic fatty acids that have been shown to possess numerous health benefits. The CLA used in our study was produced by the photoisomerization of soybean oil and consists of about 20% CLA; thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d5af08ee53a37682940eb25792f8fd
https://doi.org/10.1007/s11745-011-3585-6

Zobrazit plný text záznamu

Dietary Supplementation of Fructooligosaccharides Reduces Hepatic Steatosis Associated with Insulin Resistance in Obese Zucker Rats

Autor: Lydia Kaume, William Gilbert, Vidya Gadang, Latha Devareddy

Publikováno v: Functional Foods in Health and Disease, Vol 1, Iss 5 (May), Pp 199-213 (2011)

Background: One in five adults in the United States is obese as defined by a body mass index of 30 kg/m2. Obesity is associated with metabolic syndrome, a combination of medical conditions including cardiovascular disease, type 2 diabetes, hypertensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4941f7a16820e2a37debfd8563e9da47
http://www.functionalfoodscenter.net/files/44278413.pdf

Zobrazit plný text záznamu

Dietary Bitter Melon Seed Increases Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Adipose Tissue, Down-Regulates the Nuclear Factor-κB Expression, and Alleviates the Symptoms Associated with Metabolic Syndrome

Autor: Latha Devareddy, Navam S. Hettiararchchy, Laxmansa C. Katwa, Ronny Horax, Vidya Gadang, William Gilbert

Publikováno v: Journal of Medicinal Food. 14:86-93

The objective of this study was to examine the extent to which bitter melon seed (BMS) alleviates the symptoms associated with metabolic syndrome and elucidate the mechanism by which BMS exerts beneficial effects. Three-month-old female Zucker rats w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b69dddecc0dea56aaa5139bd076864
https://doi.org/10.1089/jmf.2010.0010

Zobrazit plný text záznamu

Mixed-lineage kinase 3 deficiency promotes neointima formation through increased activation of the RhoA pathway in vascular smooth muscle cells

Autor: Vidya Gadang, Eddy S. Konaniah, Anja Jaeschke, David Y. Hui

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 34(7)

Objective— Mitogen-activated protein kinase pathways play an important role in neointima formation secondary to vascular injury, in part by promoting proliferation of vascular smooth muscle cells (VSMC). Mixed-lineage kinase 3 (MLK3) is a mitogen-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8962f4e746ff0ba440b19e510123107f
https://pubmed.ncbi.nlm.nih.gov/24790140

Zobrazit plný text záznamu

MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet

Autor: Vidya Gadang, Anja Jaeschke, David Y. Hui, Andriy Myronovych, Diego Perez-Tilve, Rohit Kohli

Saturated fatty acids activate the c-Jun NH2-terminal kinase (JNK) pathway, resulting in chronic low-grade inflammation and the development of insulin resistance. Mixed-lineage kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAP3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f78966945a4a5adf09e81de53044af5
https://europepmc.org/articles/PMC3891220/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání