Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Vidya G, Kattige"'
Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E
Autor:
Nagarajan, Muthukaman, Macchindra, Tambe, Mahamadhanif, Shaikh, Dnyandeo, Pisal, Sanjay, Deshmukh, Shital, Tondlekar, Neelam, Sarode, Lakshminarayana, Narayana, Jitendra M, Gajera, Vidya G, Kattige, Srinivasa, Honnegowda, Vikas, Karande, Abhay, Kulkarni, Dayanidhi, Behera, Satyawan B, Jadhav, Girish S, Gudi, Neelima, Khairatkar-Joshi, Laxmikant A, Gharat
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(11)
A series of substituted tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives have been synthesized and their mPGES-1 biological activity has been disclosed in detail. Structure-activity relationship (SAR) optimization provided inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9874f5bf5efea64e8794baffe42a441c
https://pubmed.ncbi.nlm.nih.gov/28400234
https://pubmed.ncbi.nlm.nih.gov/28400234
Autor:
Nagarajan, Muthukaman, Sanjay, Deshmukh, Neelam, Sarode, Shital, Tondlekar, Macchindra, Tambe, Dnyandeo, Pisal, Mahamadhanif, Shaikh, Vidya G, Kattige, Srinivasa, Honnegowda, Vikas, Karande, Abhay, Kulkarni, Satyawan B, Jadhav, Mahamad Yunnus A, Mahat, Girish S, Gudi, Neelima, Khairatkar-Joshi, Laxmikant A, Gharat
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(24)
The discovery and SAR of potent, selective dioxane-fused tricyclic benz[d]imidazole derivatives as mPGES-1 inhibitor are herein described. Various amide modifications in this series afforded many potent mPGES-1 inhibitors, of which 17d proved to be s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd13d730eff612038af486251a9056a6
https://pubmed.ncbi.nlm.nih.gov/27865703
https://pubmed.ncbi.nlm.nih.gov/27865703