Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Vidya C. Sinha"'
1
Akademický článek
The cytosolic iron–sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors
Autor: Abena B. Redwood, Xiaomei Zhang, Sahil B. Seth, Zhongqi Ge, Wendy E. Bindeman, Xinhui Zhou, Vidya C. Sinha, Timothy P. Heffernan, Helen Piwnica-Worms
Publikováno v: npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract The relationship between ATR/Chk1 activity and replication stress, coupled with the development of potent and tolerable inhibitors of this pathway, has led to the clinical exploration of ATR and Chk1 inhibitors (ATRi/Chk1i) as anticancer the
Externí odkaz: https://doaj.org/article/f52fc4ae77174e23822274182d58cffc
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2
Akademický článek
Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast
Autor: Vidya C. Sinha, Amanda L. Rinkenbaugh, Mingchu Xu, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Jiansu Shao, Yuan Qi, John A. Zebala, Dean Y. Maeda, Florencia McAllister, Helen Piwnica-Worms
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The classification of breast lesions as indolent or aggressive to tailor treatment is crucial. Here, the authors use single-cell transcriptomics and multiparametric imaging of a breast cancer mouse model, report distinct tumor-immune features for the
Externí odkaz: https://doaj.org/article/edf450673bba4946ad0410cdc2344397
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9
Abstract P3-07-03: Withdrawn
Autor: Jiansu Shao, Helen Piwnica-Worms, Vidya C. Sinha, Xiaomei Zhang, Amanda L. Rinkenbaugh
Publikováno v: Cancer Research. 79:P3-07
This abstract was withdrawn by the authors. Citation Format: Rinkenbaugh AL, Sinha VC, Zhang X, Shao J, Piwnica-Worms H. Withdrawn [abstract]. In: Proceedings of the 2018 San Antonio Breast Cancer Symposium; 2018 Dec 4-8; San Antonio, TX. Philadelphi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b04106a4de4edf5bf243b8a6b77b9578
https://doi.org/10.1158/1538-7445.sabcs18-p3-07-03
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10
Abstract 1595: Analysis of spatiotemporal phenotypic heterogeneity in chemoresistant triple negative breast cancer using imaging mass cytometry
Autor: Amanda L. Rinkenbaugh, Vidya C. Sinha, Pankaj Singh, Yuan Qi, Jiansu Shao, Xiaomei Zhang, Gloria V. Echeverria, W. Fraser Symmans, Stacy L. Moulder, Helen Piwnica-Worms
Publikováno v: Cancer Research. 82:1595-1595
Shifts in tumor cell phenotype in response to selective pressures (i.e. changing microenvironments, drug treatments) pose one of the biggest obstacles to successful breast cancer therapies. Phenotypically diverse breast tumor and stroma subpopulation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb03d5197f07b7e25c16f40fbf616cb3
https://doi.org/10.1158/1538-7445.am2022-1595
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