Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vidya Bhushan Lohray"'
Autor:
Sanjeev Kumar, Shaikh Abdul Rajjak, Manojit Pal, Vidya Bhushan Lohray, Ramesh Mullangi, Koteswar Rao Yeleswarapu, Venugopal Rao Veeramaneni, Parimal Misra, Seshagiri Rao Casturi, Akhila Vangoori
Publikováno v:
Letters in Drug Design & Discovery. 2:329-340
A number of novel 1,5-diarylpyrazoles possessing N-substitution on the sulfonamide (-SO2NH2) moiety were synthesized and tested for COX-1/COX-2 inhibition in vitro. Many of these 1,1-dioxo-2,3- dihydrobenzo(d)isothiazolyl substituted 1,5-diarylpyrazo
Publikováno v:
Pure and Applied Chemistry. 77:179-184
Several substituted α-alkoxy phenyl propionic acids were synthesized, and their hypotriglyceridemic properties were evaluated in Swiss albino mice. Some of the compounds showed excellent triglyceride- and cholesterol-lowering properties even at a do
Publikováno v:
Pure and Applied Chemistry. 77:195-200
A set of substituted piperazinyloxazolidinone derivatives has been studied for their antibacterial activity in a few gram-positive bacteria. The structural modifications have provided a superior compound than linezolid, the only drug of this class in
Publikováno v:
Tetrahedron Letters. 45:6269-6272
Two oxazolidine-2-thiones, thio-analogs of linezolid, were synthesized and their antibacterial properties evaluated. Unlike oxazolidinones, the thio-analogs did not inhibit the growth of Gram positive bacteria. A molecular modeling study has been car
Autor:
Ravi K. Babu, Gurram Ranga Madhavan, Ranjan Chakrabarti, Ramanujam Rajagopalan, Katneni Kasiram, Lohray Braj Bhushan, Javed Iqbal, Parimal Misra, V Balraju, Juluri Suresh, Sunil Kumar, Rao N. V. S. Mamidi, Vidya Bhushan Lohray
Publikováno v:
European Journal of Medicinal Chemistry. 36:627-637
We report here the synthesis of a series of 5-[4-[2-[substituted phthalazinones-2(or 4)yl]ethoxy]phenylmethyl]thiazolidine-2,4-diones and 5-[4-[2-[2,3-benzoxazine-4-one-2-yl]ethoxy]phenylmethyl]thiazolidine-2,4-diones and their plasma glucose and pla
Autor:
Harikishore Pingali, Walter Wahli, Cicerone Tudor, Yves Engelborghs, Laurent Gelman, Jerome N. Feige, Béatrice Desvergne, Vidya Bhushan Lohray
Publikováno v:
The Journal of biological chemistry. 282(7)
The nucleus is an extremely dynamic compartment, and protein mobility represents a key factor in transcriptional regulation. We showed in a previous study that the diffusion of peroxisome proliferator-activated receptors (PPARs), a family of nuclear
Publikováno v:
Drug Discovery and Development: Drug Development, Volume 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec2cd284436e7910bca2f0fcc696eec
https://doi.org/10.1002/9780470085226.ch24
https://doi.org/10.1002/9780470085226.ch24
Publikováno v:
Drug Discovery and Development: Drug Development, Volume 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb8147f5eefc7b275ad13e61c0c35b0
https://doi.org/10.1002/9780470085226.ch19
https://doi.org/10.1002/9780470085226.ch19
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(14)
Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the pr
Autor:
Vidya Bhushan Lohray, Vijay B. Takale, Brijesh Kumar Srivastava, Prashant B. Kapadnis, Braj Bhushan Lohray, Sunil V. Gupta, Manish Solanki, Purvi Pandya
Publikováno v:
ChemInform. 35
A number of substituted piperazinyl oxazolidinone derivatives have been synthesized and their antibacterial activities were evaluated by MIC determination. A systematic SAR was carried out to get highly potent oxazolidinone derivatives.