Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Vidu, Garg"'
Autor:
Kira Mascho, Svetlana A. Yatsenko, Cecilia W. Lo, Xinxiu Xu, Jennifer Johnson, Lindsey R. Helvaty, Stephanie Burns Wechsler, Chaya N. Murali, Seema R. Lalani, Vidu Garg, Jennelle C. Hodge, Kim L. McBride, Stephanie M. Ware, Jiuann-Huey Ivy Lin
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction5p deletion syndrome, also called Cri-du-chat syndrome 5p is a rare genetic syndrome with reports up to 36% of patients are associated with congenital heart defects. We investigated the association between left outflow tract obstruction a
Externí odkaz:
https://doaj.org/article/2ea28b86dde34d79982956d3247450a9
Autor:
Meghan Hanley, Matthew Alonzo, Shiqiao Ye, Yang Yu, Javier Contreras, Jade Hayden, Vidu Garg, Ming-Tao Zhao
Publikováno v:
Stem Cell Research, Vol 80, Iss , Pp 103526- (2024)
Pulmonary atresia with intact ventricular septum (PA/IVS) is a rare congenital heart defect that causes a significant decrease of blood outflow from the heart and is fatal if left untreated. iPSC line NCHi013-A was produced from peripheral blood mono
Externí odkaz:
https://doaj.org/article/22a007014752402dbd30d64d1729f91e
Publikováno v:
Stem Cell Research, Vol 80, Iss , Pp 103530- (2024)
Pulmonary atresia with intact ventricular septum (PA-IVS) is a rare congenital heart defect characterized by underdeveloped pulmonary valve and right ventricular hypoplasia. Neonates undergoing surgery to open pulmonary valve have a range of post-sur
Externí odkaz:
https://doaj.org/article/6e1c311a2d2e43b8ba3fc568570f49ff
Autor:
Jihyun Jang, Mette Bentsen, Ye Jun Kim, Erick Kim, Vidu Garg, Chen-Leng Cai, Mario Looso, Deqiang Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Failure of proper ventricular trabeculation is often associated with congenital heart disease. Support from endocardial cells, including the secretion of extracellular matrix and growth factors is critical for trabeculation. However, it is p
Externí odkaz:
https://doaj.org/article/e8ec9ab3b18a479e8dfee5d6b7180d34
Publikováno v:
Stem Cell Research, Vol 78, Iss , Pp 103457- (2024)
Truncus arteriosus (TA) is a congenital heart defect where one main blood vessel emerges from the heart, instead of individual aorta and pulmonary artreries. Peripheral mononuclear cells (PBMCs) of a male infant with TA were reporogrammed using Senda
Externí odkaz:
https://doaj.org/article/938bb40affa34493b2bd1c2fc07a97b0
Publikováno v:
Stem Cell Research, Vol 74, Iss , Pp 103281- (2024)
NOTCH1 signaling is crucial for cardiovascular development. Numerous studies have identified heterozygous NOTCH1 loss of function and missense variants associated with a spectrum of congenital heart diseases (CHD). We generated induced pluripotent st
Externí odkaz:
https://doaj.org/article/8bcca3e42d90409fa76dbaa88ad6e715
Autor:
Isaac Stanberry, David Cunningham, Shiqiao Ye, Matthew Alonzo, Ming-Tao Zhao, Vidu Garg, Brenda Lilly
Publikováno v:
Stem Cell Research, Vol 72, Iss , Pp 103213- (2023)
Alagille syndrome (ALGS) is a multisystem disease with high variability in clinical features. ALGS is predominantly caused by pathogenic variants in the Notch ligand JAG1. An iPSC line, NCHi011-A, was generated from a ALGS patient with complex cardia
Externí odkaz:
https://doaj.org/article/76446d6f621a40738f84a8d0537f9766
Autor:
Elizabeth E. Blue, Janson J. White, Michael K. Dush, William W. Gordon, Brent H. Wyatt, Peter White, Colby T. Marvin, Emmi Helle, Tiina Ojala, James R. Priest, Mary M. Jenkins, Lynn M. Almli, Jennita Reefhuis, Faith Pangilinan, Lawrence C. Brody, Kim L. McBride, Vidu Garg, Gary M. Shaw, Paul A. Romitti, Wendy N. Nembhard, Marilyn L. Browne, Martha M. Werler, Denise M. Kay, Seema Mital, Jessica X. Chong, Nanette M. Nascone-Yoder, Michael J. Bamshad
Publikováno v:
HGG Advances, Vol 4, Iss 4, Pp 100232- (2023)
Summary: Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect (CHD) characterized by hypoplasia of the left ventricle and aorta along with stenosis or atresia of the aortic and mitral valves. HLHS represents only ∼4%–8% of a
Externí odkaz:
https://doaj.org/article/02c4caf366fb4060935dbf5c314b1e69
Autor:
Benjamin J. Landis, Lindsey R. Helvaty, Gabrielle C. Geddes, Jiuann‐Huey Ivy Lin, Svetlana A. Yatsenko, Cecilia W. Lo, William L. Border, Stephanie Burns Wechsler, Chaya N. Murali, Mahshid S. Azamian, Seema R. Lalani, Robert B. Hinton, Vidu Garg, Kim L. McBride, Jennelle C. Hodge, Stephanie M. Ware
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 18 (2023)
Background Chromosomal microarray analysis (CMA) provides an opportunity to understand genetic causes of congenital heart disease (CHD). The methods for describing cardiac phenotypes in patients with CMA abnormalities have been inconsistent, which ma
Externí odkaz:
https://doaj.org/article/3ce4e66e20b2416085e8144a51318ce2
Autor:
David Cunningham, Isaac Stanberry, Shiqiao Ye, Matthew Alonzo, Ming-Tao Zhao, Vidu Garg, Brenda Lilly
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103177- (2023)
Alagille syndrome (ALGS) is an autosomal dominant disease affecting the liver, heart and other organs with high variability. About 95% of ALGS cases are associated with pathogenic variants in JAG1, encoding the Jagged1 ligand that binds to Notch rece
Externí odkaz:
https://doaj.org/article/e6ae087feb1f4ef8823214d3d75727ed