Výsledky vyhledávání - "Vidita A, Vaidya"

Akademický článek

Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning

Autor: Megha Maheshwari, Aastha Singla, Anoop Rawat, Toshali Banerjee, Sthitapranjya Pati, Sneha Shah, Sudipta Maiti, Vidita A. Vaidya

Publikováno v: IBRO Neuroscience Reports, Vol 16, Iss , Pp 168-181 (2024)

Adult hippocampal neurogenesis is a lifelong process that involves the integration of newborn neurons into the hippocampal network, and plays a role in cognitive function and the modulation of mood-related behavior. Here, we sought to address the imp

Externí odkaz: https://doaj.org/article/62c4c82afdf248a99c302c3ab597a742

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Akademický článek

Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine beta-hydroxylase deficient mice

Autor: Darshana Kapri, Krishna C. Vadodaria, Karen S. Rommelfanger, Yvonne E. Ogbonmwan, L. Cameron Liles, Kimberly A. Fernandes-Thomas, Sonali S. Salvi, Basma F.A. Husain, David Weinshenker, Vidita A. Vaidya

Publikováno v: IBRO Neuroscience Reports, Vol 13, Iss , Pp 420-425 (2022)

Norepinephrine (NE), and specific adrenoceptors, have been reported to influence distinct aspects of adult hippocampal neurogenesis, including latent stem cell activation, progenitor proliferation, and differentiation. These findings are predominantl

Externí odkaz: https://doaj.org/article/384b53d4283246fbbb35144e26820ae1

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Akademický článek

Early Adversity and Accelerated Brain Aging: A Mini-Review

Autor: Pratik R. Chaudhari, Aastha Singla, Vidita A. Vaidya

Publikováno v: Frontiers in Molecular Neuroscience, Vol 15 (2022)

Early adversity is an important risk factor that influences brain aging. Diverse animal models of early adversity, including gestational stress and postnatal paradigms disrupting dam-pup interactions evoke not only persistent neuroendocrine dysfuncti

Externí odkaz: https://doaj.org/article/1b37a323ba6940d784caf8f144295aef

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Akademický článek

The Hallucinogenic Serotonin2A Receptor Agonist, 2,5-Dimethoxy-4-Iodoamphetamine, Promotes cAMP Response Element Binding Protein-Dependent Gene Expression of Specific Plasticity-Associated Genes in the Rodent Neocortex

Autor: Lynette A. Desouza, Madhurima Benekareddy, Sashaina E. Fanibunda, Farhan Mohammad, Balaganesh Janakiraman, Utkarsha Ghai, Tamar Gur, Julie A. Blendy, Vidita A. Vaidya

Publikováno v: Frontiers in Molecular Neuroscience, Vol 14 (2021)

Psychedelic compounds that target the 5-HT2A receptor are reported to evoke psychoplastogenic effects, including enhanced dendritic arborization and synaptogenesis. Transcriptional regulation of neuronal plasticity-associated genes is implicated in t

Externí odkaz: https://doaj.org/article/d8b628bfb60b400eb9db314691858edb

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Influence of Chronic Electroconvulsive Seizures on Plasticity-Associated Gene Expression and Perineuronal Nets Within the Hippocampi of Young Adult and Middle-Aged Sprague-Dawley Rats

Autor: Minal Jaggar, Shreya Ghosh, Balaganesh Janakiraman, Ashmita Chatterjee, Megha Maheshwari, Vani Dewan, Brendan Hare, Sukrita Deb, Dwight Figueiredo, Ronald S Duman, Vidita A Vaidya

Publikováno v: International Journal of Neuropsychopharmacology. 26:294-306

Background Electroconvulsive seizure therapy is often used in both treatment-resistant and geriatric depression. However, preclinical studies identifying targets of chronic electroconvulsive seizure (ECS) are predominantly focused on animal models in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09849802867bc6055a08a6bbe73cf536
https://doi.org/10.1093/ijnp/pyad008

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Akademický článek

Chronic postnatal chemogenetic activation of forebrain excitatory neurons evokes persistent changes in mood behavior

Autor: Sthitapranjya Pati, Kamal Saba, Sonali S Salvi, Praachi Tiwari, Pratik R Chaudhari, Vijaya Verma, Sourish Mukhopadhyay, Darshana Kapri, Shital Suryavanshi, James P Clement, Anant B Patel, Vidita A Vaidya

Publikováno v: eLife, Vol 9 (2020)

Early adversity is a risk factor for the development of adult psychopathology. Common across multiple rodent models of early adversity is increased signaling via forebrain Gq-coupled neurotransmitter receptors. We addressed whether enhanced Gq-mediat

Externí odkaz: https://doaj.org/article/008ee42d4e1743089cd4211a15bbec16

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Akademický článek

5-HT2A receptor deficiency alters the metabolic and transcriptional, but not the behavioral, consequences of chronic unpredictable stress

Autor: Minal Jaggar, Noelia Weisstaub, Jay A. Gingrich, Vidita A. Vaidya

Publikováno v: Neurobiology of Stress, Vol 7, Iss , Pp 89-102 (2017)

Chronic stress enhances risk for psychiatric disorders, and in animal models is known to evoke depression-like behavior accompanied by perturbed neurohormonal, metabolic, neuroarchitectural and transcriptional changes. Serotonergic neurotransmission,

Externí odkaz: https://doaj.org/article/1cd63b4eff644b36964d461a9f0ff5e6

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Akademický článek

Acute Chemogenetic Activation of CamKIIα-Positive Forebrain Excitatory Neurons Regulates Anxiety-Like Behaviour in Mice

Autor: Sonali S. Salvi, Sthitapranjya Pati, Pratik R. Chaudhari, Praachi Tiwari, Toshali Banerjee, Vidita A. Vaidya

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 13 (2019)

Anxiety disorders are amongst the most prevalent mental health disorders. Several lines of evidence have implicated cortical regions such as the medial prefrontal cortex, orbitofrontal cortex, and insular cortex along with the hippocampus in the top�

Externí odkaz: https://doaj.org/article/e2243ce4a3ac4fd7befab43a83f73107

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