Immortalised chronic myeloid leukemia (CML) derived mesenchymal stromal cells (MSCs) line retains the immunomodulatory and chemoprotective properties of CML patient-derived MSCs.

Autor: Benjamin ESB; Department of Haematology, Christian Medical College, Ranipet campus, India; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram, India., Vinod E; Department of Physiology, Christain Medical College, Vellore, India; Centre for Stem Cell Research (A Unit of inStem, Bengaluru), CMC Campus, Vellore, India., Illangeswaran RSS; Department of Haematology, Christian Medical College, Ranipet campus, India., Rajamani BM; Department of Haematology, Christian Medical College, Ranipet campus, India., Vidhyadharan RT; Department of Haematology, Christian Medical College, Ranipet campus, India., Bagchi A; Centre for Stem Cell Research (A Unit of inStem, Bengaluru), CMC Campus, Vellore, India., Maity A; Department of Haematology, Christian Medical College, Ranipet campus, India., Mohan A; Department of Haematology, Christian Medical College, Ranipet campus, India., Parasuraman G; Department of Physiology, Christain Medical College, Vellore, India., Amirtham SM; Department of Physiology, Christain Medical College, Vellore, India., Abraham A; Department of Haematology, Christian Medical College, Ranipet campus, India., Velayudhan SR; Department of Haematology, Christian Medical College, Ranipet campus, India; Centre for Stem Cell Research (A Unit of inStem, Bengaluru), CMC Campus, Vellore, India., Balasubramanian P; Department of Haematology, Christian Medical College, Ranipet campus, India. Electronic address: bpoonkuzhali@cmcvellore.ac.in.

Publikováno v: Cellular signalling [Cell Signal] 2024 Apr; Vol. 116, pp. 111067. Date of Electronic Publication: 2024 Jan 27.

Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo .

Autor: Rajamani BM; Department of Haematology, Christian Medical College, Vellore, India.; Department of Biotechnology, Thiruvalluvar University, Vellore, India., Illangeswaran RSS; Department of Haematology, Christian Medical College, Vellore, India.; Department of Biotechnology, Thiruvalluvar University, Vellore, India., Benjamin ESB; Department of Haematology, Christian Medical College, Vellore, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India., Balakrishnan B; Department of Haematology, Christian Medical College, Vellore, India.; Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore, India., Jebanesan DZP; Department of Haematology, Christian Medical College, Vellore, India.; Manipal Academy of Higher Education, Manipal, India., Das S; Department of Haematology, Christian Medical College, Vellore, India.; Department of Biotechnology, Thiruvalluvar University, Vellore, India., Pai AA; Department of Haematology, Christian Medical College, Vellore, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India., Vidhyadharan RT; Department of Haematology, Christian Medical College, Vellore, India., Mohan A; Department of Haematology, Christian Medical College, Vellore, India., Karathedath S; Department of Haematology, Christian Medical College, Vellore, India., Abraham A; Department of Haematology, Christian Medical College, Vellore, India., Mathews V; Department of Haematology, Christian Medical College, Vellore, India., Velayudhan SR; Department of Haematology, Christian Medical College, Vellore, India.; Centre for Stem Cell Research (CSCR), A Unit of InStem Bengaluru, Christian Medical College Campus, Vellore, India., Balasubramanian P; Department of Haematology, Christian Medical College, Vellore, India.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2023 May 31; Vol. 14, pp. 1187066. Date of Electronic Publication: 2023 May 31 (Print Publication: 2023).