Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vidhya Varghese"'
Publikováno v:
Current World Environment. 16:427-435
Environmental monitoring is a recent world-wide approach to save the future in line. The present study focuses on toxicity of heavy metals and pesticides on the freshwater aquarium fish (Poecilia reticulata and Poecilia sphenops). The study intense o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b28d5937e886fceba9fe766f65e421e
https://doi.org/10.12944/cwe.16.2.09
https://doi.org/10.12944/cwe.16.2.09
Publikováno v:
Cancer Research. 75:P1-08
Introduction TNBC is a heterogeneous disease and is often associated with expression of a stem cell signature (CD44+, CD24-). Recently platinum agents have been shown to improve the pathological response rates in the neo-adjuvant setting; however a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4f73091ff96ae83a7fa4504e065104c
https://doi.org/10.1158/1538-7445.sabcs14-p1-08-03
https://doi.org/10.1158/1538-7445.sabcs14-p1-08-03
Autor:
Naina Patel, Jennifer H. Steel, Vidhya Varghese, Susan Cleator, Adrian Lim, Laura M. Kenny, Kasia Kozlowski, Shairoz Merchant, Raoul Charles Coombes, Eric O. Aboagye, Sami Shousha
Publikováno v:
Cancer Research. 75:P5-01
Background: [18F]ICMT-11 is an isatin analogue which has been developed by our group as a novel PET radiotracer for studies of apoptosis in vivo. Preclinical studies have demonstrated subnanomolar affinity to caspase 3, and validated the potential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d8ae5f895297307ad6a4a2bca85cd9
https://doi.org/10.1158/1538-7445.sabcs14-p5-01-02
https://doi.org/10.1158/1538-7445.sabcs14-p5-01-02
Publikováno v:
Clinical Cancer Research. 21:A54-A54
Background: 5-Fluorouracil (5-FU) is one of the most commonly used chemotherapy drugs for the treatment of colorectal cancer in the adjuvant and metastatic disease settings. One of the main targets of 5-FU is the enzyme thymidylate synthase (TS). Hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::942990d4532eddea5fc320af26b1e0b4
https://doi.org/10.1158/1557-3265.pms14-a54
https://doi.org/10.1158/1557-3265.pms14-a54
Publikováno v:
Cancer Research. 74:LB-220
Background: Tumor resistance to chemotherapy is a major challenge in cancer therapeutics today. 5-Fluorouracil (5-FU) is one of the most commonly used cancer therapeutic agents. The Forkhead box transcription factor M1 (FOXM1) has been shown to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a614c2ecd15b97e36c595d9a9b110d4
https://doi.org/10.1158/1538-7445.am2014-lb-220
https://doi.org/10.1158/1538-7445.am2014-lb-220
Publikováno v:
Cancer Research. 73:P4-01
Background: Triple negative breast cancer (TNBC) has been associated with a high glycolytic rate. As a surrogate measure, the SUV of FDG uptake is found to be higher both in the TNBC and her2 positive phenotypes. Tumour lesion glycolysis (TLG) is a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64f9f2b2fc1ce71aefeb229ab11aea6
https://doi.org/10.1158/0008-5472.sabcs13-p4-01-22
https://doi.org/10.1158/0008-5472.sabcs13-p4-01-22
Publikováno v:
Cancer Research. 73:P3-01
Background; Glycolysis is one of the major metabolic pathways in cancer cells. The conversion of glucose to lactate in the presence of oxygen is a critical aerobic pathway that allows cancer cells to proliferate rapidly and the amount of lactate prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbef1d33cfc956a44008649d77dd1a7
https://doi.org/10.1158/0008-5472.sabcs13-p3-01-07
https://doi.org/10.1158/0008-5472.sabcs13-p3-01-07