Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Vidhya R Rao"'
Autor:
Inesa Lelyte, Vidhya R. Rao, Giedrius Kalesnykas, Symantas Ragauskas, Simon Kaja, Zubair Ahmed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Diabetic retinopathy (DR) is a multifactorial disease displaying vascular-associated pathologies, including vascular leakage and neovascularization, ultimately leading to visual impairment. However, animal models accurately reflecting these
Externí odkaz:
https://doaj.org/article/95bca3c8ce294d8c8cbb15c797015760
Autor:
Michael A Grassi, Vidhya R Rao, Siquan Chen, Dingcai Cao, Xiaoyu Gao, Patricia A Cleary, R Stephanie Huang, Andrew D Paterson, Rama Natarajan, Jalees Rehman, Timothy S Kern, DCCT/EDIC Research Group
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160504 (2016)
White blood cells have been shown in animal studies to play a central role in the pathogenesis of diabetic retinopathy. Lymphoblastoid cells are immortalized EBV-transformed primary B-cell leukocytes that have been extensively used as a model for con
Externí odkaz:
https://doaj.org/article/e7d108ef4b6e49109b225979ab3f8be2
Autor:
Evan B. Stubbs, Vidhya R. Rao
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The multifunctional profibrotic cytokine TGF-β2 is implicated in the pathophysiology of primary open angle glaucoma (POAG). While the underlying cause of POAG remains unclear, TGF-β2 dependent remodeling of the extracellular matrix (ECM) wi
Autor:
Sarah Burris, Miranda Burnette, Jeremiah J. Zartman, Eun-Kyoung Breuer, Saverio Gentile, Vidhya R. Rao, Simon Kaja, Daniela Fukushiro-Lopes, Debra Wyatt, Andrew T. Baker, Clodia Osipo, Dimitrios E. Kouzoukas, W. Keith Jones, Alexandra D. Hegel
Publikováno v:
Oncotarget
Potassium ion (K+) channels have been recently found to play a critical role in cancer biology. Despite that pharmacologic manipulation of ion channels is recognized as an important therapeutic approach, very little is known about the effects of targ
Autor:
Katherine Lansu, Basabi Rana, Mathew Perez-Neut, Lauren Haar, WK Jones, Saverio Gentile, Sreevidya Santha, Vidhya R. Rao
Publikováno v:
Oncotarget
Ion channels play a major factor in maintaining cellular homeostasis but very little is known about the role of these proteins in cancer biology. In this work we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a cri
Autor:
Vidhya R. Rao, Alexandra D. Zigrossi, Jamie C. Floss, Simon Kaja, Peter Koulen, Evan B. Stubbs, Victoria J. Wisniewski, Anita K. Ghosh
Publikováno v:
Antioxidants, Vol 9, Iss 324, p 324 (2020)
Antioxidants
Volume 9
Issue 4
Antioxidants
Volume 9
Issue 4
Optic nerve head astrocytes are the specialized glia cells that provide structural and trophic support to the optic nerve head. In response to cellular injury, optic nerve head astrocytes undergo reactive astrocytosis, the process of cellular activat
Autor:
Raji Rajesh Lenin, Vidhya R. Rao, Matthias Clauss, Uday B. Kompella, Shanta Alli, Peter G. Nagy, Rajashekhar Gangaraju
Publikováno v:
Journal of cellular biochemistry. 119(10)
Diabetic retinopathy (DR) is the leading cause of vision loss among working-age adults. The interplay between hyperglycemia and endothelial activation in inducing endoplasmic reticulum (ER) stress pathways and visual deficits in DR is not fully under
Publikováno v:
Cancers
Cancers, Vol 7, Iss 2, Pp 849-875 (2015)
Cancers, Vol 7, Iss 2, Pp 849-875 (2015)
Changes of the electrical charges across the surface cell membrane are absolutely necessary to maintain cellular homeostasis in physiological as well as in pathological conditions. The opening of ion channels alter the charge distribution across the
Publikováno v:
Oncotarget
// Mathew Perez-Neut 1 , Vidhya R. Rao 1 and Saverio Gentile 1 1 Department of Molecular Pharmacology and Therapeutics, Loyola University Chicago, Maywood, IL, USA Correspondence to: Saverio Gentile, email: // Keywords : p21 waf/cip , hERG1/Kv11.1, b
Publikováno v:
Investigative Opthalmology & Visual Science. 60:3613
Purpose POAG is a progressive optic neuropathy that is currently the leading cause of irreversible blindness worldwide. While the underlying cause of POAG remains unclear, TGF-β2-dependent remodeling of the extracellular matrix (ECM) within the trab