Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vidhi Gaur"'
Autor:
Vidhi Gaur, Timothy Connor, Andrew Sanigorski, Sheree D. Martin, Clinton R. Bruce, Darren C. Henstridge, Simon T. Bond, Kevin A. McEwen, Lyndal Kerr-Bayles, Trent D. Ashton, Cassandra Fleming, Min Wu, Lisa S. Pike Winer, Denise Chen, Gregg M. Hudson, John W.R. Schwabe, Keith Baar, Mark A. Febbraio, Paul Gregorevic, Frederick M. Pfeffer, Ken R. Walder, Mark Hargreaves, Sean L. McGee
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2802-2810 (2016)
Drugs that recapitulate aspects of the exercise adaptive response have the potential to provide better treatment for diseases associated with physical inactivity. We previously observed reduced skeletal muscle class IIa HDAC (histone deacetylase) tra
Externí odkaz:
https://doaj.org/article/edcebf20f6354f6bb76e658132df2dd0
Autor:
Mark A. Febbraio, Gregory R. Steinberg, Kylie Venardos, Kathryn Aston-Mourney, Roelof van Ewijk, Timothy Connor, Stefan M. Gehrig, Mark Hargreaves, Courtney Swinton, Ken Walder, Gordon S. Lynch, Darren C. Henstridge, Sean L. McGee, Shona Morrison, Sheree D. Martin, Vidhi Gaur
Publikováno v:
Diabetes, Obesity and Metabolism. 19:936-943
Aims/Hypothesis Current drugs used to treat metabolic diseases such as obesity and type 2 diabetes have limited efficacy in directly normalising muscle insulin action, while exercise is effective in enhancing this aspect of metabolic disease. We rece
Autor:
Mark A. Febbraio, Kevin A. McEwen, Sheree D. Martin, John W.R. Schwabe, Lisa S. Pike Winer, Darren C. Henstridge, Andrew Sanigorski, Clinton R. Bruce, Vidhi Gaur, Sean L. McGee, Simon T. Bond, Frederick M. Pfeffer, Cassandra L. Fleming, Min Wu, Paul Gregorevic, Trent D. Ashton, Mark Hargreaves, Denise Chen, Timothy Connor, Keith Baar, Ken Walder, Lyndal Kerr-Bayles, Gregg M. Hudson
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2802-2810 (2016)
SummaryDrugs that recapitulate aspects of the exercise adaptive response have the potential to provide better treatment for diseases associated with physical inactivity. We previously observed reduced skeletal muscle class IIa HDAC (histone deacetyla
Autor:
Vidhi, Gaur, Timothy, Connor, Kylie, Venardos, Darren C, Henstridge, Sheree D, Martin, Courtney, Swinton, Shona, Morrison, Kathryn, Aston-Mourney, Stefan M, Gehrig, Roelof, van Ewijk, Gordon S, Lynch, Mark A, Febbraio, Gregory R, Steinberg, Mark, Hargreaves, Ken R, Walder, Sean L, McGee
Publikováno v:
Diabetes, obesitymetabolism. 19(7)
To determine the effect of Scriptaid, a compound that can replicate aspects of the exercise adaptive response through disruption of the class IIa histone deacetylase (HDAC) corepressor complex, on muscle insulin action in obesity.Diet-induced obese m
Autor:
Suryaprakash Raichur, Song Hooi Teh, Vidhi Gaur, Sean L. McGee, Yun Chau Long, Mark Hargreaves, Kenji Ohwaki, Jun Kusunoki
Publikováno v:
Journal of Molecular Endocrinology. 49:203-211
The class IIa histone deacetylases (HDACs) act as transcriptional repressors by altering chromatin structure through histone deacetylation. This family of enzymes regulates muscle development and phenotype, through regulation of muscle-specific genes