Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vida Forstnerič"'
Autor:
Duško Lainšček, Vida Forstnerič, Veronika Mikolič, Špela Malenšek, Peter Pečan, Mojca Benčina, Matjaž Sever, Helena Podgornik, Roman Jerala
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The CRISPR/Cas system has emerged as a powerful and versatile genome engineering tool. Here the authors couple Cas9 to effector protein Exonuclease III via coiled-coil mediated interactions, termed CCExo, leading to increased deletion sizes and enhan
Externí odkaz:
https://doaj.org/article/f7179363155344cf811fce7648c9fef4
Autor:
Vida Forstnerič, Irena Oven, Jernej Ogorevc, Duško Lainšček, Arne Praznik, Tina Lebar, Roman Jerala, Simon Horvat
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Background Forkhead box P3+ (FOXP3 +) regulatory T cells (Tregs) are a subset of lymphocytes, critical for the maintenance of immune homeostasis. Loss-of-function mutations of the FOXP3 gene in animal models and humans results in loss of dif
Externí odkaz:
https://doaj.org/article/958b1bde5f514972bb719df8c2cda876
Autor:
Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno E. Correia, David Peterhoff, Ralf Wagner, Valter Bergant, Alexander Herrmann, Andreas Pichlmair, Roman Jerala
Publikováno v:
Vaccines, Vol 9, Iss 5, p 431 (2021)
The response of the adaptive immune system is augmented by multimeric presentation of a specific antigen, resembling viral particles. Several vaccines have been designed based on natural or designed protein scaffolds, which exhibited a potent adaptiv
Externí odkaz:
https://doaj.org/article/74784734a4764cf7add9be42d5336cc7
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006574 (2017)
Flagellin is a wide-spread bacterial virulence factor sensed by the membrane-bound Toll-like receptor 5 (TLR5) and by the intracellular NAIP5/NLRC4 inflammasome receptor. TLR5 recognizes a conserved region within the D1 domain of flagellin, crucial f
Externí odkaz:
https://doaj.org/article/f7c5e11db10d44f0829e2b568afd0dd7
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158894 (2016)
Toll-like receptor 5 (TLR5) is a receptor of the innate immune system that recognizes flagellin from certain bacterial species and triggers an inflammatory response. The Salmonella dublin flagellin in complex with zebrafish TLR5 has been crystallized
Externí odkaz:
https://doaj.org/article/d71ca5c57fcb450b8d0966a5aeb2d485
Correlation between Phenotype and Genotype in CTNNB1 Syndrome: A Systematic Review of the Literature
Autor:
Špela Miroševič, Shivang Khandelwal, Petra Sušjan, Nina Žakelj, David Gosar, Vida Forstnerič, Duško Lainšček, Roman Jerala, Damjan Osredkar
Publikováno v:
International Journal of Molecular Sciences. 23:12564
The CTNNB1 Syndrome is a rare neurodevelopmental disorder associated with developmental delay, intellectual disability, and delayed or absent speech. The aim of the present study is to systematically review the available data on the prevalence of cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6cd8fdfecd53c3a38694a0af9e118b
https://doi.org/10.3390/ijms232012564
https://doi.org/10.3390/ijms232012564
Autor:
Mateja Manček-Keber, Florence Pojer, Alexander Herrmann, Tina Fink, Vida Forstnerič, Gregor Anderluh, Duško Lainšček, Roman Jerala, David L. Hacker, Hana Esih, Peter Pečan, Lucija Kadunc, Tjaša Plaper, Žiga Strmšek, Neža Omersa, Špela Malenšek, Andreas Pichlmair, Petra Dekleva, Mojca Benčina, Bruno E. Correia, David Peterhoff, Kelvin Lau, Jana Aupič, Sara Vidmar, Valter Bergant, Sara Orehek, Iva Hafner-Bratkovič, Ralf Wagner
Publikováno v:
Vaccines, Vol 9, Iss 431, p 431 (2021)
Vaccines
Volume 9
Issue 5
Vaccines
Volume 9
Issue 5
The response of the adaptive immune system is augmented by multimeric presentation of a specific antigen, resembling viral particles. Several vaccines have been designed based on natural or designed protein scaffolds, which exhibited a potent adaptiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6133a91e93c20c845908c38f717426d2
https://www.mdpi.com/2076-393X/9/5/431
https://www.mdpi.com/2076-393X/9/5/431
Publikováno v:
E-Poster Presentations.
Background Chronic myeloid leukemia (CML) is a myeloproliferative neoplastic disease, occurring in 1 to 2 cases per 100.000 adults, which accounts this type of cancer for approximately 15% of newly diagnosed leukemia in adult patients. The diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27e6f7daf8aab69e34e5a2bf998e5790
https://doi.org/10.1136/jitc-2020-itoc7.106
https://doi.org/10.1136/jitc-2020-itoc7.106
Autor:
Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno Correia, David Peterhoff, Ralf Wagner, Roman Jerala
Effective and safe vaccines against SARS-CoV-2 are highly desirable to prevent casualties and societal cost caused by Covid-19 pandemic. The receptor binding domain (RBD) of the surface-exposed spike protein of SARS-CoV-2 represents a suitable target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::395156b4f1ac8c3a6c85c45f799a5162
https://doi.org/10.1101/2020.08.28.244269
https://doi.org/10.1101/2020.08.28.244269
Publikováno v:
FEBS lettersReferences. 594(15)
The considerable potential of engineered cells compels the development of strategies for the stringent control of gene expression. A promising approach is the introduction of a premature stop codon (PTC) into a selected gene that is expressed only in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e41e9581064d33f6af6e1727bf5d4d
https://pubmed.ncbi.nlm.nih.gov/32401336
https://pubmed.ncbi.nlm.nih.gov/32401336