Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Victorio Jauregui-Matos"'
1
Akademický článek
Nucleoside Analogs in ADAR Guide Strands Enable Editing at 5′-GA Sites
Autor: Aashrita Manjunath, Jeff Cheng, Kristen B Campbell, Casey S. Jacobsen, Herra G. Mendoza, Leila Bierbaum, Victorio Jauregui-Matos, Erin E. Doherty, Andrew J. Fisher, Peter A. Beal
Publikováno v: Biomolecules, Vol 14, Iss 10, p 1229 (2024)
Adenosine Deaminases Acting on RNA (ADARs) are members of a family of RNA editing enzymes that catalyze the conversion of adenosine into inosine in double-stranded RNA (dsRNA). ADARs’ selective activity on dsRNA presents the ability to correct muta
Externí odkaz: https://doaj.org/article/74f0470ef24d475282890dd62e8033e0
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3
ADAR activation by inducing a syn conformation at guanosine adjacent to an editing site
Autor: Erin E Doherty, Agya Karki, Xander E Wilcox, Herra G Mendoza, Aashrita Manjunath, Victorio Jauregui Matos, Andrew J Fisher, Peter A Beal
Publikováno v: Nucleic Acids Research. 50:10857-10868
ADARs (adenosine deaminases acting on RNA) can be directed to sites in the transcriptome by complementary guide strands allowing for the correction of disease-causing mutations at the RNA level. However, ADARs show bias against editing adenosines wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a4e78948fe451c3f349cd543423ea1
https://doi.org/10.1093/nar/gkac897
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4
Nucleoside analogs in ADAR guide strands targeting 5'-UA̲ sites
Autor: Hannah F. Brinkman, Victorio Jauregui Matos, Herra G. Mendoza, Erin E. Doherty, Peter A. Beal
Publikováno v: RSC chemical biology, vol 4, iss 1
Adenosine deaminases that act on RNA (ADARs) can be directed to predetermined sites in transcriptomes by forming duplex structures with exogenously delivered guide RNAs (gRNAs). They can then catalyze the hydrolytic deamination of adenosine to inosin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ea52a40a829c716db4890f6c286679
https://escholarship.org/uc/item/0kj944p5
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5
Synthesis of a novel brominated vinylic fatty acid with antileishmanial activity that effectively inhibits the Leishmania topoisomerase IB enzyme mediated by halogen bond formation
Autor: Victorio Jauregui Matos, Adriano D. Andricopulo, Néstor M. Carballeira, Rafael Balaña-Fouce, Leonardo L. G. Ferreira, Leilani M. Lotti Diaz, Denisse Alequín, Rosa M. Reguera, Yolanda Pérez-Pertejo, Mikhail Y. Golovko
Publikováno v: Pure and Applied Chemistry. 91:1405-1416
Many marine derived fatty acids, mainly from sponges, possess vinylic halogenated moieties (bromine or iodine) but their assessment as antileishmanial candidates remains elusive. In this work, we undertook the first total synthesis of a novel series
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6f5a55eeb146bec507bcbdd82d57883
https://doi.org/10.1515/pac-2018-1113
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7
Akademický článek
Nucleoside Analogs in ADAR Guide Strands Enable Editing at 5′-G A Sites.
Autor: Manjunath, Aashrita1 (AUTHOR) amanjunath@ucdavis.edu, Cheng, Jeff1 (AUTHOR) jefcheng@ucdavis.edu, Campbell, Kristen B1 (AUTHOR) kcampbell@ucdavis.edu, Jacobsen, Casey S.1 (AUTHOR) csjacobsen@ucdavis.edu, Mendoza, Herra G.1 (AUTHOR) hdgrajo@ucdavis.edu, Bierbaum, Leila1 (AUTHOR) labierbaum@ucdavis.edu, Jauregui-Matos, Victorio1 (AUTHOR) vijaureguim@ucdavis.edu, Doherty, Erin E.1 (AUTHOR) eedoherty@ucdavis.edu, Fisher, Andrew J.1,2 (AUTHOR) ajfisher@ucdavis.edu, Beal, Peter A.1 (AUTHOR) pabeal@ucdavis.edu
Publikováno v: Biomolecules (2218-273X). Oct2024, Vol. 14 Issue 10, p1229. 14p.
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