Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Victorine Muse"'
Autor:
Oliver Bracko, Lindsay K. Vinarcsik, Jean C. Cruz Hernández, Nancy E. Ruiz-Uribe, Mohammad Haft-Javaherian, Kaja Falkenhain, Egle M. Ramanauskaite, Muhammad Ali, Aditi Mohapatra, Madisen A. Swallow, Brendah N. Njiru, Victorine Muse, Pietro E. Michelucci, Nozomi Nishimura, Chris B. Schaffer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Obesity is linked to increased risk for and severity of Alzheimer’s disease (AD). Cerebral blood flow (CBF) reductions are an early feature of AD and are also linked to obesity. We recently showed that non-flowing capillaries, caused by ad
Externí odkaz:
https://doaj.org/article/e9f076f1a1ac4a1ca9d345e6325e1739
Autor:
Christina Vasalou, Douglas Ferguson, Weimin Li, Victorine Muse, Francis D. Gibbons, Silvia Sonzini, Guangnong Zhang, Petar Pop-Damkov, Eric Gangl, Srividya B. Balachander, Shenghua Wen, Alwin G. Schuller, Sanyogitta Puri, Mariarosa Mazza, Marianne Ashford, Adrian J. Fretland, Dermot F. McGinnity, Rhys D. O. Jones
Publikováno v:
Molecular Pharmaceutics. 19:172-187
A physiologically based pharmacokinetic model was developed to describe the tissue distribution kinetics of a dendritic nanoparticle and its conjugated active pharmaceutical ingredient (API) in plasma, liver, spleen, and tumors. Tumor growth data fro
Autor:
Jong Seok Ahn, Shadi Ebrahimian, Shaunagh McDermott, Sanghyup Lee, Laura Naccarato, John F. Di Capua, Markus Y. Wu, Eric W. Zhang, Victorine Muse, Benjamin Miller, Farid Sabzalipour, Bernardo C. Bizzo, Keith J. Dreyer, Parisa Kaviani, Subba R. Digumarthy, Mannudeep K. Kalra
Publikováno v:
JAMA network open. 5(8)
The efficient and accurate interpretation of radiologic images is paramount.To evaluate whether a deep learning-based artificial intelligence (AI) engine used concurrently can improve reader performance and efficiency in interpreting chest radiograph
Autor:
Fatemeh Homayounieh, Subba Digumarthy, Shadi Ebrahimian, Johannes Rueckel, Boj Friedrich Hoppe, Bastian Oliver Sabel, Sailesh Conjeti, Karsten Ridder, Markus Sistermanns, Lei Wang, Alexander Preuhs, Florin Ghesu, Awais Mansoor, Mateen Moghbel, Ariel Botwin, Ramandeep Singh, Samuel Cartmell, John Patti, Christian Huemmer, Andreas Fieselmann, Clemens Joerger, Negar Mirshahzadeh, Victorine Muse, Mannudeep Kalra
Publikováno v:
JAMA Network Open
Key Points Question Can artificial intelligence (AI) improve detection of pulmonary nodules on chest radiographs at different levels of detection difficulty? Findings In this diagnostic study, AI-aided interpretation was associated with significantly
Autor:
Nancy E. Ruiz-Uribe, Lindsay K. Vinarcsik, Nozomi Nishimura, Madisen Swallow, Brendah N. Njiru, Aditi Mohapatra, Kaja Falkenhain, Egle M. Ramanauskaite, Jean C. Cruz Hernandez, Pietro Michelucci, Victorine Muse, Oliver Bracko, Mohammad Haft-Javaherian, Chris B. Schaffer, Muhammad Ali
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Obesity is linked to increased risk for and severity of Alzheimer’s disease (AD). Cerebral blood flow (CBF) reductions are an early feature of AD and are also linked to obesity. We recently showed that non-flowing capillaries, caused by adhered neu
Autor:
Nozomi Nishimura, Linjing Fang, Mohammad Haft-Javaherian, Victorine Muse, Chris B. Schaffer, Mert R. Sabuncu
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213539 (2019)
PLoS ONE
PLoS ONE
The health and function of tissue rely on its vasculature network to provide reliable blood perfusion. Volumetric imaging approaches, such as multiphoton microscopy, are able to generate detailed 3D images of blood vessels that could contribute to ou
Autor:
Oliver Bracko, Joan Zhou, Madison Swallow, Yiming Kang, Jieyu Zheng, Mohammad Haft-Javaherian, Gabriel Otte, Calvin J. Kersbergen, Chris B. Schaffer, Brendah N. Njiru, Lindsay K. Vinarcsik, Nozomi Nishimura, Costantino Iadecola, Laibaik Park, Muhammad Ali, Iryna Ivasyk, Jean C. Cruz Hernandez, Victorine Muse, Elizabeth Slack, Jeffrey D. Beverly
Publikováno v:
Alzheimer's & Dementia. 14
Autor:
Vincent Doyeux, Joan Zhou, Gabriel Otte, Victorine Muse, Maxime Berg, Marta Cortes-Canteli, Elizabeth M. Davenport, Oliver Bracko, Myriam Peyrounette, Laibaik Park, Costantino Iadecola, Mohammad Haft-Javaherian, Nozomi Nishimura, Jean C. Cruz Hernandez, Calvin J. Kersbergen, Chris B. Schaffer, Lindsay K. Vinarcsik, Sylvie Lorthois, Yiming Kang, Charles P. Lin, Yohan Davit, Daniel A. Rivera, Jeffrey D. Beverly, Amy F. Smith, Sidney Strickland, Iryna Ivasyk
Publikováno v:
Nature neuroscience
Nature neuroscience, vol 22, iss 3
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2019, 22 (3), pp.413-420. ⟨10.1038/s41593-018-0329-4⟩
Nature neuroscience, vol 22, iss 3
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2019, 22 (3), pp.413-420. ⟨10.1038/s41593-018-0329-4⟩
International audience; Cerebral blood flow (CBF) reductions in Alzheimer’s disease patients and related mouse models have been recognized for decades, but the underlying mechanisms and resulting consequences for Alzheimer’s disease pathogenesis
Autor:
Marta Cortes-Canteli, Nozomi Nishimura, Vincent Doyeux, Calvin J. Kersbergen, Joan Zhou, Elizabeth M. Davenport, Iryna Ivasyk, Yohan Davit, Maxime Berg, Costantino Iadecola, Myriam Peyrounette, Gabriel Otte, Jean C. Cruz Hernandez, Laibaik Park, Amy F. Smith, Sidney Strickland, Victorine Muse, Jeffrey D. Beverly, Oliver Bracko, Mohammad Haft-Javaherian, Chris B. Schaffer, Yiming Kang, Lindsay K. Vinarcsik, Sylvie Lorthois
The existence of cerebral blood flow (CBF) reductions in Alzheimer’s disease (AD) patients and related mouse models has been known for decades, but the underlying mechanisms and the resulting impacts on cognitive function and AD pathogenesis remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e099ebc5933306a48ba7bf20ed773da1
https://doi.org/10.1101/226886
https://doi.org/10.1101/226886
Autor:
Costantino Iadecola, Jeffrey D. Beverly, Nozomi Nishimura, Joan Zhou, Oliver Bracko, Mohammad Haft-Javaherian, Calvin J. Kersbergen, Gabriel Otte, Thom P. Santisakultarm, Laibaik Park, Chris B. Schaffer, Jean C. Cruz Hernandez, Victorine Muse, Yiming Kang, Elizabeth Slack, Iryna Ivasyk, Lindsay K. Vinarcsik
Publikováno v:
Optics in the Life Sciences Congress.
Using in vivo nonlinear microscopy, we found 2% of brain capillaries were occluded by an adhered leukocyte in Alzheimer’s disease mice. Blocking this adhesion eliminated these stalls, improved brain blood flow by 30%, and restored spatial memory.