Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Victoria Zadorozhny"'
Autor:
Sneh Lata, Naser Ansari-Pour, Fadi Towfic, Nicholas Stong, Sitharthan Kamalakaran, Maria Ortiz, Sarah Gooding, Victoria Zadorozhny, Erin Flynt, Anjan Thakurta, Kao-Tai Tsai, Konstantinos Mavrommatis, Dan Rozelle
Publikováno v:
Blood. 134:365-365
Introduction Multiple myeloma (MM) is a heterogeneous disease defined by genetic lesions including translocations, chromosomal copy number aberrations (CNA), and mutations. Large-scale analyses of genomic data from newly-diagnosed patients (ndMM) hav
Autor:
Victoria Zadorozhny, Erin Flynt, Anjan Thakurta, Kao-Tai Tsai, Sarah Gooding, Dan Rozelle, Paola Neri, Nizar J. Bahlis, Naser Ansari-Pour, Maria Ortiz, Fadi Towfic, Paresh Vyas, Michael Amatangelo
Publikováno v:
Blood. 134:1793-1793
Myeloma survival has been significantly improved by novel therapies over the past two decades. Immunomodulatory agents (IMiDs, Lenalidomide (LEN) and Pomalidomide (POM)) are a backbone of current treatment strategies. But myeloma (MM) remains incurab
Autor:
Joanna Pawlak, Benjamin F. Cravatt, Kim Masuda, Stefan Freigang, Yang Liu, Victoria Zadorozhny, Lisa Kain, Rana Herro, Nicolas Schrantz, Philippe Krebs, Paul B. Savage, Luc Teyton, Michele K. McKinney, Albert Bendelac
Publikováno v:
Journal of Clinical Investigation
The Journal of clinical investigation
The Journal of clinical investigation
The potent regulatory properties of NKT cells render this subset of lipid-specific T cells a promising target for immunotherapeutic interventions. The marine sponge glycolipid alpha-galactosylceramide (alphaGalCer) is the proto-typic NKT cell agonist
Autor:
Richard S. Garfein, Valeru Crudu, Ashu Chawla, Grace Lin, Maria Tarcela Gler, Timothy C. Rodwell, Camilla Rodrigues, Victoria Zadorozhny, Donald G. Catanzaro, Antonino Catanzaro, Matt Hoshide, K. D. Eisenach, Lynn Jackson, Edward Desmond, Nazir Ahmed Ismail, Lishi Qian, Min Kim, James T. Douglas, Faramarz Valafar, Thomas C. Victor, Jessica N Torres
Publikováno v:
Journal of clinical microbiology, vol 52, iss 3
Rodwell, TC; Valafar, F; Douglas, J; Qian, L; Garfein, RS; Chawla, A; et al.(2014). Predicting extensively drug-resistant Mycobacterium tuberculosis phenotypes with genetic mutations. Journal of Clinical Microbiology, 52(3), 781-789. doi: 10.1128/JCM.02701-13. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7n40b2xz
Rodwell, TC; Valafar, F; Douglas, J; Qian, L; Garfein, RS; Chawla, A; et al.(2014). Predicting extensively drug-resistant Mycobacterium tuberculosis phenotypes with genetic mutations. Journal of Clinical Microbiology, 52(3), 781-789. doi: 10.1128/JCM.02701-13. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7n40b2xz
Molecular diagnostic methods based on the detection of mutations conferring drug resistance are promising technologies for rapidly detecting multidrug-/extensively drug-resistant tuberculosis (M/XDR TB), but large studies of mutations as markers of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efd42fb942c85e3634cf3148998e1c0
https://escholarship.org/uc/item/7n40b2xz
https://escholarship.org/uc/item/7n40b2xz
Autor:
Lisa Kain, Albert Bendelac, Yang Liu, Victoria Zadorozhny, Elise Landais, Wulf Palinski, Shenglou Deng, Luc Teyton, Stefan Freigang, Kenji Yoshida, Paul B. Savage
Publikováno v:
The Journal of clinical investigation, vol 122, iss 11
J Clin Invest
J Clin Invest
NKT cells are innate-like T cells with powerful regulatory functions that are a promising target for immunotherapy. The efficacy of glycolipids, such as the prototypic NKT cell antagonist α-galactosylceramide (αGalCer), is currently being evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998356142f03719c38f51fd6168510d1
https://escholarship.org/uc/item/0744z8kz
https://escholarship.org/uc/item/0744z8kz
Autor:
Feridoun, Karimi-Busheri, Victoria, Zadorozhny, Tony, Li, Helen, Lin, Daniel L, Shawler, Habib, Fakhrai
Publikováno v:
Journal of stem cells. 6(1)
Lung cancer is the number one killer among all cancers and is estimated to kill over 170,000 individual in 2010 in the United States. However, little is understood about the role of tumor initiating cells in the lung cancer and whether these cells pl
Publikováno v:
Cell and Tissue Banking
Cryopreservation is a common procedure widely used in biological and clinical sciences. Similar protocols are also applied in preserving cancer stem cells, a field with high promises and challenges. Specific cell surface membrane proteins are conside
Publikováno v:
Cryobiology. 60(3)
Cancer stem cells are believed to be the driving force behind tumor progression and development. Despite extensive studies on the effects of cryopreservation on embryonic and hematopoietic stem cells there is only limited data that directly deals wit
Autor:
Antonino Catanzaro, Thomas C. Victor, Elizabeth M. Streicher, Victoria Zadorozhny, Afif Elghraoui, Camilla Rodrigues, Amy P Goodmanson, Frederick A. Sirgel, Ashu Chawla, Jessica N Torres, Anu Amallraja, Faramarz Valafar, Timothy C. Rodwell, Sarah M Ramirez-Busby, Valeru Crudu, Maria Tarcela Gler, Lynthia V. Paul, Donald G. Catanzaro
Publikováno v:
Emerging Microbes & Infections
We report the discovery and confirmation of 23 novel mutations with previously undocumented role in isoniazid (INH) drug resistance, in catalase-peroxidase (katG) gene of Mycobacterium tuberculosis (Mtb) isolates. With these mutations, a synonymous m
Publikováno v:
Cancer Research. 71:LB-107
Lung cancer is the highest cancer killer and the rate of death in this disease is approximately equal to death caused by colon, breast, prostate, and pancreas combined. However, little is understood about the role of tumor initiating cells in the lun