Výsledky vyhledávání - "Victoria Y. Shilova"

Akademický článek

Silencing of PKG1 Gene Mimics Effect of Aging and Sensitizes Rat Vascular Smooth Muscle Cells to Cardiotonic Steroids: Impact on Fibrosis and Salt Sensitivity

Autor: Olga V. Fedorova, Victoria Y. Shilova, Valentina Zernetkina, Ondrej Juhasz, Wen Wei, Edward G. Lakatta, Alexei Y. Bagrov

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)

Background Marinobufagenin, NKA (Na/K‐ATPase) inhibitor, causes vasoconstriction and induces fibrosis via inhibition of Fli1 (Friend leukemia integration‐1), a negative regulator of collagen synthesis. In vascular smooth muscle cells (VSMC), ANP

Externí odkaz: https://doaj.org/article/9810b244ddd64249a4cef89ddbfcc9e2

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Akademický článek

Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro‐Fibrotic Signaling

Autor: Steven T. Haller, Yanling Yan, Christopher A. Drummond, Joe Xie, Jiang Tian, David J. Kennedy, Victoria Y. Shilova, Zijian Xie, Jiang Liu, Christopher J. Cooper, Deepak Malhotra, Joseph I. Shapiro, Olga V. Fedorova, Alexei Y. Bagrov

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 10 (2016)

BackgroundExperimental uremic cardiomyopathy causes cardiac fibrosis and is causally related to the increased circulating levels of the cardiotonic steroid, marinobufagenin (MBG), which signals through Na/K‐ATPase. Rapamycin is an inhibitor of the

Externí odkaz: https://doaj.org/article/9ab7f2b8d1104389af36bfc972a96b23

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Deletions of the cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE) genes, involved in the control of hydrogen sulfide biosynthesis, significantly affect lifespan and fitness components of Drosophila melanogaster

Autor: Mikhail V. Shaposhnikov, Alexey S. Zakluta, Nadezhda V. Zemskaya, Zulfiya G. Guvatova, Victoria Y. Shilova, Daria V. Yakovleva, Anastasia A. Gorbunova, Liubov A. Koval, Natalia S. Ulyasheva, Mikhail B. Evgen’ev, Olga G. Zatsepina, Alexey A. Moskalev

Publikováno v: Mechanisms of ageing and development. 203

The gasotransmitter hydrogen sulfide (H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38ed0ee03691fb47f08a4b812ba033a
https://pubmed.ncbi.nlm.nih.gov/35247392

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