Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Victoria Trembovler"'
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Traumatic brain injury (TBI), caused by mechanical impact to the brain, is a leading cause of death and disability among young adults, with slow and often incomplete recovery. Preemptive treatment strategies may increase the injury resilience of high
Externí odkaz:
https://doaj.org/article/08e44047feac4d3ba5ed70c5f1214a73
Autor:
David Panikashvili, Na'ama A. Shein, Raphael Mechoulam, Victoria Trembovler, Ron Kohen, Alexander Alexandrovich, Esther Shohami
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 2, Pp 257-264 (2006)
Endocannabinoids are involved in neuroprotection through numerous biochemical pathways. We have shown that the endocannabinoid 2-arachidonoyl glycerol (2-AG) is released in mouse brain after closed head injury (CHI), and treatment with exogenous 2-AG
Externí odkaz:
https://doaj.org/article/8ff596dcb3a24d998b21525851dcf445
Autor:
Gali Umschweif, Alexander G Alexandrovich, Victoria Trembovler, Michal Horowitz, Esther Shohami
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76129 (2013)
Preconditioning via heat acclimation (34°C 30 d) results in neuroprotection from traumatic brain injury due to constitutive as well as dynamic changes triggered by the trauma. Among these changes is Akt phosphorylation, which decreases apoptosis and
Externí odkaz:
https://doaj.org/article/17d18baf72ca4ef19e722ce7083215b9
Autor:
Esther Shohami, Alexander G. Alexandrovich, Uriel Elchalal, Philip Lazarovici, Victoria Trembovler, Galit Gincberg
Publikováno v:
Cytotherapy. 20:245-261
Background aims Human umbilical cord blood (HUCB) is an important source of stem cells for therapy of hematopoietic disorders and is a potential therapy for various neurological disorders, including traumatic brain injury (TBI). The expression of ner
Autor:
Esther Shohami, Victoria Trembovler, Alexander G. Alexandrovich, Aviva Breuer, Raphael Mechoulam, Reem Smoum, Aniv Mann
Publikováno v:
Journal of Neuroimmune Pharmacology. 10:356-363
The endocannabinoid (eCB) system helps recovery following traumatic brain injury (TBI). Treatment with 2-arachidonoylglycerol (2-AG), a cerebral eCB ligand, was found to ameliorate the secondary damage. Interestingly, the fatty acid amino acid amide
Autor:
Galit, Gincberg, Esther, Shohami, Victoria, Trembovler, Alexander G, Alexandrovich, Philip, Lazarovici, Uriel, Elchalal
Publikováno v:
Cytotherapy. 20(2)
Human umbilical cord blood (HUCB) is an important source of stem cells for therapy of hematopoietic disorders and is a potential therapy for various neurological disorders, including traumatic brain injury (TBI). The expression of nerve growth factor
Autor:
Arnon Nagler, Esther Shohami, Galit Gincberg, Hanan Galski, Ilan Matok, Alexander G. Alexandrovich, Peter I. Lelkes, Hadar Arien-Zakay, Sigal Liraz-Zaltsman, Uriel Elchalal, Victoria Trembovler, Gadi Cohen, Philip Lazarovici
Publikováno v:
Journal of Neurotrauma. 31:1405-1416
Treatment of traumatic brain injury (TBI) is still an unmet need. Cell therapy by human umbilical cord blood (HUCB) has shown promising results in animal models of TBI and is under evaluation in clinical trials. HUCB contains different cell populatio
Autor:
Esther Shohami, Larry I. Benowitz, Shlomit Dachir, Victoria Trembovler, Alexander G. Alexandrovich, Dalia Shabashov
Publikováno v:
Brain Research. 1555:78-88
Despite years of research, no effective therapy is yet available for the treatment of traumatic brain injury (TBI). The most prevalent and debilitating features in survivors of TBI are cognitive deficits and motor dysfunction. A potential therapeutic
Autor:
Raphael Mechoulam, Esther Shohami, Dafna Willner, Victoria Trembovler, Ayelet Cohen-Yeshurun, Alexander G. Alexandrovich, Ronen R. Leker
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:1242-1250
N-arachidonoyl-L-serine (AraS) is a novel neuroprotective endocannabinoid. We aimed to test the effects of exogenous AraS on neurogenesis after traumatic brain injury (TBI). The effects of AraS on neural progenitor cells (NPC) proliferation, survival
Autor:
Maximilian Peters, Moshe Parnas, Alexander Alexandrovich, Esther Shohami, Baruch Minke, Lutz Birnbaumer, Victoria Trembovler
Publikováno v:
Journal of Neurotrauma. 29:2831-2834
Death of Central Nervous System (CNS) neurons following traumatic brain injury (TBI) is a complex process arising from a combination of factors, many of which are still unknown. It has been found that inhibition of transient receptor potential (TRP)