Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Victoria Rydengård"'
Autor:
Anneli M L Edström Hägerwall, Victoria Rydengård, Per Fernlund, Matthias Mörgelin, Maria Baumgarten, Alexander M Cole, Martin Malmsten, Birthe B Kragelund, Ole E Sørensen
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002625 (2012)
The innate immune factors controlling Candida albicans are mostly unknown. Vulvovaginal candidiasis is common in women and affects approximately 70-75% of all women at least once. Despite the propensity of Candida to colonize the vagina, transmission
Externí odkaz:
https://doaj.org/article/b7db41646a98403aa7a3a23465010907
Autor:
Martina Kalle, Praveen Papareddy, Gopinath Kasetty, Matthias Mörgelin, Mariena J A van der Plas, Victoria Rydengård, Martin Malmsten, Barbara Albiger, Artur Schmidtchen
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51313 (2012)
Gram-negative sepsis is accompanied by a disproportionate innate immune response and excessive coagulation mainly induced by endotoxins released from bacteria. Due to rising antibiotic resistance and current lack of other effective treatments there i
Externí odkaz:
https://doaj.org/article/4d33efee0d2b4918b0441361aca2c79d
Autor:
Praveen Papareddy, Victoria Rydengård, Mukesh Pasupuleti, Björn Walse, Matthias Mörgelin, Anna Chalupka, Martin Malmsten, Artur Schmidtchen
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000857 (2010)
The coagulation system is characterized by the sequential and highly localized activation of a series of serine proteases, culminating in the conversion of fibrinogen into fibrin, and formation of a fibrin clot. Here we show that C-terminal peptides
Externí odkaz:
https://doaj.org/article/f247dbe4ef904433a25e43745f0cf568
Autor:
Mukesh Pasupuleti, Markus Roupe, Victoria Rydengård, Krystyna Surewicz, Witold K Surewicz, Anna Chalupka, Martin Malmsten, Ole E Sörensen, Artur Schmidtchen
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7358 (2009)
BACKGROUND: Cellular prion-related protein (PrP(c)) is a cell-surface protein that is ubiquitously expressed in the human body. The multifunctionality of PrP(c), and presence of an exposed cationic and heparin-binding N-terminus, a feature characteri
Externí odkaz:
https://doaj.org/article/44560bb5d1834eb3bc3a972666ac7e59
Autor:
Victoria Rydengård, Oonagh Shannon, Katarina Lundqvist, Lukasz Kacprzyk, Anna Chalupka, Anna-Karin Olsson, Matthias Mörgelin, Willi Jahnen-Dechent, Martin Malmsten, Artur Schmidtchen
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000116 (2008)
Fungi, such as Candida spp., are commonly found on the skin and at mucosal surfaces. Yet, they rarely cause invasive infections in immunocompetent individuals, an observation reflecting the ability of our innate immune system to control potentially i
Externí odkaz:
https://doaj.org/article/fe0c149059424733bb4a4e39e53c6fdc
Autor:
Martin Malmsten, Artur Schmidtchen, Praveen Papareddy, Matthias Mörgelin, Victoria Rydengård, Bo Svensson, Gopinath Kasetty, Björn Walse, Martina Kalle
Publikováno v:
Journal of Innate Immunity. 3:471-482
Serine proteases of the S1 family have maintained a common structure over an evolutionary span of more than one billion years, and evolved a variety of substrate specificities and diverse biological roles, involving digestion and degradation, blood c
Autor:
Martin Malmsten, Victoria Rydengård, Praveen Papareddy, Matthias Mörgelin, Katarina Lundqvist, Martina Kalle, Artur Schmidtchen, Gopinath Kasetty, Barbara Albiger
Publikováno v:
Journal of Biological Chemistry. 285:28387-28398
Tissue factor pathway inhibitor (TFPI) inhibits tissue factor-induced coagulation, but may, via its C terminus, also modulate cell surface, heparin, and lipopolysaccharide interactions as well as participate in growth inhibition. Here we show that C-
Publikováno v:
FEBS Journal. 274:377-389
Histidine-rich glycoprotein (HRGP), an abundant heparin-binding protein found in plasma and thrombocytes, exerts antibacterial effects against Gram-positive bacteria (Enterococcus faecalis and Staphylococcus aureus) and Gram-negative bacteria (Escher
Publikováno v:
FEBS Journal. 273:2399-2406
Antimicrobial peptides are effector molecules of the innate immune system. We have recently shown that peptides containing multiples of the heparin-binding Cardin and Weintraub motifs AKKARA and ARKKAAKA exert antimicrobial activities. Here, we show
Autor:
Emma Andersson, Matthias Mörgelin, Lars Björck, Victoria Rydengård, Artur Schmidtchen, Andreas Sonesson
Publikováno v:
European Journal of Biochemistry. 271:1219-1226
Antimicrobial peptides are effector molecules of the innate immune system. We recently showed that the human antimicrobial peptides alpha-defensin and LL-37 bind to glycosaminoglycans (heparin and dermatan sulphate). Here we demonstrate the obverse,