Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Victoria Ridger"'
Autor:
Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance ath
Externí odkaz:
https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b
Autor:
Marwa M. Mahmoud, Jovana Serbanovic-Canic, Shuang Feng, Celine Souilhol, Rouyu Xing, Sarah Hsiao, Akiko Mammoto, Jing Chen, Markus Ariaans, Sheila E. Francis, Kim Van der Heiden, Victoria Ridger, Paul C. Evans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Blood flow influences atherosclerosis by generating wall shear stress, which alters endothelial cell (EC) physiology. Low shear stress induces dedifferentiation of EC through a process termed endothelial-to-mesenchymal transition (EndMT). Th
Externí odkaz:
https://doaj.org/article/d73073520d3c4c1ea3aaec80eeedf382
Autor:
Amanda Burnett, Ingrid Gomez, David Davila De Leon, Mark Ariaans, Pavlos Progias, Richard A. Kammerer, Guillermo Velasco, Marie Marron, Paul Hellewell, Victoria Ridger
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Angiopoietins are a family of growth factors that are ligands for the tyrosine kinase receptor, Tie2. Angiopoietin 1 (Ang-1) is agonistic for Tie2, plays a key role in blood vessel maturation and stability and has been shown to possess anti-
Externí odkaz:
https://doaj.org/article/13276e96cb424136925e3edbd894f7ad
Autor:
Marwa M. Mahmoud, Jovana Serbanovic-Canic, Shuang Feng, Celine Souilhol, Rouyu Xing, Sarah Hsiao, Akiko Mammoto, Jing Chen, Markus Ariaans, Sheila E. Francis, Kim Van der Heiden, Victoria Ridger, Paul C. Evans
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/f7db960ad367409a945ce2cf81ffa49f
Autor:
Victoria Ridger, Reece Dow
Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432dff575dffa636482ef2458c5305cf
https://eprints.whiterose.ac.uk/181108/7/Revised_Dow_and_Ridger_for_upload_to_WR.pdf
https://eprints.whiterose.ac.uk/181108/7/Revised_Dow_and_Ridger_for_upload_to_WR.pdf
Autor:
Helen Philippou, Helen R. McPherson, Khalid M. Naseem, Nathan L Asquith, Robert A. S. Ariëns, Lih T. Cheah, Stephen R. Baker, Simon D. Connell, Cédric Duval, Victoria Ridger, Marco M. Domingues, Matthew S. Hindle, Ramzi A. Ajjan
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Fibrinogen is essential for blood coagulation. The C-terminus of the fibrinogen α-chain (αC-region) is composed of an αC-domain and αC-connector. Two recombinant fibrinogen variants (α390 and α220) were produced to investigate the role of subre
Autor:
Ramzi A. Ajjan, Matthew S. Hindle, Victoria Ridger, Lih T. Cheah, Marco M. Domingues, Helen Philippou, Helen R. McPherson, Simon D. Connell, Khalid M. Naseem, Stephen R. Baker, Cédric Duval, Nathan L Asquith, Robert A. S. Ariëns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf3d87bd021d03dc3bb6f1db5cf7cab
https://doi.org/10.7554/elife.68761.sa2
https://doi.org/10.7554/elife.68761.sa2
Autor:
Nadira Yuldasheva, Victoria Ridger, Adomas Baranauskas, Simon D. Connell, Majid Ali, Richard M Cubbon, Stephen R. Baker, Ramzi A. Ajjan, Zaher Raslan, Helen Philippou, Cédric Duval, Helen R. McPherson, Khalid M. Naseem, Marc A. Bailey, Tímea Feller, Lih T. Cheah, Robert A. S. Ariëns
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Pulmonary embolism and stroke are thromboembolic diseases affecting >1 million people annually worldwide. Thromboembolism involves clot fragments affecting vital downstream organs such as the lung or brain. The mechanisms underpinning th
Autor:
Matthew S. Hindle, Cédric Duval, Victoria Ridger, Marco M. Domingues, Ramzi A. Ajjan, Simon D. Connell, Nathan L Asquith, Lih T. Cheah, Robert A. S. Ariëns, Helen Philippou, Helen R. McPherson, Khalid M. Naseem, Stephen R. Baker
Fibrinogen is essential for blood coagulation. The C-terminus of the fibrinogen α-chain (αC-region) is composed of an αC-domain and αC-connector. Two recombinant fibrinogen variants (α390 and α220) were produced to investigate the role of subre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::940b7a057e023ad978856d222b2bd23d
https://doi.org/10.1101/2021.05.07.443174
https://doi.org/10.1101/2021.05.07.443174
Autor:
Paul C. Evans, Hannah Roddie, Timothy J. A. Chico, Victoria Ridger, Celine Souilhol, Maria Fragiadaki, Jovana Serbanovic-Canic
Publikováno v:
Nature Reviews Cardiology. 17:52-63
Flowing blood generates a frictional force called shear stress that has major effects on vascular function. Branches and bends of arteries are exposed to complex blood flow patterns that exert low or low oscillatory shear stress, a mechanical environ