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Community Participation Trajectories over the 5 Years after Traumatic Brain Injury in Older Veterans: A U.S. Veterans Affairs Model Systems Study

Autor: Stefan Vasic, Bridget Xia, Mia E. Dini, Daniel W. Klyce, Carmen M. Tyler, Shannon B. Juengst, Victoria Liou-Johnson, Kelli G. Talley, Kristen Dams-O’Connor, Raj G. Kumar, Umesh M. Venkatesan, Brittany Engelman, Paul B. Perrin

Publikováno v: Trauma Care, Vol 4, Iss 2, Pp 174-188 (2024)

Background: Given the aging of the overall U.S. population, the resulting changes in healthcare needs especially among veterans, and the high prevalence of traumatic brain injury (TBI) among older adults, additional research is needed on community pa

Externí odkaz: https://doaj.org/article/2699f353e508492caace3c94fcf1f45c

Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis

Autor: Eamonn Kennedy, Spencer W. Liebel, Hannah M. Lindsey, Shashank Vadlamani, Pui-Wa Lei, Maheen M. Adamson, Martin Alda, Silvia Alonso-Lana, Tim J. Anderson, Celso Arango, Robert F. Asarnow, Mihai Avram, Rosa Ayesa-Arriola, Talin Babikian, Nerisa Banaj, Laura J. Bird, Stefan Borgwardt, Amy Brodtmann, Katharina Brosch, Karen Caeyenberghs, Vince D. Calhoun, Nancy D. Chiaravalloti, David X. Cifu, Benedicto Crespo-Facorro, John C. Dalrymple-Alford, Kristen Dams-O’Connor, Udo Dannlowski, David Darby, Nicholas Davenport, John DeLuca, Covadonga M. Diaz-Caneja, Seth G. Disner, Ekaterina Dobryakova, Stefan Ehrlich, Carrie Esopenko, Fabio Ferrarelli, Lea E. Frank, Carol E. Franz, Paola Fuentes-Claramonte, Helen Genova, Christopher C. Giza, Janik Goltermann, Dominik Grotegerd, Marius Gruber, Alfonso Gutierrez-Zotes, Minji Ha, Jan Haavik, Charles Hinkin, Kristen R. Hoskinson, Daniela Hubl, Andrei Irimia, Andreas Jansen, Michael Kaess, Xiaojian Kang, Kimbra Kenney, Barbora Keřková, Mohamed Salah Khlif, Minah Kim, Jochen Kindler, Tilo Kircher, Karolina Knížková, Knut K. Kolskår, Denise Krch, William S. Kremen, Taylor Kuhn, Veena Kumari, Junsoo Kwon, Roberto Langella, Sarah Laskowitz, Jungha Lee, Jean Lengenfelder, Victoria Liou-Johnson, Sara M. Lippa, Marianne Løvstad, Astri J. Lundervold, Cassandra Marotta, Craig A. Marquardt, Paulo Mattos, Ahmad Mayeli, Carrie R. McDonald, Susanne Meinert, Tracy R. Melzer, Jessica Merchán-Naranjo, Chantal Michel, Rajendra A. Morey, Benson Mwangi, Daniel J. Myall, Igor Nenadić, Mary R. Newsome, Abraham Nunes, Terence O’Brien, Viola Oertel, John Ollinger, Alexander Olsen, Victor Ortiz García de la Foz, Mustafa Ozmen, Heath Pardoe, Marise Parent, Fabrizio Piras, Federica Piras, Edith Pomarol-Clotet, Jonathan Repple, Geneviève Richard, Jonathan Rodriguez, Mabel Rodriguez, Kelly Rootes-Murdy, Jared Rowland, Nicholas P. Ryan, Raymond Salvador, Anne-Marthe Sanders, Andre Schmidt, Jair C. Soares, Gianfranco Spalleta, Filip Španiel, Scott R. Sponheim, Alena Stasenko, Frederike Stein, Benjamin Straube, April Thames, Florian Thomas-Odenthal, Sophia I. Thomopoulos, Erin B. Tone, Ivan Torres, Maya Troyanskaya, Jessica A. Turner, Kristine M. Ulrichsen, Guillermo Umpierrez, Daniela Vecchio, Elisabet Vilella, Lucy Vivash, William C. Walker, Emilio Werden, Lars T. Westlye, Krista Wild, Adrian Wroblewski, Mon-Ju Wu, Glenn R. Wylie, Lakshmi N. Yatham, Giovana B. Zunta-Soares, Paul M. Thompson, Mary Jo Pugh, David F. Tate, Frank G. Hillary, Elisabeth A. Wilde, Emily L. Dennis

Publikováno v: Brain Sciences, Vol 14, Iss 7, p 669 (2024)

Deficits in memory performance have been linked to a wide range of neurological and neuropsychiatric conditions. While many studies have assessed the memory impacts of individual conditions, this study considers a broader perspective by evaluating ho

Externí odkaz: https://doaj.org/article/1cd9cc3673eb4e819bd68e603b342672

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Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors

Autor: Pamela A. Lochhead, Julie A. Tucker, Natalie J. Tatum, Jinhua Wang, David Oxley, Andrew M. Kidger, Victoria P. Johnson, Megan A. Cassidy, Nathanael S. Gray, Martin E. M. Noble, Simon J. Cook

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Selective ERK5 inhibitors target ERK5 kinase activity, but they do not phenocopy the effects of ERK5 genetic depletion. Here, the authors demonstrate that the direct interaction of these inhibitors to ERK5 kinase domain induces conformational changes

Externí odkaz: https://doaj.org/article/74f91df61c624308a4815d6adcffb1f9