Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Victoria N Safronova"'
Autor:
Pavel V. Panteleev, Eugene B. Pichkur, Roman N. Kruglikov, Alena Paleskava, Olga V. Shulenina, Ilia A. Bolosov, Ivan V. Bogdanov, Victoria N. Safronova, Sergey V. Balandin, Valeriya I. Marina, Tatiana I. Kombarova, Olga V. Korobova, Olga V. Shamova, Alexander G. Myasnikov, Alexander I. Borzilov, Ilya A. Osterman, Petr V. Sergiev, Alexey A. Bogdanov, Olga A. Dontsova, Andrey L. Konevega, Tatiana V. Ovchinnikova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The antimicrobial resistance crisis along with challenges of antimicrobial discovery revealed the vital necessity to develop new antibiotics. Many of the animal proline-rich antimicrobial peptides (PrAMPs) inhibit the process of bacterial tr
Externí odkaz:
https://doaj.org/article/9de33db467d84874bde0aeaf8143a9ce
Autor:
Pavel V. Panteleev, Julia S. Teplovodskaya, Anastasia D. Utkina, Anastasia A. Smolina, Roman N. Kruglikov, Victoria N. Safronova, Ilia A. Bolosov, Olga V. Korobova, Alexander I. Borzilov, Tatiana V. Ovchinnikova
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1453 (2024)
Background: Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient molecular factors of innate immunity that play a key role in host defense. The study of the diversity of animal defense peptides has important applications in the context
Externí odkaz:
https://doaj.org/article/c6f91744bf774d36bd145df3519b6b2f
Autor:
Pavel A. Mironov, Alexander S. Paramonov, Olesya V. Reznikova, Victoria N. Safronova, Pavel V. Panteleev, Ilia A. Bolosov, Tatiana V. Ovchinnikova, Zakhar O. Shenkarev
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 332 (2024)
Capitellacin is the β-hairpin membrane-active cationic antimicrobial peptide from the marine polychaeta Capitella teleta. Capitellacin exhibits antibacterial activity, including against drug-resistant strains. To gain insight into the mechanism of c
Externí odkaz:
https://doaj.org/article/4f11ec4017154912a397387fa578ed5e
Autor:
Pavel V. Panteleev, Victoria N. Safronova, Shuting Duan, Alexey S. Komlev, Ilia A. Bolosov, Roman N. Kruglikov, Tatiana I. Kombarova, Olga V. Korobova, Eugenia S. Pereskokova, Alexander I. Borzilov, Igor A. Dyachenko, Olga V. Shamova, Yu Huang, Qiong Shi, Tatiana V. Ovchinnikova
Publikováno v:
Marine Drugs, Vol 21, Iss 12, p 639 (2023)
Marine polychaetes represent an extremely rich and underexplored source of novel families of antimicrobial peptides (AMPs). The rapid development of next generation sequencing technologies and modern bioinformatics approaches allows us to apply them
Externí odkaz:
https://doaj.org/article/0d4a4a8fe7e14fa5b140590dbd98ea0d
Autor:
Ilia A. Bolosov, Pavel V. Panteleev, Sergei V. Sychev, Veronika A. Khokhlova, Victoria N. Safronova, Ilia Yu. Toropygin, Tatiana I. Kombarova, Olga V. Korobova, Eugenia S. Pereskokova, Alexander I. Borzilov, Tatiana V. Ovchinnikova, Sergey V. Balandin
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2047 (2023)
Protegrin-1 (PG-1) is a cationic β-hairpin pore-forming antimicrobial peptide having a membranolytic mechanism of action. It possesses in vitro a potent antimicrobial activity against a panel of clinically relevant MDR ESKAPE pathogens. However, its
Externí odkaz:
https://doaj.org/article/8c3916aeba9c45db91f460464b014802
Autor:
Pavel V. Panteleev, Victoria N. Safronova, Roman N. Kruglikov, Ilia A. Bolosov, Tatiana V. Ovchinnikova
Publikováno v:
Membranes, Vol 13, Iss 4, p 438 (2023)
Proline-rich antimicrobial peptides (PrAMPs) having a potent antimicrobial activity and a modest toxicity toward mammalian cells attract much attention as new templates for the development of antibiotic drugs. However, a comprehensive understanding o
Externí odkaz:
https://doaj.org/article/407aaae789514b5786cd0a950ce56a5b
Autor:
Victoria N. Safronova, Ilia A. Bolosov, Roman N. Kruglikov, Olga V. Korobova, Eugenia S. Pereskokova, Alexander I. Borzilov, Pavel V. Panteleev, Tatiana V. Ovchinnikova
Publikováno v:
Marine Drugs, Vol 20, Iss 8, p 517 (2022)
In recent years, new antibiotics targeting multidrug resistant Gram-negative bacteria have become urgently needed. Therefore, antimicrobial peptides are considered to be a novel perspective class of antibacterial agents. In this study, a panel of nov
Externí odkaz:
https://doaj.org/article/d35fbc35f29c42299f4b9d5d1baa3d3e
Autor:
Pavel V. Panteleev, Victoria N. Safronova, Roman N. Kruglikov, Ilia A. Bolosov, Ivan V. Bogdanov, Tatiana V. Ovchinnikova
Publikováno v:
Membranes, Vol 12, Iss 5, p 515 (2022)
Over recent years, a growing number of bacterial species have become resistant to clinically relevant antibiotics. Proline-rich antimicrobial peptides (PrAMPs) having a potent antimicrobial activity and a negligible toxicity toward mammalian cells at
Externí odkaz:
https://doaj.org/article/36107f2d85fc462db9924a258868b3ef
Autor:
Victoria N. Safronova, Pavel V. Panteleev, Stanislav V. Sukhanov, Ilia Y. Toropygin, Ilia A. Bolosov, Tatiana V. Ovchinnikova
Publikováno v:
Marine Drugs, Vol 20, Iss 3, p 167 (2022)
Among the most potent and proteolytically resistant antimicrobial peptides (AMPs) of animal origin are molecules forming a β-hairpin structure stabilized by disulfide bonds. In this study, we investigated the mechanism of action and therapeutic pote
Externí odkaz:
https://doaj.org/article/51aac7c4917a417aa46f17907c3b6b07
Autor:
Pavel V. Panteleev, Andrey V. Tsarev, Victoria N. Safronova, Olesia V. Reznikova, Ilia A. Bolosov, Sergei V. Sychev, Zakhar O. Shenkarev, Tatiana V. Ovchinnikova
Publikováno v:
Marine Drugs, Vol 18, Iss 12, p 620 (2020)
Endogenous antimicrobial peptides (AMPs) are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. Among the most active and stable under physiological conditions AMPs are the peptides of animal origin that a
Externí odkaz:
https://doaj.org/article/8592032287b3485084ef433f346a12b4