Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Victoria Marini"'
Autor:
Victoria Marini, Fedor Nikulenkov, Pounami Samadder, Sissel Juul, Birgitta R. Knudsen, Lumir Krejci
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background DNA-protein cross-links (DPCs) are one of the most deleterious DNA lesions, originating from various sources, including enzymatic activity. For instance, topoisomerases, which play a fundamental role in DNA metabolic processes suc
Externí odkaz:
https://doaj.org/article/f27960dd49134ebbb90288484d64163e
Publikováno v:
Ecology and Society, Vol 26, Iss 4, p 44 (2021)
In recent decades, the landscape in northeastern Entre Ríos Province, Argentina has undergone significant changes because of the expansion of eucalyptus plantations. These plantations have generated perceived socioeconomic and environmental impacts
Externí odkaz:
https://doaj.org/article/1751ee32f3a843cdb47ab0533a1215a6
Autor:
Steven J. Brill, Lumir Krejci, Melita Chavdarova, Victoria Marini, Michael Lisby, Alexandra Sisakova, Dana Vigasova, Hana Sedlackova
Publikováno v:
Nucleic Acids Research
Chavdarova, M, Marini, V, Sisakova, A, Sedlackova, H, Vigasova, D, Brill, S J, Lisby, M & Krejci, L 2015, ' Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates ', Nucleic Acids Research, vol. 43, no. 7, pp. 3626-3642 . https://doi.org/10.1093/nar/gkv198
Chavdarova, M, Marini, V, Sisakova, A, Sedlackova, H, Vigasova, D, Brill, S J, Lisby, M & Krejci, L 2015, ' Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates ', Nucleic Acids Research, vol. 43, no. 7, pp. 3626-3642 . https://doi.org/10.1093/nar/gkv198
A variety of DNA lesions, secondary DNA structures or topological stress within the DNA template may lead to stalling of the replication fork. Recovery of such forks is essential for the maintenance of genomic stability. The structure-specific endonu
Autor:
Ľubomír Tomáška, Vladimír Pevala, Eva Kutejová, Jozef Nosek, Dominika Truban, Július Košťan, Lumir Krejci, Nina Kunová, Victoria Marini, Marlene Brandstetter, Jana Bellová, Jacob A. Bauer
Publikováno v:
Nucleic acids research 44(5), 2227-2239 (2016). doi:10.1093/nar/gkv1529
Nucleic Acids Research
Nucleic Acids Research
To study the mechanisms involved in the maintenance of a linear mitochondrial genome we investigated the biochemical properties of the recombination protein Mgm101 from Candida parapsilosis. We show that CpMgm101 complements defects associated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d944629e79cf2ed973b46ccb00145a9c
https://phaidra.univie.ac.at/o:930749
https://phaidra.univie.ac.at/o:930749
Autor:
Lumir Krejci, Smaranda Willcox, Jack D. Griffith, Jozef Nosek, Jana Bakkaiova, Victoria Marini, Lubomir Tomaska
Publikováno v:
Bioscience Reports
Comparative biochemical analysis of mtHMG proteins from distantly related yeast species revealed that they exhibit a preference for recombination/replication intermediates. We discuss how these biochemical characteristics relate to the role of mtHMG
Publikováno v:
Biophysical Journal. 95(9):4361-4371
Clinically ineffective transplatin [trans-diamminedichloridoplatinum(II)] is used in the studies of the structure-pharmacological activity relationship of platinum compounds. In addition, a number of transplatin analogs exhibit promising toxic effect
Autor:
Jana Kasparkova, Viktor Brabec, Nicholas Farrell, Olga Novakova, Victoria Marini, Petros Christofis
Publikováno v:
Nucleic Acids Research
Replacement of one ammine in clinically ineffective trans-[PtCl2(NH3)2] (transplatin) by a planar N-heterocycle, thiazole, results in significantly enhanced cytotoxicity. Unlike ‘classical’ cisplatin {cis-[PtCl2(NH3)2]} or transplatin, modificati
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 10:722-731
trans-Diaminedicholoroplatinum(II) complexes with one planar and one non-planar heterocyclic amine ligand were designed as new potential antitumor drugs. The X-ray crystallographic structures of trans-[PtCl2(4-picoline)(piperidine)] and trans-[PtCl2(
Autor:
Victoria Marini, Jana Kasparkova, Ana M. Pizarro, Olga Novakova, Viktor Brabec, Carmen Navarro-Ranninger, Radim Prokop
Publikováno v:
Biochemical Pharmacology. 67:1097-1109
The global modification of mammalian and plasmid DNAs by novel platinum compounds, trans -[PtCl 2 (NH 3 )(Am)], where Am=2-methylbutylamine or sec- butylamine was investigated in cell-free media using various biochemical and biophysical methods. Thes
Autor:
Olga Novakova, Yousef Najajreh, Victoria Marini, Jana Kasparkova, Dan Gibson, J.M. Pérez, Viktor Brabec
Publikováno v:
Journal of Biological Chemistry. 278:47516-47525
A paradigm for the structure-pharmacological activity relationship of bifunctional platinum antitumor drugs is that the trans isomer of antitumor cisplatin (transplatin) is clinically ineffective. To this end, however, several new complexes of the tr