Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Victoria Majam"'
Autor:
Miranda S Oakley, Joanna K Chorazeczewski, Maya Aleshnick, Vivek Anantharaman, Victoria Majam, Bhavna Chawla, Timothy G Myers, Qin Su, Winter A Okoth, Kazuyo Takeda, Adovi Akue, Mark KuKuruga, L Aravind, Sanjai Kumar
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201043 (2018)
Macrophages express a wide array of invariant receptors that facilitate host defense and mediate pathogenesis during pathogen invasion. We report on a novel population of CD11bhighCD14+F4/80+ macrophages that express TCRβ. This population expands dr
Externí odkaz:
https://doaj.org/article/d11403876389432dbbf5a9e4209c03f2
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24398 (2011)
BACKGROUND: Whole malaria parasites are highly effective in inducing immunity against malaria. Due to the limited success of subunit based vaccines in clinical studies, there has been a renewed interest in whole parasite-based malaria vaccines. Apart
Externí odkaz:
https://doaj.org/article/80c3f9992bc347bea8bffcd8e2c768e5
Autor:
Miranda S Oakley, Victoria Majam, Babita Mahajan, Noel Gerald, Vivek Anantharaman, Jerrold M Ward, Lawrence J Faucette, Thomas F McCutchan, Hong Zheng, Masaki Terabe, Jay A Berzofsky, L Aravind, Sanjai Kumar
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6793 (2009)
An in-depth knowledge of the host molecules and biological pathways that contribute towards the pathogenesis of cerebral malaria would help guide the development of novel prognostics and therapeutics. Genome-wide transcriptional profiling of the brai
Externí odkaz:
https://doaj.org/article/2f4846b49ab440dbad1384481861b27b
Autor:
Gabrielle Walsh, Wenshuo Zhou, Alexei Medvedev, Barbara K. Felber, Sanjai Kumar, Jasper Perry-Anderson, Victoria Majam, Konstantin Virnik, Ira Berkower
Publikováno v:
Biochem Biophys Res Commun
There is an urgent need for a malaria vaccine that can prevent severe disease in young children and adults. Despite earlier work showing an immunological mechanism for preventing infection and reducing disease severity, there is currently no reliable
Autor:
Demerise Johnston, Jill R Kelly, Michel Ledizet, Nathalie Lavoie, Robert P Smith, Jeffrey Parsonnet, Jonathan Schwab, John Stratidis, Scott Espich, Giyoung Lee, Kaitlin R Maciejewski, Yanhong Deng, Victoria Majam, Hong Zheng, Sougr-nooma Bonkoungou, June Stevens, Sanjai Kumar, Peter J Krause
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
Background Borrelia miyamotoi is a relapsing fever spirochete that relatively recently has been reported to infect humans. It causes an acute undifferentiated febrile illness that can include meningoencephalitis and relapsing fever. Like Borrelia bur
Autor:
Isabella A. Quakyi, Edward Essuman, Victoria Majam, Kazutoyo Miura, Ankit Puri, Kazuyo Takeda, Richard A. Skelton, Nitin Verma, Miranda S. Oakley, Godfree Mlambo, Abhai K. Tripathi, Hong Zheng, Merribeth J. Morin, Carole A. Long, Emily Locke, Scott Meredith, Sanjai Kumar
Publikováno v:
Science Translational Medicine. 13
Malaria vaccines that disrupt the Plasmodium life cycle in mosquitoes and reduce parasite transmission in endemic areas are termed transmission-blocking vaccines (TBVs). Despite decades of research, there are only a few Plasmodium falciparum antigens
Autor:
Irving L. Weissman, Winter A Okoth, Laughing Bear Torrez Dulgeroff, Sanjai Kumar, Michal Caspi Tal, Pallavi Malla, Victoria Majam, Maia Shoham, Joy Q He, Ying Ying Yiu, Miranda S. Oakley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Novel therapies are urgently needed that can ameliorate the clinical syndromes of cerebral malaria, the most severe consequences of Plasmodium infection, and thereby reduce malaria fatality. Monoclonal antibodies that target CD47, a “d
Autor:
Martha Sedegah, Richard L. Shimp, Miranda S. Oakley, Victoria Majam, Arnel Belmonte, Bhavna Chawla, David C. Kaslow, Babita Mahajan, Sanjai Kumar
The development of effective malaria vaccines is hampered by incomplete understanding of the immunological correlates of protective immunity. Recently, the moderate clinical efficacy of the Plasmodium falciparum circumsporozoite protein (CSP)-based R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed838bd34e158368b145ec58064403bc
https://europepmc.org/articles/PMC6759290/
https://europepmc.org/articles/PMC6759290/
Autor:
Sanjai Kumar, Tanjir Islam, Sharareh Eskandari, Michael R. Batzloff, Istvan Toth, Mei Fong Ho, Victoria Majam, Danielle I. Stanisic, Ali Zaid, Hanan A Al-Nazal, Waleed M. Hussein, Mariusz Skwarczynski, Michael F. Good, Emily Cooper, Ashwini Kumar Giddam
Publikováno v:
Cell Host & Microbe. 29:894-903.e5
Babesia spp. are tick-transmitted intra-erythrocytic protozoan parasites that infect humans and animals, causing a flu-like illness and hemolytic anemia. There is currently no human vaccine available. People most at risk of severe disease are the eld
Autor:
Victoria Majam, Sunali Patel, Sanjai Kumar, Phillip C. Williamson, Elena Grigorenko, Robert Duncan, Valerie Winkelman, Maria Rios, Caren Chancey, Carolyn Fisher, Germán Añez
Publikováno v:
The Journal of Molecular Diagnostics. 19:549-560
Molecular diagnostics are increasingly used in the blood bank industry. A device that can combine simultaneous detection of multiple targets with the flexibility of inclusion of emerging pathogens is desirable for testing blood products. A highly mul