Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Victoria M. Bedell"'
Autor:
Andrew R McKinstry-Wu, Andrzej Z Wasilczuk, Benjamin A Harrison, Victoria M Bedell, Mathangi J Sridharan, Jayce J Breig, Michael Pack, Max B Kelz, Alexander Proekt
Publikováno v:
eLife, Vol 8 (2019)
Traditionally, drug dosing is based on a concentration-response relationship estimated in a population. Yet, in specific individuals, decisions based on the population-level effects frequently result in over or under-dosing. Here, we interrogate the
Externí odkaz:
https://doaj.org/article/4213c79618d14c70a26b18d0e1174344
Autor:
Victoria M. Bedell, Alexander Meves, Stella P. Hartono, Priyabrata Mukherjee, Krishnendu Pal, Debabrata Mukhopadhyay, Luke H. Hoeppner, Rachel A. Kudgus, MaKayla R Serres, Stephen C. Ekker, Sk Kayum Alam, Madelyn O’Gorman, Stephanie R. Hall, Davis M. Seelig
Publikováno v:
Mayo Clin Proc
The negative health consequences of acute ultraviolet (UV) exposure are evident, with reports of 30,000 emergency room visits annually to treat the effects of sunburn in the United States alone. The acute effects of sunburn include erythema, edema, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac6fba4118e59da8f6401c19884167d
https://doi.org/10.1016/j.mayocp.2021.08.018
https://doi.org/10.1016/j.mayocp.2021.08.018
Autor:
Roderic G. Eckenhoff, Natarajan V. Bhanu, William P. Dailey, E. Railey White, David M Leace, Victoria M Bedell, Benjamin A. Garcia
Publikováno v:
ACS Chem Neurosci
The mechanisms of general anesthetics have been debated in the literature for many years and continue to be of great interest. As anesthetic molecules are notoriously difficult to study due to their low binding affinities and multitude of binding par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98931592a52e68dc8fb6d8b9c64eef61
https://pubmed.ncbi.nlm.nih.gov/33355437
https://pubmed.ncbi.nlm.nih.gov/33355437
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
The field of neuropharmacology has not yet achieved a full understanding of how the brain transitions between states of consciousness and drug-induced unconsciousness, or anesthesia. Many small molecules are used to alter human consciousness, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536322e26336a6b96d4ec07aa2dcd413
https://doi.org/10.1038/s41598-020-72669-1
https://doi.org/10.1038/s41598-020-72669-1
Publikováno v:
International Anesthesiology Clinics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ad646e0269f1e0ca133d668ae0a71ee
https://doi.org/10.1097/aia.0000000000000291
https://doi.org/10.1097/aia.0000000000000291
Autor:
Max B. Kelz, Jayce J Breig, Mathangi Sridharan, Victoria M Bedell, Andrew R. McKinstry-Wu, Andrzej Z. Wasilczuk, Michael Pack, Alex Proekt, Benjamin A Harrison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0097f29b67523cb7430d5be3f781c5a2
https://doi.org/10.7554/elife.50143.sa2
https://doi.org/10.7554/elife.50143.sa2
Autor:
Debabrata Mukhopadhyay, Ying Wang, Victoria M. Bedell, Sandip Suresh, Shamit K. Dutta, Changzoon Chun, Resham Bhattacharya, Xun Gong, Stephen C. Ekker, Ramani Ramchandran, Luke H. Hoeppner, Sutapa Sinha
Publikováno v:
Journal of Cell Science. 131
Vasculogenesis and angiogenesis are controlled by vascular endothelial growth factor A (VEGF-A). Dysregulation of these physiological processes contributes to the pathologies of heart disease, cancer and stroke. Rho GTPase proteins play an integral r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e89e6bcc831bcada5f12fcd1b6a430
https://doi.org/10.1242/jcs.217604
https://doi.org/10.1242/jcs.217604
Autor:
Daniel Marcato, Victoria M Bedell, Ravindra Peravali, Julia E. Dallman, Uwe Strähle, Maxwell Wray, Elena Buglo, Stephan Züchner, Ralf Mikut, Johannes Stegmaier, Will Scudder, Christian Pylatiuk
General anesthetics are small molecules that interact with and effect the function of many different proteins to promote loss of consciousness, amnesia, and sometimes, analgesia. Owing to the complexity of this state transition and the transient natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7733adc5c75b0ace181c70ed0b8b8954
https://doi.org/10.1016/bs.mie.2018.02.004
https://doi.org/10.1016/bs.mie.2018.02.004
Autor:
Alvin C.H. Ma, Scott C. Fahrenkrug, Stephen C. Ekker, Sumedha G. Penheiter, Daniel F. Carlson, Anskar Y.H. Leung, Randall G. Krug, Jarryd M. Campbell, Karl J. Clark, Jeffrey J. Essner, Victoria M. Bedell, Daniel F. Voytas, Ying Wang, Tanya L. Poshusta, Wenfang Tan, Colby G. Starker
Publikováno v:
Nature. 491:114-118
The zebrafish (Danio rerio) is increasingly being used to study basic vertebrate biology and human disease with a rich array of in vivo genetic and molecular tools. However, the inability to readily modify the genome in a targeted fashion has been a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8692b8ea4cb8d18552236aba176375ca
https://doi.org/10.1038/nature11537
https://doi.org/10.1038/nature11537
Autor:
Theodore A. Craig, Melissa S. McNulty, Victoria M. Bedell, Stephen C. Ekker, Tammy M. Greenwood, Rajiv Kumar
Publikováno v:
Gene Expression Patterns. 12:228-235
Sclerostin is a highly conserved, secreted, cystine-knot protein which regulates osteoblast function. Humans with mutations in the sclerostin gene (SOST), manifest increased axial and appendicular skeletal bone density with attendant complications. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c704e3e665987a3d0b266e6467733dd
https://doi.org/10.1016/j.gep.2012.04.003
https://doi.org/10.1016/j.gep.2012.04.003