Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Victoria M Perreau"'
Autor:
Helena Bujalka, Matthias Koenning, Stacey Jackson, Victoria M Perreau, Bernard Pope, Curtis M Hay, Stanlislaw Mitew, Andrew F Hill, Q Richard Lu, Michael Wegner, Rajini Srinivasan, John Svaren, Melanie Willingham, Ben A Barres, Ben Emery
Publikováno v:
PLoS Biology, Vol 11, Iss 8, p e1001625 (2013)
The myelination of axons is a crucial step during vertebrate central nervous system (CNS) development, allowing for rapid and energy efficient saltatory conduction of nerve impulses. Accordingly, the differentiation of oligodendrocytes, the myelinati
Externí odkaz:
https://doaj.org/article/946c16919be64298bd55ab4d3e4a051d
Identity-by-descent mapping to detect rare variants conferring susceptibility to multiple sclerosis.
Autor:
Rui Lin, Jac Charlesworth, Jim Stankovich, Victoria M Perreau, Matthew A Brown, ANZgene Consortium, Bruce V Taylor
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e56379 (2013)
Genome-wide association studies (GWAS) have identified around 60 common variants associated with multiple sclerosis (MS), but these loci only explain a fraction of the heritability of MS. Some missing heritability may be caused by rare variants that
Externí odkaz:
https://doaj.org/article/d25e2232bc334290992608243f48933a
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37635 (2012)
Mice lacking the axon guidance molecule EphA4 have been shown to exhibit extensive axonal regeneration and functional recovery following spinal cord injury. To assess mechanisms by which EphA4 may modify the response to neural injury a microarray was
Externí odkaz:
https://doaj.org/article/dfc398adefeb4cd6998e39076327241a
Autor:
Craig W. Lindsley, Victoria M. Perreau, Darren Riddy, Christopher J. Langmead, Andrew J Lawrence, Nicola A Chen, Katherine Huckstep, Jia Xiaojian, Leigh C Walker, Alice E. Berizzi, Jirawoot Srisontiyakul, Piyarat Govitrapong, Carrie K. Jones, Patricia Rueda, Arthur Christopoulos
Publikováno v:
Biological Psychiatry. 88:898-909
Background Alcohol use disorder (AUD) is a major socioeconomic burden on society, and current pharmacotherapeutic treatment options are inadequate. Aberrant alcohol use and seeking alters frontostriatal function. Methods We performed genome-wide RNA
Autor:
Leigh C, Walker, Alice E, Berizzi, Nicola A, Chen, Patricia, Rueda, Victoria M, Perreau, Katherine, Huckstep, Jirawoot, Srisontiyakul, Piyarat, Govitrapong, Jia, Xiaojian, Craig W, Lindsley, Carrie K, Jones, Darren M, Riddy, Arthur, Christopoulos, Christopher J, Langmead, Andrew J, Lawrence
Publikováno v:
Biological psychiatry. 88(12)
Alcohol use disorder (AUD) is a major socioeconomic burden on society, and current pharmacotherapeutic treatment options are inadequate. Aberrant alcohol use and seeking alters frontostriatal function.We performed genome-wide RNA sequencing and subse
Autor:
Shanshan Li, Thibault Renoir, Anthony J. Hannan, Wendy K. Adams, Michelle S. Zajac, Maarten van den Buuse, Victoria M. Perreau
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Huntington’s disease (HD) is a neurodegenerative disorder caused by a tandem repeat mutation encoding an expanded polyglutamine tract in the huntingtin protein, which leads to cognitive, psychiatric and motor dysfunction. Exposure to environmental
Autor:
Krista A. Dent, David Finkelstein, Victoria M. Perreau, Ashley I. Bush, Paul A. Adlard, He Xu
Publikováno v:
Journal of Alzheimer's Disease. 51:471-487
Background: There is strong evidence that iron homeostasis is impaired in the aging and Alzheimer’s disease (AD) brain and that this contributes to neurodegeneration. Apolipoprotein E (APOE) has been identified as the strongest genetic risk factor
Autor:
Juliet M. Taylor, Rhys D. Brady, Philip M Beart, Wah Chin Boon, Sandy R. Shultz, David P Q Clark, Enie Lei, Shilpi Dixit, Victoria M. Perreau
Publikováno v:
Neurochemical research. 44(6)
Traumatic brain injury triggers neuroinflammation that may contribute to progressive neurodegeneration. We investigated patterns of recruitment of astrocytes and microglia to inflammation after brain trauma by firstly characterising expression profil
There is growing evidence that exercise benefits recovery of neuromuscular function from spinal cord injury (SCI). However, the effect of exercise on gene expression in the spinal cord is poorly understood. We used oligonucleotide microarrays to comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b5a100e7f0979793e20266fc0ddf4b
https://europepmc.org/articles/PMC6009109/
https://europepmc.org/articles/PMC6009109/
Autor:
Anna Jonas, William Doherty, Victoria M. Perreau, Rainer Akkermann, Michele D. Binder, Trevor J. Kilpatrick, Helmut Butzkueven, Melissa Gresle, David Wynick, Fiona E. Holmes, Andrew L. Gundlach, Vilija Jokubaitis, Mark Marriott, Pik Ying Soo, Holly S. Cate, Stefan Thiem, Junhua Xiao
Publikováno v:
Glia. 63:1005-1020
In order to further investigate the molecular mechanisms that regulate oligodendrocyte (OC) survival, we utilized microarrays to characterize changes in OC gene expression after exposure to the cytokines neurotrophin3, insulin, or leukemia inhibitory