Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Victoria L. Seewaldt"'
Autor:
Nan Jiang, Andras Saftics, Eugenia Romano, Ima Ghaeli, Cristal Resto, Vanessa Robles, Saumya Das, Kendall Van Keuren-Jensen, Victoria L. Seewaldt, Tijana Jovanovic-Talisman
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Patients with HER2-positive breast cancer can significantly benefit from HER2-directed therapy – such as the monoclonal antibody trastuzumab. However, some patients can develop therapy resistance or change HER2 status. Thus, we
Externí odkaz:
https://doaj.org/article/dfd432c8e2da4fa18fab1236c2c53ce7
Autor:
Christina M. Vidal, Jackelyn A. Alva-Ornelas, Nancy Zhuo Chen, Parijat Senapati, Jerneja Tomsic, Vanessa Myriam Robles, Cristal Resto, Nancy Sanchez, Angelica Sanchez, Terry Hyslop, Nour Emwas, Dana Aljaber, Nick Bachelder, Ernest Martinez, David Ann, Veronica Jones, Robert A. Winn, Lucio Miele, Augusto C. Ochoa, Eric C. Dietze, Rama Natarajan, Dustin Schones, Victoria L. Seewaldt
Publikováno v:
Cancers, Vol 16, Iss 15, p 2735 (2024)
Background: Epigenetic changes link medical, social, and environmental factors with cardiovascular and kidney disease and, more recently, with cancer. The mechanistic link between metabolic health and epigenetic changes is only starting to be investi
Externí odkaz:
https://doaj.org/article/02b2eea48af0405c91e13275156d282a
Autor:
Pei-Ying Wu, Michelle Van Scoyk, Stephanie S. McHale, Chu-Fang Chou, Gregory Riddick, Kamran Farouq, Bin Hu, Vita Kraskauskiene, Jennifer Koblinski, Charles Lyons, Arjun Rijal, Vignesh Vudatha, Dongyu Zhang, Jose G. Trevino, Rachit D. Shah, Patrick Nana-Sinkam, Yong Huang, Shwu-Fan Ma, Imre Noth, Chanita Hughes-Halbert, Victoria L. Seewaldt, Ching-Yi Chen, Robert A. Winn
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108858- (2024)
Summary: Lung cancer is the third most common cancer with Black/AA men showing higher risk and poorer outcomes than NHW men. Lung cancer disparities are multifactorial, driven by tobacco exposure, inequities in care access, upstream health determinan
Externí odkaz:
https://doaj.org/article/2b1b617e9e464c16a2b0c6f8fca1416f
Autor:
Kavitha Mukund, Jackelyn A. Alva-Ornelas, Adam L. Maddox, Divya Murali, Darya Veraksa, Andras Saftics, Jerneja Tomsic, David Frankhouser, Meagan Razo, Tijana Jovanovic-Talisman, Victoria L. Seewaldt, Shankar Subramaniam
Publikováno v:
Cancers, Vol 16, Iss 3, p 553 (2024)
Trastuzumab therapy in HER2+ breast cancer patients has mixed success owing to acquired resistance to therapy. A detailed understanding of downstream molecular cascades resulting from trastuzumab resistance is yet to emerge. In this study, we investi
Externí odkaz:
https://doaj.org/article/ec46e4f922164f8da81ba8718909b339
Autor:
Christopher Sistrunk, Nora Tolbert, Maria Dulfary Sanchez-Pino, Loretta Erhunmwunsee, Nikita Wright, Veronica Jones, Terry Hyslop, Gustavo Miranda-Carboni, Eric C. Dietze, Ernest Martinez, Sophia George, Augusto C. Ochoa, Robert A. Winn, Victoria L. Seewaldt
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Racist and discriminatory federal, state, and local housing policies significantly contribute to disparities in cardiovascular disease incidence and mortality for individuals that self-identify as Black or African American. Here we highlight three ke
Externí odkaz:
https://doaj.org/article/558e0d34c0634c9aa0a48b7ef615e078
Autor:
Nikita Jinna, Tijana Jovanovic-Talisman, Mark LaBarge, Rama Natarajan, Rick Kittles, Christopher Sistrunk, Padmashree Rida, Victoria L. Seewaldt
Publikováno v:
Cancers, Vol 14, Iss 18, p 4484 (2022)
Black/African-American (AA) women, relative to their White/European-American (EA) counterparts, experience disproportionately high breast cancer mortality. Central to this survival disparity, Black/AA women have an unequal burden of aggressive breast
Externí odkaz:
https://doaj.org/article/8c5bcfc00fd648cd8387b83533657017
Autor:
Parijat Senapati, Hiroyuki Kato, Michael Lee, Amy Leung, Christine Thai, Angelica Sanchez, Emily J. Gallagher, Derek LeRoith, Victoria L. Seewaldt, David K. Ann, Dustin E. Schones
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background Hyperinsulinemia, the presence of excess insulin relative to glucose in the blood, is considered to be a poor prognostic indicator for patients with triple-negative breast cancer (TNBC). mTOR, a downstream effector of insulin, enh
Externí odkaz:
https://doaj.org/article/d7335b0fd4b044189496f088802659ef
Autor:
Adam L. Maddox, Matthew S. Brehove, Kiarash R. Eliato, Andras Saftics, Eugenia Romano, Michael F. Press, Joanne Mortimer, Veronica Jones, Daniel Schmolze, Victoria L. Seewaldt, Tijana Jovanovic-Talisman
Publikováno v:
Cancers, Vol 14, Iss 11, p 2795 (2022)
Trastuzumab, the prototype HER2-directed therapy, has markedly improved survival for women with HER2-positive breast cancers. However, only 40–60% of women with HER2-positive breast cancers achieve a complete pathological response to chemotherapy c
Externí odkaz:
https://doaj.org/article/1dec9f9042a145b796cf5d89c208d746
Autor:
Veronica C. Jones, Eric C. Dietze, Tijana Jovanovic-Talisman, Jeannine S. McCune, Victoria L. Seewaldt
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Currently, tamoxifen is the only drug approved for reduction of breast cancer risk in premenopausal women. The significant cardiovascular side effects of tamoxifen, coupled with lack of a survival benefit, potential for genotoxicity, and failure to p
Externí odkaz:
https://doaj.org/article/6718832c005c4fdfbdc679acf3cf2f49
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Studies investigating the potential link between adult pre-menopausal obesity [as measured by body mass index (BMI)] and triple-negative breast cancer have been inconsistent. Recent studies show that BMI is not an exact measure of metabolic health; i
Externí odkaz:
https://doaj.org/article/3bb2d9852dfd4ab5ad9801c1ef58b71d