Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Victoria L. Magnuson"'
Publikováno v:
American Journal of Epidemiology. 164:711-724
Several polymorphisms in the vitamin D receptor (VDR ) gene have been reported to be associated with the risk of developing type 1 diabetes, yet published findings have been conflicting. In this study, the authors attempted to evaluate the evidence r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18997463ebb7d523ef99ee7e83310d4
https://doi.org/10.1093/aje/kwj278
https://doi.org/10.1093/aje/kwj278
Publikováno v:
Journal of Biochemical and Biophysical Methods. 60:1-12
Three methods of Single Nucleotide Polymorphism (SNP) detection: SNaPshot, Pyrosequencing and Biplex Invader, with two different chemistries were investigated to compare, (1) accuracy, (2) ease of use, (3) throughput capability, and (4) cost. We geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8c8774f3ad43d7668469256cab9ee0
https://doi.org/10.1016/j.jbbm.2003.11.005
https://doi.org/10.1016/j.jbbm.2003.11.005
Autor:
Richard M. Watanabe, Kerry R. Wiles, Kimberly Colby, Narisu Narisu, Julie A. Douglas, Leonid Segal, Tasha E. Fingerlin, Elizabeth R. Hauser, Pablo Hollstein, Kimberly F. Doheny, Victoria L. Magnuson, Kathleen M. Humphreys, Michael P. Epstein, Soumitra Ghosh, David Rha, Rachel Porter, Jason Tovar, Yong D. Suh, Jaakko Tuomilehto, William Hagopian, Francis S. Collins, Chun Li, Arun M. Unni, Carrie Pfahl, Laura J. Scott, Jason E. Hill, Anabelle Morales-Mena, George Lin, Thomas A. Buchanan, Konstantinos N. Lazaridis, Elizabeth W. Pugh, Peggy P. White, Roshni A. Kasad, Peter S. Chines, Anne U. Jackson, Kristin Patzkowski, Jessica Lambert, Michael R. Erdos, Heather M. Stringham, Timo T. Valle, Richard N. Bergman, Karen L. Mohlke, Kaisa Silander, Christian Welch, William L. Duren, Michael Boehnke
Publikováno v:
Diabetes. 53:821-829
The aim of the Finland-United States Investigation of NIDDM Genetics (FUSION) study is to identify genes that predispose to type 2 diabetes or are responsible for variability in diabetes-related traits via a positional cloning and positional candidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99fe39279d846fe4be56c19556967de
https://doi.org/10.2337/diabetes.53.3.821
https://doi.org/10.2337/diabetes.53.3.821
Autor:
Alyson Witt, Ethan M. Lange, David Rha, William Hagopian, Edna H. Ross, James E. Balow, Catherine Te, Richard M. Watanabe, Heather M. Stringham, Francis S. Collins, Richard C. McEachin, Zarir E. Karanjawala, Elizabeth R. Hauser, William L. Duren, Michael Boehnke, Thomas A. Buchanan, Timo T. Valle, Tasha E. Fingerlin, Richard N. Bergman, Jillian Blaschak-Harvan, Chun Li, Liisa Toivanen, Julie I. Knapp, Victoria L. Magnuson, Gabriele Vidgren, Leonid Segal, Delphine S. Ally, Anjene Musick, Jennie Chang, Stella J. Nylund, Arun M. Unni, Shane A. Shapiro, Peggy P. White, Karen L. Mohlke, Michael P. Epstein, Elza Demirchyan, Ben Shurtleff, Kristina Kudelko, Jaakko Tuomilehto, Joseph B. Rayman, Michael R. Erdos, Hong Shi Kaleta, Eva Tuomilehto-Wolf, Christian Welch, Carl D. Langefeld, Julie A. Douglas, Tiffany Musick, Joyce Tannenbaum, Carrie Pfahl, Ravi Sharaf, Kimmo Kohtamäki, Alistair So, Colin Martin, Jason Tovar, Soumitra Ghosh, Rachel Porter, Peter S. Chines, Edward H. Trager, Johan G. Eriksson, Ray Whiten, Kaisa Silander, Anabelle Morales-Mena, Gunther Birznieks, William Eldridge
Publikováno v:
The American Journal of Human Genetics. 67:1174-1185
We performed a genome scan at an average resolution of 8 cM in 719 Finnish sib pairs with type 2 diabetes. Our strongest results are for chromosome 20, where we observe a weighted maximum LOD score (MLS) of 2.15 at map position 69.5 cM from pter and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0719c412274509a71d4aa0fa1bf5a5df
https://doi.org/10.1016/s0002-9297(07)62948-6
https://doi.org/10.1016/s0002-9297(07)62948-6
Autor:
Richard C. McEachin, Gabriele Vidgren, William Hagopian, Tasha E. Fingerlin, Shane A. Shapiro, Christian Welch, Colin Martin, William L. Duren, Michael Boehnke, Johan G. Eriksson, Gunther Birznieks, William Eldridge, Ray Whiten, Liisa Toivanen, Julie A. Douglas, Zarir E. Karanjawala, Francis S. Collins, Thomas A. Buchanan, Soumitra Ghosh, Carl D. Langefeld, Anjene Musick, Jennie Chang, Stella J. Nylund, Timo T. Valle, Alistair So, Catherine Te, Chun Li, Leonid Segal, Karen L. Mohlke, Carrie Pfahl, Ravi Sharaf, Edna H. Ross, Rachel Porter, Richard M. Watanabe, Joseph B. Rayman, Eva Tuomilehto-Wolf, Elza Demirchyan, David Rha, Joyce Tannenbaum, Victoria L. Magnuson, Elizabeth R. Hauser, Michael P. Epstein, Kimmo Kohtamäki, Richard N. Bergman, Delphine S. Ally, Alyson Witt, Edward H. Trager, Ben Shurtleff, Kristina Kudelko, Jaakko Tuomilehto, Peggy P. White, Julie I. Knapp, Michael R. Erdos, Kaisa Silander, Peter S. Chines, Hong Shi Kaleta, James E. Balow, Christian Ehnholm, Heather M. Stringham, Arun M. Unni, Tiffany Musick, Jason Tovar, Jillian Blaschak-Harvan, Anabelle Morales-Mena, Ethan M. Lange
Publikováno v:
The American Journal of Human Genetics. 67:1186-1200
Type 2 diabetes mellitus is a complex disorder encompassing multiple metabolic defects. We report results from an autosomal genome scan for type 2 diabetes-related quantitative traits in 580 Finnish families ascertained for an affected sibling pair a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60afb82ee87d3b201eb5e4c1a613b7db
https://doi.org/10.1016/s0002-9297(07)62949-8
https://doi.org/10.1016/s0002-9297(07)62949-8
Autor:
Stella J. Nylund, Joseph B. Rayman, Soumitra Ghosh, Lowe Al, Victoria L. Magnuson, Julie I. Knapp, Francis S. Collins, Delphine S. Ally, Zarir E. Karanjawala
Publikováno v:
BioTechniques. 21:700-709
The Applied Biosystems PRISMTM fluorescence-based genotyping system as well as the Invitrogen TA Cloning® vector system are influenced by the tendency of Taq DNA polymerase to add an adenine nucleotide to the 3′ end of PCR products after extension
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2944b9df7f407b86b5fdace2e3839fa
https://doi.org/10.2144/96214rr03
https://doi.org/10.2144/96214rr03
Autor:
Victoria L. Magnuson, Soumitra Ghosh, Francis S. Collins, John D. Carpten, Jeffrey M. Trent, Jeffrey R. Smith, Michael J. Brownstein, Dennis A. Gilbert
Publikováno v:
Genome Research. 5:312-317
Thermostable DNA polymerases can catalyze nontemplated addition of a nucleotide to the 3' end of amplification products. This presents a potential source of error in genotyping studies employing Taq DNA polymerase to amplify microsatellite loci. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a430cc3509c538ccb4f9005bfbbbb53
https://doi.org/10.1101/gr.5.3.312
https://doi.org/10.1101/gr.5.3.312
Publikováno v:
Science. 261:321-327
The role of genetics in male sexual orientation was investigated by pedigree and linkage analyses on 114 families of homosexual men. Increased rates of same-sex orientation were found in the maternal uncles and male cousins of these subjects, but not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4748e05ddff4cf60f0a92dfd2380685
https://doi.org/10.1126/science.8332896
https://doi.org/10.1126/science.8332896
Publikováno v:
Journal of Biological Chemistry. 267:23502-23506
Under substrate adherent conditions, integrin gene expression can be regulated by transforming growth factor-beta, interleukin-1 beta, and prostaglandins. This report demonstrates a new mechanism that can differentially control the expression of seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ca3bcb064a55578814032f4807606a
https://doi.org/10.1016/s0021-9258(18)35867-8
https://doi.org/10.1016/s0021-9258(18)35867-8
Autor:
Jaakko Tuomilehto, Leena Kinnunen, Joel Basken, Cinzia Sarti, Xujing Wang, Victoria L. Magnuson, Matthew W. Klinker, Kaela I. Pearce, Tao Wang, Jennifer J. Schiller, Kerry N. Veth, Valma Harjutsalo, Soumitra Ghosh
Publikováno v:
Immunogenetics. 62(2)
The onset of type 1 diabetes can occur at any age, with as many as half of all cases diagnosed after age 15. Despite this wide distribution in age at diagnosis, most genetic studies focus on cases diagnosed in childhood or during early adulthood. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3381da16f98f42f0248f83a1b0f710f
https://pubmed.ncbi.nlm.nih.gov/20033399
https://pubmed.ncbi.nlm.nih.gov/20033399