Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Victoria L Patterson"'
Autor:
Victoria L Patterson, Alfred J Zullo, Claire Koenig, Sean Stoessel, Hakryul Jo, Xinran Liu, Jinah Han, Murim Choi, Andrew T DeWan, Jean-Leon Thomas, Chia-Yi Kuan, Josephine Hoh
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115789 (2014)
HTRA2, a serine protease in the intermembrane space, has important functions in mitochondrial stress signaling while its abnormal activity may contribute to the development of Parkinson's disease. Mice with a missense or null mutation of Htra2 fail t
Externí odkaz:
https://doaj.org/article/1e839ee060b74e1184e70e61f529d567
Publikováno v:
Birth Defects Res
The RAS signaling pathway regulates cell growth, survival, and differentiation, and its inappropriate activation is associated with disease in humans. The RASopathies, a set of developmental syndromes, arise when the pathway is overactive during deve
Autor:
Gabriel Luna-Arvizu, Daniel T. Grimes, Victoria L. Patterson, Zoe H. Irons, Jodi Schottenfeld-Roames, Rebecca D. Burdine
Publikováno v:
Developmental Biology. 459:79-86
Building a left-right (L-R) asymmetric organ requires asymmetric information. This comes from various sources, including asymmetries in embryo-scale genetic cascades (including the left-sided Nodal cascade), organ-intrinsic mechanical forces, and cel
Autor:
Haixia He, Victoria L. Patterson, Yogesh Goyal, Elizabeth J. Goldsmith, Granton A. Jindal, Eyan Yeung, John M. Humphreys, Rebecca D. Burdine, Stanislav Y. Shvartsman, Kaijia Tian
Publikováno v:
Journal of Biological Chemistry. 292:18814-18820
The MEK1 kinase directly phosphorylates ERK2, after the activation loop of MEK1 is itself phosphorylated by Raf. Studies over the past decade have revealed a large number of disease-related mutations in the MEK1 gene that lead to tumorigenesis and ab
Publikováno v:
Current topics in developmental biology. 124
Cardiac development is a dynamic process regulated by spatial and temporal cues that are integrated to effect molecular, cellular, and tissue-level events that form the adult heart. Disruption of these highly orchestrated events can be devastating fo
Cardiac development is a dynamic process regulated by spatial and temporal cues that are integrated to effect molecular, cellular, and tissue-level events that form the adult heart. Disruption of these highly orchestrated events can be devastating fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8636f8db481ebd1aaeada2aaa588810
https://doi.org/10.1016/bs.ctdb.2016.11.010
https://doi.org/10.1016/bs.ctdb.2016.11.010
Autor:
Shao-Bin Wang, Brian Thompson, Victoria L. Patterson, Bo Chen, Josephine Hoh, Catherine Cherry
Publikováno v:
Journal of visualized experiments : JoVE. (113)
Age-related diseases are becoming increasingly prevalent and the burden continues to grow as our population ages. Effective treatments are necessary to lessen the impact of debilitating conditions but remain elusive in many cases. Only by understandi
Autor:
Alfred J. Zullo, Josephine Hoh, Sean Stoessel, Chia-Yi Kuan, Victoria L. Patterson, Hakryul Jo, Jean-Leon Thomas, Murim Choi, Xinran Liu, Claire M. Koenig, Andrew T. DeWan, Jinah Han
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115789 (2014)
PLoS ONE
PLoS ONE
HTRA2, a serine protease in the intermembrane space, has important functions in mitochondrial stress signaling while its abnormal activity may contribute to the development of Parkinson's disease. Mice with a missense or null mutation of Htra2 fail t
Autor:
Deborah J. Henderson, Caroline J. Formstone, Jennifer N. Murdoch, Zuzanna Lalanne, Sara Wells, Victoria L. Patterson, Dominic P. Norris, Alexander Ermakov, Anju Paudyal, Christine Damrau, Charlotte H. Dean, Xiaowei Lu
Publikováno v:
BMC Developmental Biology, Vol 10, Iss 1, p 87 (2010)
BMC Developmental Biology
Europe PubMed Central
BMC Developmental Biology, 10 (87)
BMC Developmental Biology
Europe PubMed Central
BMC Developmental Biology, 10 (87)
Background The planar cell polarity (PCP) signalling pathway is fundamental to a number of key developmental events, including initiation of neural tube closure. Disruption of the PCP pathway causes the severe neural tube defect of craniorachischisis
Autor:
Debbie Williams, Andy Greenfield, Pam Siggers, Daniel T. Grimes, Michelle Stewart, Benjamin Reeve, Christine Damrau, Jennifer N. Murdoch, Victoria L. Patterson, Anju Paudyal
Publikováno v:
Mechanisms of Development. 126