Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Victoria K Schulman"'
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004880 (2014)
Highlighting the importance of proper intracellular organization, many muscle diseases are characterized by mispositioned myonuclei. Proper positioning of myonuclei is dependent upon the microtubule motor proteins, Kinesin-1 and cytoplasmic Dynein, a
Externí odkaz:
https://doaj.org/article/9930bd8faaaa448a8d6e4a17bbaa1019
Autor:
Jonathan N. Rosen, Mary K. Baylies, David B. Soffar, Victoria K. Schulman, Mafalda Azevedo, Matthew Brendel, Vitaly Boyko
Publikováno v:
The Journal of Cell Biology
Rosen et al. identify a role for the centrosomal protein Bsg25D/Ninein in nuclear positioning and microtubule organization in Drosophila muscle fibers. Genetic, cell biological, and atomic force microscopy analyses demonstrate that complex interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6362f841154d93ce5c9b51a9b6ec7e
https://doi.org/10.1083/jcb.201808176
https://doi.org/10.1083/jcb.201808176
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 4:313-334
In Drosophila melanogaster, the somatic muscle system is first formed during embryogenesis, giving rise to the larval musculature. Later during metamorphosis, this system is destroyed and replaced by an entirely new set of muscles in the adult fly. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980a77424f9058ab0ba2541e9a2b2b44
https://doi.org/10.1002/wdev.180
https://doi.org/10.1002/wdev.180
Publikováno v:
Wiley Interdisciplinary Reviews: Developmental Biology. 4:357-375
The somatic muscle system formed during Drosophila embryogenesis is required for larvae to hatch, feed, and crawl. This system is replaced in the pupa by a new adult muscle set, responsible for activities such as feeding, walking, and flight. Both th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9de30318676379ebea2b770d0ed4ff74
https://doi.org/10.1002/wdev.182
https://doi.org/10.1002/wdev.182
Publikováno v:
Development. 141:355-366
Nuclei are precisely positioned within all cells, and mispositioned nuclei are a hallmark of many muscle diseases. Myonuclear positioning is dependent on Kinesin and Dynein, but interactions between these motor proteins and their mechanisms of action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599331032e4a5e117d85e781d3cb8ad1
https://doi.org/10.1242/dev.095612
https://doi.org/10.1242/dev.095612
Publikováno v:
Fly. 7:193-203
Drosophila melanogaster is a powerful model organism to elucidate basic cellular mechanisms of development. Indeed, much of our understanding of genetic pathways comes from work in Drosophila. However, mutations in many critical genes cause early emb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f29b102124b4e4bc64a6a03bdc3bbb5
https://doi.org/10.4161/fly.25438
https://doi.org/10.4161/fly.25438
Publikováno v:
Methods in Molecular Biology ISBN: 9781493935284
In the skeletal muscle, nuclei are positioned at the periphery of each myofiber and are evenly distributed along its length. Improper positioning of myonuclei has been correlated with muscle disease and decreased muscle function. Several mechanisms r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6597d85af7ba9f5508f6276dace668
https://pubmed.ncbi.nlm.nih.gov/27147050
https://pubmed.ncbi.nlm.nih.gov/27147050
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 12, p e1004880 (2014)
PLoS Genetics, Vol 10, Iss 12, p e1004880 (2014)
Highlighting the importance of proper intracellular organization, many muscle diseases are characterized by mispositioned myonuclei. Proper positioning of myonuclei is dependent upon the microtubule motor proteins, Kinesin-1 and cytoplasmic Dynein, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013a4202227e91814b23cdd1c053ea10
http://europepmc.org/articles/PMC4270490
http://europepmc.org/articles/PMC4270490
Publikováno v:
Wiley interdisciplinary reviews. Developmental biology. 4(4)
The somatic muscle system formed during Drosophila embryogenesis is required for larvae to hatch, feed, and crawl. This system is replaced in the pupa by a new adult muscle set, responsible for activities such as feeding, walking, and flight. Both th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c07f424ce435f201acaee80d8b82c6d
https://pubmed.ncbi.nlm.nih.gov/25728002
https://pubmed.ncbi.nlm.nih.gov/25728002
Publikováno v:
Wiley interdisciplinary reviews. Developmental biology. 4(4)
In Drosophila melanogaster, the somatic muscle system is first formed during embryogenesis, giving rise to the larval musculature. Later during metamorphosis, this system is destroyed and replaced by an entirely new set of muscles in the adult fly. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d03bd71e9bfc8cd0dbfc6c758b84de53
https://pubmed.ncbi.nlm.nih.gov/25758712
https://pubmed.ncbi.nlm.nih.gov/25758712