Výsledky vyhledávání - "Victoria Jewhurst"

AM1-receptor-dependent protection by intermedin of human vascular and cardiac non-vascular cells from ischaemia-reperfusion injury

Autor: David Bell, Victoria Jewhurst, Matthew Ferguson, Liz Donaghy, Anna O’Regan, Mark Harbinson, Malcolm Campbell, Leah Sayers

Publikováno v: The Journal of Physiology. 590:1181-1197

Key points • Coronary artery disease occurs when fatty deposits cause obstruction to blood flow in the coronary arteries, reducing the supply of blood to the heart. This can damage the heart muscle (heart attack). • In this study, a small protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6707d96d120cfbe221048cef9a193a69
https://doi.org/10.1113/jphysiol.2011.221895

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Longitudinal serological surveys of Atlantic salmon, Salmo salar L., using a rapid immunoperoxidase-based neutralization assay for salmonid alphavirus

Autor: H M Rowley, David Graham, Hamish D. Rodger, Daniel Todd, M F McLoughlin, Victoria Jewhurst

Publikováno v: Journal of Fish Diseases. 28:373-379

Longitudinal serological surveys for salmon pancreas disease virus (SPDV), the causal agent of pancreas disease (PD), were conducted on multiple caged populations of Atlantic salmon, Salmo salar L., on two farms over a 77-week period (farm 1, freshwa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b195374673fe0fb836e41560e704576
https://doi.org/10.1111/j.1365-2761.2005.00638.x

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Detection and antigenic characterization of salmonid alphavirus isolates from sera obtained from farmed Atlantic salmon, Salmo salar L., and farmed rainbow trout, Oncorhynchus mykiss (Walbaum)

Autor: H. M. Rowley, Daniel Todd, Jonathan Weston, Victoria Jewhurst, D A Graham, M F McLoughlin, I W Walker

Publikováno v: Journal of Fish Diseases. 27:143-149

A simple method of detecting the presence of the salmonid alphaviruses (SAVs), salmon pancreas disease virus (SPDV) and sleeping disease virus (SDV), from serum samples is described. Using a 96-well tissue-culture plate format, test sera are diluted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e984264616333a084c5d22581ef229c
https://doi.org/10.1111/j.1365-2761.2004.00530.x

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A rapid immunoperoxidase-based virus neutralization assay for salmonid alphavirus used for a serological survey in Northern Ireland

Autor: Daniel Todd, M F McLoughlin, D A Graham, H. M. Rowley, Victoria Jewhurst

Publikováno v: Journal of Fish Diseases. 26:407-413

A modified virus neutralization (VN) assay was developed to replace an existing assay read on the presence or absence of virus-induced cytopathic effect (CPE). The modified assay used a monoclonal antibody to salmon pancreas disease virus as the firs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3439853d8d79642ccf54048f4a0b6b21
https://doi.org/10.1046/j.1365-2761.2003.00472.x

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Comparison of Two Aquatic Alphaviruses, Salmon Pancreas Disease Virus and Sleeping Disease Virus, by Using Genome Sequence Analysis, Monoclonal Reactivity, and Cross-Infection

Autor: Stephane Villoing, Victoria Jewhurst, Jeanette Castric, Michel Brémont, Martin Pfeffer, Joseph Koumans, Jonathan Weston, Marian F. McLoughlin, Daniel Todd, OddMagne Rødseth, Karen Elina Christie

Publikováno v: Journal of Virology. 76:6155-6163

Cell culture isolates of salmon pancreas disease virus (SPDV) of farmed Atlantic salmon and sleeping disease virus (SDV) of rainbow trout were compared. Excluding the poly(A) tracts, the genomic nucleotide sequences of SPDV and SDV RNAs include 11,91

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d854defe85d2dcc2a3fb6b547ae2fbf5
https://doi.org/10.1128/jvi.76.12.6155-6163.2002

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Production and characterisation of monoclonal antibodies to salmon pancreas disease virus

Autor: BJ Borghmans, Jonathan Weston, Welsh, D. Todd, DP Mackie, Victoria Jewhurst, M F McLoughlin, H. M. Rowley

Publikováno v: Diseases of Aquatic Organisms. 46:101-108

Six mouse monoclonal antibodies (mAbs) specific to salmon pancreas disease virus (SPDV) were produced following immunisation with purified virus preparations. These mAbs and 2 mAbs resulting from an earlier investigation were characterised. None of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6706bbc16f2ed8a9bc6b8d91c16173
https://doi.org/10.3354/dao046101

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Characterization of novel circovirus DNAs associated with wasting syndromes in pigs

Autor: Victoria Jewhurst, Daniel Todd, Brian M. Meehan, S. Kennedy, Deborah M. Haines, Lori Hassard, Gordon Allan, Francis McNeilly, Edward G. Clark, John Ellis

Publikováno v: Journal of General Virology. 79:2171-2179

Porcine circovirus (PCV) was initially recognized as a contaminant of continuous pig kidney cell lines and was not thought to be pathogenic. Antibodies reactive to the cell culture isolate of PCV (PCV PK-15) are prevalent in the swine population worl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a496057a060418a3ede1d813e2d38892
https://doi.org/10.1099/0022-1317-79-9-2171

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AM₁-receptor-dependent protection by intermedin of human vascular and cardiac non-vascular cells from ischaemia-reperfusion injury

Autor: David, Bell, Malcolm, Campbell, Matthew, Ferguson, Leah, Sayers, Liz, Donaghy, Anna, O'Regan, Victoria, Jewhurst, Mark, Harbinson

Publikováno v: The Journal of physiology. 590(5)

Intermedin (IMD) protects rodent heart and vasculature from oxidative stress and ischaemia. Less is known about distribution of IMD and its receptors and the potential for similar protection in man. Expression of IMD and receptor components were stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d650f9a289810d1cb96d7dd2a29e652
https://pubmed.ncbi.nlm.nih.gov/22183724

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Nucleotide sequence variation in salmonid alphaviruses from outbreaks of salmon pancreas disease and sleeping disease

Autor: David Graham, H. M. Rowley, Jonathan Weston, H Jewhurst, I W Walker, D. Todd, Victoria Jewhurst, E. J. Branson

Publikováno v: Diseases of aquatic organisms. 66(2)

We compared 18 salmonid alphaviruses (SAV) including the reference F93-125 salmon pancreas disease virus (SPDV) and S49p sleeping disease virus (SDV) isolates by nucleotide sequence analyses of regions within the E1, nsP4 and nsP3 genes, and found th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd6f777cde6a4c0439a4602b1271473
https://pubmed.ncbi.nlm.nih.gov/16231635

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Development and application of a competitive enzyme-linked immunosorbent assay for the detection of serum antibodies to porcine circovirus type 2

Autor: John A. Ellis, Carrie Konoby, Francis McNeilly, Victoria Jewhurst, I. McNair, Gordon Allan, Tiffany S. Cottrell, Brian M. Meehan, I. Walker

Publikováno v: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 12(5)

We report the development of a competitive enzyme-linked immunosorbent assay (c-ELISA) for the detection of antibodies to porcine circovirus type 2 (PCV2), the agent associated with the recently described postweaning multisystemic wasting syndrome in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed2302eb2c8580714da29697344f693
https://pubmed.ncbi.nlm.nih.gov/11021425

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