Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Victoria J. Cookson"'
Autor:
Sheila E. Francis, Charlotte K. Moore, Victoria J. Cookson, Diane V. Lefley, Russell Hughes, Paul R. Heath, Catherine A. Evans, Amy R. Spicer-Hadlington, Khawla Ahmed, A. Graham Pockley, Jayakumar Vadakekolathu, Ana E. Amariutei, Penelope D. Ottewell, Emmanuel Pinteaux, Lewis A. Quayle, Claudia Tulotta
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
NPJ Breast Cancer
npj Breast Cancer
NPJ Breast Cancer
npj Breast Cancer
Breast cancer bone metastasis is currently incurable, ~75% of patients with late-stage breast cancer develop disease recurrence in bone and available treatments are only palliative. We have previously shown that production of the pro-inflammatory cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee4edcf7cfd90ae70dfe6caa0dfa98a
https://doaj.org/article/db7c85c82ea947e69d237a3402f52c96
https://doaj.org/article/db7c85c82ea947e69d237a3402f52c96
Autor:
Walter M Gregory, Victoria J. Cookson, K Freeman, Andrew M. Hanby, Ingunn Holen, X Liu, Amy R. Spicer-Hadlington, Gloria Allocca, L Hambley, Claudia Tulotta, Diane V. Lefley, Robert E. Coleman, Penelope D. Ottewell, M Kruithof de-Julio, Janet E. Brown, Steven Bradbury
Publikováno v:
Cancer Research. 79:P1-05
Background: Breast cancer bone metastases are incurable and new therapeutic targets needed. After homing and colonising bone, cancer cells remain dormant, until signals from the microenvironment stimulate their proliferation to form overt metastases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c848fdde8b17c58dcb7d44e851f3e9c2
https://doi.org/10.1158/1538-7445.sabcs18-p1-05-01
https://doi.org/10.1158/1538-7445.sabcs18-p1-05-01
Autor:
J. Mark Wilkinson, Robert E. Coleman, Steven Bradbury, Katy Freeman, Andrew M. Hanby, Penelope D. Ottewell, Ingunn Holen, Amy R. Spicer-Hadlington, Diane V. Lefley, Walter M Gregory, Faith Nutter, Janet E. Brown, Victoria J. Cookson, Gloria Allocca, Claudia Tulotta, Lisa Hambley, Xinming Liu, Paul R. Heath, Marianna Kruithof-de Julio
Purpose: Breast cancer bone metastases are incurable, highlighting the need for new therapeutic targets. After colonizing bone, breast cancer cells remain dormant, until signals from the microenvironment stimulate outgrowth into overt metastases. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb0ba6f0788d187034678ad2f101c1d
Autor:
Steve J. Webster, Averil Y. Warren, Raheela N. Khan, Neil Chapman, Saurabh V. Gandhi, Sarah L. Waite, G. Nicholas Europe-Finner, Victoria J. Cookson
Publikováno v:
Journal of Biological Chemistry. 288:6704-6716
The onset of parturition is associated with a number of proinflammatory mediators that are themselves regulated by the nuclear factor κB (NF-κB) family of transcription factors. In this context, we previously reported that the RelA NF-κB subunit r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd0fa1f8d75f961657e5da353be82cd7
https://doi.org/10.1074/jbc.m112.440602
https://doi.org/10.1074/jbc.m112.440602
Autor:
Caroline A. Green, Eldo T. Verghese, Victoria J. Cookson, Valerie Speirs, Thomas A. Hughes, Steven Pollock, Alison Waterworth, R H Partanen, Jo Howarth, Andrew M. Hanby, HG Shenoy
Publikováno v:
Histopathology. 59:609-618
Verghese E T, Shenoy H, Cookson V J, Green C A, Howarth J, Partanen R H, Pollock S, Waterworth A, Speirs V, Hughes T A & Hanby A M (2011) Histopathology59, 609–618 Epithelial–mesenchymal interactions in breast cancer: evidence for a role of nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58a8ab4f90efd8584b77ff0d3b4ad563
https://doi.org/10.1111/j.1365-2559.2011.03917.x
https://doi.org/10.1111/j.1365-2559.2011.03917.x
Autor:
Neil Chapman, Sarah L. Waite, Paul R. Heath, Paul J. Hurd, Victoria J. Cookson, Saurabh V. Gandhi
Publikováno v:
Molecular human reproduction. 21(11)
Human parturition is associated with many pro-inflammatory mediators which are regulated by the nuclear factor-kappaB (NF-κB) family of transcription factors. In the present study, we employed a ChIP-on-chip approach to define genomic loci within ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609c2d7f55c49be25ce6be1b8f84c102
https://pubmed.ncbi.nlm.nih.gov/26405173
https://pubmed.ncbi.nlm.nih.gov/26405173
Autor:
Victoria J. Cookson, Ewan E. Morrison, Heather L. Martin, Darren C. Tomlinson, Matthew Adams, Jacquelyn Bond, Sandra M. Bell, Julie Higgins
Publikováno v:
Journal of biomolecular screening. 19(1)
Premature chromosome condensation (PCC) is a consequence of early mitotic entry, where mitosis begins before completion of DNA replication. Previously we have identified mutations in MCPH1, a DNA damage response and potential tumor suppressor gene, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293c66f71c762781982907b917f81b88
https://pubmed.ncbi.nlm.nih.gov/23983231
https://pubmed.ncbi.nlm.nih.gov/23983231
Autor:
Steve J, Webster, Sarah L, Waite, Victoria J, Cookson, Averil, Warren, Raheela, Khan, Saurabh V, Gandhi, G Nicholas, Europe-Finner, Neil R, Chapman
Publikováno v:
The Journal of biological chemistry. 288(9)
The onset of parturition is associated with a number of proinflammatory mediators that are themselves regulated by the nuclear factor κB (NF-κB) family of transcription factors. In this context, we previously reported that the RelA NF-κB subunit r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92c5817502c53244b7bf7687d8d9f2b3
https://pubmed.ncbi.nlm.nih.gov/23297421
https://pubmed.ncbi.nlm.nih.gov/23297421
Autor:
Thomas A. Hughes, Bruce E. Hayward, Brian Hogan, Michael A. Bentley, Victoria J. Cookson, Kieran Horgan, Lee Hazelwood
Publikováno v:
Cellular oncology (Dordrecht). 35(4)
Extra-cellular microRNAs have been identified within blood and their profiles reflect various pathologies; therefore they have potential as disease biomarkers. Our aim was to investigate how circulating microRNA profiles change during cancer treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f162cf50cd082e9feb49b53a17fcb21
https://pubmed.ncbi.nlm.nih.gov/22821209
https://pubmed.ncbi.nlm.nih.gov/22821209
Autor:
Eldo T, Verghese, Hrishikesh, Shenoy, Victoria J, Cookson, Caroline A, Green, Jo, Howarth, R H, Partanen, Steven, Pollock, Alison, Waterworth, Valerie, Speirs, Thomas A, Hughes, Andrew M, Hanby
Publikováno v:
Histopathology. 59(4)
Characteristics of the stroma around tumours are critical in defining the behaviour of cancers. β-Catenin is well established as a critical regulator of carcinogenesis, acting as a transcriptional co-activator in the nuclei of epithelial cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93dea867d39286e62937a07cdc260e29
https://pubmed.ncbi.nlm.nih.gov/22014042
https://pubmed.ncbi.nlm.nih.gov/22014042