Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Victoria J Bartlett"'
Autor:
Maria C. Foss-Freitas, Baris Akinci, Adam Neidert, Victoria J. Bartlett, Eunju Hurh, Ewa Karwatowska-Prokopczuk, Elif A. Oral
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Familial partial lipodystrophy (FPLD) is a rare disease characterized by selective loss of peripheral subcutaneous fat, associated with dyslipidemia and diabetes mellitus. Reductions in circulating levels of ANGPTL3 are associated
Externí odkaz:
https://doaj.org/article/50ffdd79d6e14f6093c4b51acb7bcb51
Autor:
Victoria J Bartlett, Eunju Hurh, Elif Arioglu Oral, Adam H. Neidert, Ewa Karwatowska-Prokopczuk, Baris Akinci, Maria C Foss-Freitas
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-12 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background Familial partial lipodystrophy (FPLD) is a rare disease characterized by selective loss of peripheral subcutaneous fat, associated with dyslipidemia and diabetes mellitus. Reductions in circulating levels of ANGPTL3 are associated with low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c02b87ec1f624c5136d88267c15fe1e
https://doaj.org/article/50ffdd79d6e14f6093c4b51acb7bcb51
https://doaj.org/article/50ffdd79d6e14f6093c4b51acb7bcb51
Autor:
Jean-Claude Tardif, Ewa Karwatowska-Prokopczuk, Eric St Amour, Christie M Ballantyne, Michael D Shapiro, Patrick M Moriarty, Seth J Baum, Eunju Hurh, Victoria J Bartlett, Joyce Kingsbury, Amparo L Figueroa, Veronica J Alexander, Joseph Tami, Joseph L Witztum, Richard S Geary, Louis St L O’Dea, Sotirios Tsimikas, Daniel Gaudet
Publikováno v:
European heart journal, vol 43, iss 14
Aims Hypertriglyceridaemia is associated with increased risk of cardiovascular events. This clinical trial evaluated olezarsen, an N-acetyl-galactosamine-conjugated antisense oligonucleotide targeted to hepatic APOC3 mRNA to inhibit apolipoprotein C-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab435f70ddb9874ac3d5d38b0c089f7
https://escholarship.org/uc/item/52k3p81s
https://escholarship.org/uc/item/52k3p81s
Autor:
Joyce Kingsbury, Amparo L Figueroa, Joseph L. Witztum, Walter Singleton, Louis O'Dea, Daniel Gaudet, Philip Piscitelli, Ewa Karwatowska-Prokopczuk, Sotirios Tsimikas, Seth J. Baum, Vupanorsen Study Investigators, Eunju Hurh, Richard S. Geary, Victoria J Bartlett
Publikováno v:
European heart journal. 41(40)
Aims Loss-of-function mutations in ANGPTL3 are associated with beneficial effects on lipid and glucose metabolism and reduced risk of coronary artery disease. Vupanorsen (AKCEA-ANGPTL3-L Rx ) is an N-acetyl galactosamine-conjugated antisense oligonuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d8978c500090731b0e3ffaefedd11a
https://pubmed.ncbi.nlm.nih.gov/33170930
https://pubmed.ncbi.nlm.nih.gov/33170930
Autor:
Mark Grier, Michael Draper, Caroline Dudley, Peter J. Donovan, Oak K. Kim, Kevin A. Klausner, Victoria J. Bartlett, S. Ken Tanaka, Michael N. Alekshun, Stuart B. Levy, Lynne Garrity-Ryan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3380-3383
ExsA is a multiple adaptational response (MAR) transcription factor, regulating the expression of a virulence determinant, the type III secretion system (T3SS) in Pseudomonas aeruginosa. Non-cytotoxic, non-antibacterial N-hydroxybenzimidazoles were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8be65f7737be644a80b5d301b11471
https://doi.org/10.1016/j.bmcl.2010.04.014
https://doi.org/10.1016/j.bmcl.2010.04.014
Autor:
Michael N. Alekshun, Ann B. Macone, Atul K. Verma, S. Ken Tanaka, Mark Grier, Victoria J. Bartlett, Oak K. Kim, J. Donatelli, Lynne Garrity-Ryan, Stuart B. Levy, Gabriel Medjanis
Publikováno v:
Journal of Medicinal Chemistry. 52:5626-5634
LcrF, a Multiple Adaptational Response (MAR) transcription factor, regulates virulence in Yersinia pestis and Yersinia pseudotuberculosis. In a search for small molecule inhibitors of LcrF, an acrylic amide series of N-hydroxybenzimidazoles was synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18f4cd74e15c6fe85f519b47a59d6b9
https://doi.org/10.1021/jm9006577
https://doi.org/10.1021/jm9006577
Autor:
Mark Grier, Michael N. Alekshun, Atul K. Verma, Victoria J. Bartlett, Todd Bowser, Taduesz Warchol, Stuart B. Levy
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5652-5655
Structure-based drug design was utilized to identify potent small-molecule inhibitors of proteins within the AraC family of bacterial transcription factors, which control virulence in medically important microbes. These agents represent a novel appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9715f266fc64f23166710626be2c55
https://doi.org/10.1016/j.bmcl.2007.07.072
https://doi.org/10.1016/j.bmcl.2007.07.072
Autor:
Victoria J. Bartlett, Oak K. Kim, Joan Mecsas, Warangkhana Songsungthong, S. Ken Tanaka, Atul K. Verma, Cynthia Castillo, Michael N. Alekshun, Joan-Miquel Balada-Llasat, Michael L. Fisher, Lynne Garrity-Ryan, Stuart B. Levy
LcrF (VirF), a transcription factor in the multiple adaptational response (MAR) family, regulates expression of the Yersinia type III secretion system (T3SS). Yersinia pseudotuberculosis lcrF -null mutants showed attenuated virulence in tissue cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9df339dd20871b55dfdf24ba292875
https://europepmc.org/articles/PMC2976336/
https://europepmc.org/articles/PMC2976336/
Autor:
Oak K. Kim, Lynne K. Garrity-Ryan, Victoria J. Bartlett, Mark C. Grier, Atul K. Verma, Gabriel Medjanis, Janice E. Donatelli, Ann B. Macone, S. Ken Tanaka, Stuart B. Levy, Michael N. Alekshun
Publikováno v:
Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 18, p5626-5634, 9p