Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Victoria J, Heath"'
Autor:
Camille Huser, Barry A. Gusterson, Howard Kendrick, Victoria J. Heath, Torsten Stein, Diane Crighton, Kevin M. Ryan, Alexandra K. Bell, Marie Anne Pringle, Matthew J. Smalley
Publikováno v:
Cell Death & Differentiation. 17:304-315
Transforming growth factor beta (TGFbeta)-stimulated clone-22 domain family member 1 (TSC-22D1) has previously been associated with enhanced apoptosis in several cell systems. In an attempt to identify novel factors that are involved in the control o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d62723706521b25e38b997ada6fac7
https://doi.org/10.1038/cdd.2009.126
https://doi.org/10.1038/cdd.2009.126
Autor:
Torsten Stein, Alexandra K. Bell, Stephen J. Weber-Hall, Victoria J. Heath, Marie Anne Pringle, Joanna S. Morris, Roderick K. Ferrier, Barry A. Gusterson, Claire R. Davies
Publikováno v:
Journal of Cellular Physiology. 206:16-24
Mammary morphogenesis in the mouse is driven by specialized structures at the ends of the developing ducts, the terminal end buds (TEB). The mechanisms controlling the precise branching and spacing of the ducts are, as yet, unknown. To identify genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7b6a4accdc6f8690a8fb92351ad625
https://doi.org/10.1002/jcp.20427
https://doi.org/10.1002/jcp.20427
Autor:
Marco Merlano, Milena Gasco, Tim Crook, Louise Hiller, Alberto Comino, Paul R. Smith, Daniele Bergamaschi, Alexandra Sullivan, Xin Lu, Nelofer Syed, Isik G. Yulug, Giuseppe Trigiante, Barry A. Gusterson, Victoria J. Heath, Paul J. Farrell, Alexandra K. Bell, Marlene Attard, Olivier Reelfs, Gianmauro Numico, Mahvash Tavassoli
Publikováno v:
Cancer Cell
Intact p73 function is shown to be an important determinant of cellular sensitivity to anticancer agents. Inhibition of p73 function by dominant-negative proteins or by mutant p53 abrogates apoptosis and cytotoxicity induced by these agents. A polymo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fb5b287b2fb0b1e8f55006109ea0ac
https://doi.org/10.1016/s1535-6108(03)00079-5
https://doi.org/10.1016/s1535-6108(03)00079-5
Publikováno v:
Experimental Cell Research. 254:91-98
The nuclear oncoprotein Myc is a pivotal regulator of several important biological processes, including cellular proliferation, differentiation, and apoptosis. Deregulated Myc expression is incompatible with terminal differentiation in a variety of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7a40b56f73b423aa8124e586ba3b19
https://doi.org/10.1006/excr.1999.4736
https://doi.org/10.1006/excr.1999.4736
Autor:
Mary M. Bendig, Catherine A. Kettleborough, Jose Saldanha, Charlotte J. Morrison, Victoria J. Heath
Publikováno v:
"Protein Engineering, Design and Selection". 4:773-783
A mouse monoclonal antibody (mAb 425) with therapeutic potential was 'humanized' in two ways. Firstly the mouse variable regions from mAb 425 were spliced onto human constant regions to create a chimeric 425 antibody. Secondly, the mouse complementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b132a8fe383b903f87469bb4d1b2dc
https://doi.org/10.1093/protein/4.7.773
https://doi.org/10.1093/protein/4.7.773
Autor:
Gareth J. Inman, Diane Crighton, Camille Huser, Victoria J. Heath, Barry A. Gusterson, Torsten Stein, M-A Pringle, Alexandra K. Bell, Kevin M. Ryan
Publikováno v:
Breast Cancer Research : BCR
Mammary gland involution is characterised by a high degree of apoptosis. By identifying genes that are upregulated at this developmental stage, we aimed to discover key factors that are involved in the induction of mammary epithelial cell death and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a787d5a84698dbd6472ad1a7a19fe3
https://doi.org/10.1186/bcr1901
https://doi.org/10.1186/bcr1901
Autor:
Joanna S, Morris, Torsten, Stein, Marie-Anne, Pringle, Claire R, Davies, Stephen, Weber-Hall, Roderick K, Ferrier, Alexandra K, Bell, Victoria J, Heath, Barry A, Gusterson
Publikováno v:
Journal of cellular physiology. 206(1)
Mammary morphogenesis in the mouse is driven by specialized structures at the ends of the developing ducts, the terminal end buds (TEB). The mechanisms controlling the precise branching and spacing of the ducts are, as yet, unknown. To identify genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c53d893395902da144020c26b8568b76
https://pubmed.ncbi.nlm.nih.gov/15920758
https://pubmed.ncbi.nlm.nih.gov/15920758
Publikováno v:
Breast Cancer Research
Recent publications have classified breast cancers on the basis of expression of cytokeratin-5 and -17 at the RNA and protein levels, and demonstrated the importance of these markers in defining sporadic tumours with bad prognosis and an association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e739b7ca293f0e3ab867717ea5a390
https://doi.org/10.1186/bcr1041
https://doi.org/10.1186/bcr1041
Autor:
Claire R. Davies, Joanna S. Morris, Victoria J. Heath, Barry A. Gusterson, Roderick K. Ferrier, Torsten Stein, G. P. Sandilands, Marie-Anne Duffy, Alexandra K. Bell, Stephen J. Weber-Hall
Publikováno v:
Breast Cancer Research. 6:R75
Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process. We used Affymetrix oligonucleotide microarrays to perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1972e3461658d090d9fce2b64c8af70d
https://doi.org/10.1186/bcr753
https://doi.org/10.1186/bcr753