Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Victoria J, DeRose"'
Autor:
Hannah C. Pigg, Matthew V. Yglesias, Emily C. Sutton, Christine E. McDevitt, Michael Shaw, Victoria J. DeRose
Publikováno v:
ACS chemical biology. 17(8)
The properties of small molecule Pt(II) compounds that drive specific cellular responses are of interest due to their broad clinical use as chemotherapeutics as well as to provide a better mechanistic understanding of bioinorganic processes. The chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5113f591bd5b694cd97974985c8782c0
https://pubmed.ncbi.nlm.nih.gov/35917257
https://pubmed.ncbi.nlm.nih.gov/35917257
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(14)
Oxaliplatin, a platinum compound in broad clinical use, can induce cell death through a nucleolar stress pathway rather than the canonical DNA damage response studied for other Pt(II) compounds. Previous work has found that the oxaliplatin 1,2-diamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104073d11446172f1137af4cd74773d0
https://pubmed.ncbi.nlm.nih.gov/35475312
https://pubmed.ncbi.nlm.nih.gov/35475312
Autor:
Laura M, Hunsicker-Wang, Matthew J, Vogt, Charles G, Hoogstraten, Nathaniel J, Cosper, Audrey M, Davenport, Christopher H, Hendon, Robert A, Scott, R David, Britt, Victoria J, DeRose
Publikováno v:
Journal of inorganic biochemistry. 230
Phosphorothioate modifications have widespread use in the field of nucleic acids. As substitution of sulfur for oxygen can alter metal coordination preferences, the phosphorothioate metal-rescue experiment is a powerful method for identifying metal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::316bea0bda3bbf6cc8c51f456d7a2d0e
https://pubmed.ncbi.nlm.nih.gov/35219138
https://pubmed.ncbi.nlm.nih.gov/35219138
Autor:
Victoria J. DeRose, Sarah L. J. Michel
Publikováno v:
Current Opinion in Chemical Biology. 55:A4-A6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497a63ff286b9c57a46b6416ff032e04
https://doi.org/10.1016/j.cbpa.2020.03.002
https://doi.org/10.1016/j.cbpa.2020.03.002
Autor:
Min Chieh Yang, Emily C. Sutton, Victoria J. DeRose, Jack Y Prochnau, Christine E. McDevitt, Matthew V. Yglesias, Christopher H. Hendon, Austin M. Mroz, Rachael M. Cunningham
Publikováno v:
J Am Chem Soc
Platinum(II) compounds are a critical class of chemotherapeutic agents. Recent studies have highlighted the ability of a subset of Pt(II) compounds, including oxaliplatin but not cisplatin, to induce cytotoxicity via nucleolar stress rather than a ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1999d388410a9b3a6dad4c58a08f5e26
https://doi.org/10.1021/jacs.9b10319
https://doi.org/10.1021/jacs.9b10319
Autor:
Laura M. Hunsicker-Wang, Matthew J. Vogt, Charles G. Hoogstraten, Nathaniel J. Cosper, Audrey M. Davenport, Christopher H. Hendon, Robert A. Scott, R. David Britt, Victoria J. DeRose
Publikováno v:
Journal of Inorganic Biochemistry. 230:111754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989112780479eeba5448713c00720463
https://doi.org/10.1016/j.jinorgbio.2022.111754
https://doi.org/10.1016/j.jinorgbio.2022.111754
Publikováno v:
Comprehensive Coordination Chemistry III ISBN: 9780081026892
Comprehensive Coordination Chemistry III
Comprehensive Coordination Chemistry III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9da295a840094818dd9efc640a809fe
https://doi.org/10.1016/b978-0-08-102688-5.00112-4
https://doi.org/10.1016/b978-0-08-102688-5.00112-4
Publikováno v:
J Inorg Biochem
Identifying the interactions of small molecules with biomolecules in complex cellular environments is a significant challenge. As one important example, despite being widely used for decades, much is still not understood regarding the cellular target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24e4e50c7b437742c8379c574f45a80
https://doi.org/10.1016/j.jinorgbio.2018.09.007
https://doi.org/10.1016/j.jinorgbio.2018.09.007
Autor:
Emily C. Sutton, Christopher H. Hendon, Matthew V. Yglesias, Min Chieh Yang, Victoria J. DeRose, Christine E. McDevitt, Austin M. Mroz
Publikováno v:
J Biol Inorg Chem
Platinum anticancer therapeutics are widely used in a variety of chemotherapy regimens. Recent work has revealed that the cytotoxicity of oxaliplatin and phenanthriplatin is through induction of ribosome biogenesis stress pathways, differentiating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b3404d44d215dfd45058e06d129802
https://pubmed.ncbi.nlm.nih.gov/31494760
https://pubmed.ncbi.nlm.nih.gov/31494760
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795151c117ab764280880b01ebbf0961
https://doi.org/10.1096/fasebj.2019.33.1_supplement.471.17
https://doi.org/10.1096/fasebj.2019.33.1_supplement.471.17