Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Victoria I, Bunik"'
Autor:
Victoria I. Bunik
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/798316d8703b4603a7127ff76953728f
Autor:
Victoria I. Bunik
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1342 (2024)
In recent decades, biology has made tremendous progress in the high-throughput analytic and genetic techniques used to characterize the molecular components of living cells and their interactions [...]
Externí odkaz:
https://doaj.org/article/242baa54be774e7ba7ba9e7ad13f59e2
Autor:
Victoria I. Bunik
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/9ecf50587f044a338d3e633a590d728e
Autor:
Adelheid Weidinger, Nadja Milivojev, Arthur Hosmann, J. Catharina Duvigneau, Csaba Szabo, Gabor Törö, Laurin Rauter, Annette Vaglio-Garro, Garik V. Mkrtchyan, Lidia Trofimova, Rinat R. Sharipov, Alexander M. Surin, Irina A. Krasilnikova, Vsevolod G. Pinelis, Laszlo Tretter, Rudolf Moldzio, Hülya Bayır, Valerian E. Kagan, Victoria I. Bunik, Andrey V. Kozlov
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102669- (2023)
Brain injury is accompanied by neuroinflammation, accumulation of extracellular glutamate and mitochondrial dysfunction, all of which cause neuronal death. The aim of this study was to investigate the impact of these mechanisms on neuronal death.Pati
Externí odkaz:
https://doaj.org/article/427e252d29b84f7382a2fca0e3a2b261
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Amino acid deprivation therapy (AADT) is a promising strategy for developing novel anticancer treatments, based on variations in metabolism of healthy and malignant cells. L-asparaginase was the first amino acid-degrading enzyme that received FDA app
Externí odkaz:
https://doaj.org/article/761bf584c1f2452095cab24c7a8f2711
Autor:
Victoria I. Bunik, Claudine Habak
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/3b4206675ac248e89d107b4d9e9b2fcf
Autor:
Alexandra I. Boyko, Irina S. Karlina, Lev G. Zavileyskiy, Vasily A. Aleshin, Artem V. Artiukhov, Thilo Kaehne, Alexander L. Ksenofontov, Sergey I. Ryabov, Anastasia V. Graf, Angela Tramonti, Victoria I. Bunik
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundThe DHTKD1-encoded 2-oxoadipate dehydrogenase (OADH) oxidizes 2-oxoadipate—a common intermediate of the lysine and tryptophan catabolism. The mostly low and cell-specific flux through these pathways, and similar activities of OADH and ubi
Externí odkaz:
https://doaj.org/article/c348e03e0bc340388c2b955d9ea9932f
Autor:
Victoria I. Bunik, Artem V. Artiukhov, Alexey V. Kazantsev, Vasily A. Aleshin, Alexandra I. Boyko, Alexander L. Ksenofontov, Nikolay V. Lukashev, Anastasia V. Graf
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
In vitro and in cell cultures, succinyl phosphonate (SP) and adipoyl phosphonate (AP) selectively target dehydrogenases of 2-oxoglutarate (OGDH, encoded by OGDH/OGDHL) and 2-oxoadipate (OADH, encoded by DHTKD1), respectively. To assess the selectivit
Externí odkaz:
https://doaj.org/article/ae420945964148f7aeda0e9e80f8ae1c
Autor:
Natalia V. Balashova, Lev G. Zavileyskiy, Artem V. Artiukhov, Leonid A. Shaposhnikov, Olga P. Sidorova, Vladimir I. Tishkov, Angela Tramonti, Anastasia A. Pometun, Victoria I. Bunik
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Oxidized nicotinamide adenine dinucleotide (NAD+) is a biological molecule of systemic importance. Essential role of NAD+ in cellular metabolism relies on the substrate action in various redox reactions and cellular signaling. This work introduces an
Externí odkaz:
https://doaj.org/article/7c51da80f9bf48feafbe67a19e643485
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Thiamine (vitamin B1) is often deficient in oncopatients, particularly those undergoing chemotherapy. However, interaction between the thiamine deficiency and anticancer action of drugs has not been characterized. A major natural thiamine derivative,
Externí odkaz:
https://doaj.org/article/fdd9f6281b3f4074abbe596232817695