Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Victoria H Mann"'
Autor:
Sujittra Chaiyadet, Sirikachorn Tangkawattana, Michael J Smout, Wannaporn Ittiprasert, Victoria H Mann, Raksawan Deenonpoe, Patpicha Arunsan, Alex Loukas, Paul J Brindley, Thewarach Laha
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010839 (2022)
Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor for cholangiocarcinoma (CCA) in the Mekong Basin countries of Thailand, Lao PDR, Vietnam, Myanmar and Cambodia. Using a novel model of CCA, involving infect
Externí odkaz:
https://doaj.org/article/fdd882f39a254d7a85d1ab254586a92d
Autor:
Benjamin J Hulme, Kathrin K Geyer, Josephine E Forde-Thomas, Gilda Padalino, Dylan W Phillips, Wannaporn Ittiprasert, Shannon E Karinshak, Victoria H Mann, Iain W Chalmers, Paul J Brindley, Cornelis H Hokke, Karl F Hoffmann
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1009828 (2022)
α-galactosidase (α-GAL) and α-N-acetylgalactosaminidase (α-NAGAL) are two glycosyl hydrolases responsible for maintaining cellular homeostasis by regulating glycan substrates on proteins and lipids. Mutations in the human genes encoding either en
Externí odkaz:
https://doaj.org/article/05828ee02d5c4a1e99b9770422f25c16
Autor:
Michael Smith, Swara Yadav, Olayemi G Fagunloye, Nana Adjoa Pels, Daniel A Horton, Nashwah Alsultan, Andrea Borns, Carolyn Cousin, Freddie Dixon, Victoria H Mann, Clarence Lee, Paul J Brindley, Najib M El-Sayed, Joanna M Bridger, Matty Knight
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009094 (2021)
BackgroundSchistosomiasis remains widespread in many regions despite efforts at its elimination. By examining changes in the transcriptome at the host-pathogen interface in the snail Biomphalaria glabrata and the blood fluke Schistosoma mansoni, we p
Externí odkaz:
https://doaj.org/article/347e2f90ad1d4bc2b77c6bda5239d9af
Autor:
Wannaporn Ittiprasert, Victoria H Mann, Shannon E Karinshak, Avril Coghlan, Gabriel Rinaldi, Geetha Sankaranarayanan, Apisit Chaidee, Toshihiko Tanno, Chutima Kumkhaek, Pannathee Prangtaworn, Margaret M Mentink-Kane, Christina J Cochran, Patrick Driguez, Nancy Holroyd, Alan Tracey, Rutchanee Rodpai, Bart Everts, Cornelis H Hokke, Karl F Hoffmann, Matthew Berriman, Paul J Brindley
Publikováno v:
eLife, Vol 8 (2019)
CRISPR/Cas9-based genome editing has yet to be reported in species of the Platyhelminthes. We tested this approach by targeting omega-1 (ω1) of Schistosoma mansoni as proof of principle. This secreted ribonuclease is crucial for Th2 polarization and
Externí odkaz:
https://doaj.org/article/b44d0fcb161541f696572c51b67e0c12
Autor:
Patpicha Arunsan, Wannaporn Ittiprasert, Michael J Smout, Christina J Cochran, Victoria H Mann, Sujittra Chaiyadet, Shannon E Karinshak, Banchob Sripa, Neil David Young, Javier Sotillo, Alex Loukas, Paul J Brindley, Thewarach Laha
Publikováno v:
eLife, Vol 8 (2019)
Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor (IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2012) for cholangiocarcinoma (CCA) in the Lower Mekong River Basin countries includin
Externí odkaz:
https://doaj.org/article/396bc5f294004fa185c635a8aa2ab358
Autor:
Apisit Chaidee, Sudarat Onsurathum, Kitti Intuyod, Patchareewan Pannangpetch, Chatlert Pongchaiyakul, Porntip Pinlaor, Chawalit Pairojkul, Wannaporn Ittiprasert, Christina J Cochran, Victoria H Mann, Paul J Brindley, Somchai Pinlaor
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 6, p e0006611 (2018)
Complications arising from infection with the carcinogenic liver fluke Opisthorchis viverrini cause substantial morbidity and mortality in Thailand and adjacent lower Mekong countries. In parallel, the incidence rate of diabetes mellitus (DM) is incr
Externí odkaz:
https://doaj.org/article/f83ccd8fffc04fa6a9212c1ce22e489e
Autor:
Samantha N McNulty, Jose F Tort, Gabriel Rinaldi, Kerstin Fischer, Bruce A Rosa, Pablo Smircich, Santiago Fontenla, Young-Jun Choi, Rahul Tyagi, Kymberlie Hallsworth-Pepin, Victoria H Mann, Lakshmi Kammili, Patricia S Latham, Nicolas Dell'Oca, Fernanda Dominguez, Carlos Carmona, Peter U Fischer, Paul J Brindley, Makedonka Mitreva
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006537 (2017)
Food borne trematodes (FBTs) are an assemblage of platyhelminth parasites transmitted through the food chain, four of which are recognized as neglected tropical diseases (NTDs). Fascioliasis stands out among the other NTDs due to its broad and signif
Externí odkaz:
https://doaj.org/article/883fbd5b5c5b4000bf2b0b4b8bee7375
Autor:
Sutas Suttiprapa, Gabriel Rinaldi, Isheng J Tsai, Victoria H Mann, Larisa Dubrovsky, Hong-Bin Yan, Nancy Holroyd, Thomas Huckvale, Caroline Durrant, Anna V Protasio, Tatiana Pushkarsky, Sergey Iordanskiy, Matthew Berriman, Michael I Bukrinsky, Paul J Brindley
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005931 (2016)
Schistosomiasis is the most important helminthic disease of humanity in terms of morbidity and mortality. Facile manipulation of schistosomes using lentiviruses would enable advances in functional genomics in these and related neglected tropical dise
Externí odkaz:
https://doaj.org/article/1f00e14133d744a8928a8c41a4c3c2a2
Autor:
Ana E Zeraik, Gabriel Rinaldi, Victoria H Mann, Anastas Popratiloff, Ana P U Araujo, Ricardo Demarco, Paul J Brindley
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2602 (2013)
Septins are a family of eukaryotic GTP binding proteins conserved from yeasts to humans. Originally identified in mutants of budding yeast, septins participate in diverse cellular functions including cytokinesis, organization of actin networks, cell
Externí odkaz:
https://doaj.org/article/126c080a82464066a64b85920b4770c7
Autor:
Gabriel Rinaldi, Sabine E Eckert, Isheng J Tsai, Sutas Suttiprapa, Kristine J Kines, José F Tort, Victoria H Mann, Daniel J Turner, Matthew Berriman, Paul J Brindley
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002820 (2012)
Functional studies will facilitate characterization of role and essentiality of newly available genome sequences of the human schistosomes, Schistosoma mansoni, S. japonicum and S. haematobium. To develop transgenesis as a functional approach for the
Externí odkaz:
https://doaj.org/article/420675da718e475b97585bd56cfbe2f5