Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Victoria H Mann"'
Multiplexed CRISPR-Cas9 protocol for large transgene integration into the Schistosoma mansoni genome
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102886- (2024)
Summary: Precise, on-target CRISPR-Cas9 genome editing has been shown in Schistosoma mansoni, involving both non-homology end joining and homology-directed repair pathways. Here, we present a multiplexed CRISPR-Cas9 protocol for large transgene integ
Externí odkaz:
https://doaj.org/article/947dbf2ecd4345ddb2695b0559821e80
Autor:
Rutchanee Rodpai, Vor Luvira, Lakkhana Sadaow, Wattana Sukeepaisarnjaroen, Amnat Kitkhuandee, Krisada Paonariang, Oranuch Sanpool, Wannaporn Ittiprasert, Victoria H. Mann, Pewpan M. Intapan, Paul J. Brindley, Wanchai Maleewong
Publikováno v:
International Journal of Infectious Diseases, Vol 116, Iss , Pp 80-84 (2022)
Background: Opisthorchiasis is caused by an infection with fish-borne liver flukes of the genus Opisthorchis. Opisthorchiasis frequently leads to chronic inflammation in the biliary tract and is classified as a group 1 biological carcinogen by the In
Externí odkaz:
https://doaj.org/article/7418b1a41f7a47b89c3e7c8afdcdb9a7
Autor:
Sujittra Chaiyadet, Sirikachorn Tangkawattana, Michael J Smout, Wannaporn Ittiprasert, Victoria H Mann, Raksawan Deenonpoe, Patpicha Arunsan, Alex Loukas, Paul J Brindley, Thewarach Laha
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010839 (2022)
Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor for cholangiocarcinoma (CCA) in the Mekong Basin countries of Thailand, Lao PDR, Vietnam, Myanmar and Cambodia. Using a novel model of CCA, involving infect
Externí odkaz:
https://doaj.org/article/fdd882f39a254d7a85d1ab254586a92d
Autor:
Fernanda Sales Coelho, Rutchanee Rodpai, André Miller, Shannon E. Karinshak, Victoria H. Mann, Omar dos Santos Carvalho, Roberta Lima Caldeira, Marina de Moraes Mourão, Paul J. Brindley, Wannaporn Ittiprasert
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background Larval development in an intermediate host gastropod snail of the genus Biomphalaria is an obligatory component of the life-cycle of Schistosoma mansoni. Understanding of the mechanism(s) of host defense may hasten the development
Externí odkaz:
https://doaj.org/article/cdff696e0a724bd981a8b278601928ed
Autor:
Patpicha Arunsan, Apisit Chaidee, Christina J. Cochran, Victoria H. Mann, Toshihiko Tanno, Chutima Kumkhaek, Michael J. Smout, Shannon E. Karinshak, Rutchanee Rodpai, Javier Sotillo, Alex Loukas, Thewarach Laha, Paul J. Brindley, Wannaporn Ittiprasert
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 5, Pp 203-216 (2020)
Crosstalk between malignant and neighboring cells contributes to tumor growth. In East Asia, infection with the liver fluke is a major risk factor for cholangiocarcinoma (CCA). The liver fluke Opisthorchis viverrini secretes a growth factor termed li
Externí odkaz:
https://doaj.org/article/3799a2516bc54006934f1b0afa1bd439
Autor:
Benjamin J Hulme, Kathrin K Geyer, Josephine E Forde-Thomas, Gilda Padalino, Dylan W Phillips, Wannaporn Ittiprasert, Shannon E Karinshak, Victoria H Mann, Iain W Chalmers, Paul J Brindley, Cornelis H Hokke, Karl F Hoffmann
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1009828 (2022)
α-galactosidase (α-GAL) and α-N-acetylgalactosaminidase (α-NAGAL) are two glycosyl hydrolases responsible for maintaining cellular homeostasis by regulating glycan substrates on proteins and lipids. Mutations in the human genes encoding either en
Externí odkaz:
https://doaj.org/article/05828ee02d5c4a1e99b9770422f25c16
Autor:
Lakkhana Sadaow, Rutchanee Rodpai, Penchom Janwan, Patcharaporn Boonroumkaew, Oranuch Sanpool, Tongjit Thanchomnang, Hiroshi Yamasaki, Wannaporn Ittiprasert, Victoria H. Mann, Paul J. Brindley, Wanchai Maleewong, Pewpan M. Intapan
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 7, Iss 10, p 308 (2022)
Chronic human liver fluke infections caused by Opisthorchis viverrini and Clonorchis sinensis can last for decades and cause liver and biliary diseases, including life-threatening pathology prior to cholangiocarcinoma (CCA). CCA generally has a poor
Externí odkaz:
https://doaj.org/article/d80b213a7ce249ef89776b0f3d1cb991
Autor:
Michael Smith, Swara Yadav, Olayemi G Fagunloye, Nana Adjoa Pels, Daniel A Horton, Nashwah Alsultan, Andrea Borns, Carolyn Cousin, Freddie Dixon, Victoria H Mann, Clarence Lee, Paul J Brindley, Najib M El-Sayed, Joanna M Bridger, Matty Knight
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009094 (2021)
BackgroundSchistosomiasis remains widespread in many regions despite efforts at its elimination. By examining changes in the transcriptome at the host-pathogen interface in the snail Biomphalaria glabrata and the blood fluke Schistosoma mansoni, we p
Externí odkaz:
https://doaj.org/article/347e2f90ad1d4bc2b77c6bda5239d9af
Autor:
Irina V. Saltykova, Wannaporn Ittiprasert, Kseniya V. Nevskaya, Yulia B. Dorofeeva, Natalia A. Kirillova, Evgeniy S. Kulikov, Vladimir V. Ivanov, Victoria H. Mann, Alexandra G. Pershina, Paul J. Brindley
Publikováno v:
Frontiers in Veterinary Science, Vol 6 (2019)
Aims: There is a general, inverse relationship between helminth infection and allergic diseases including bronchial asthma (BA). Proteins and other mediators released from parasitic worms exert cogent downmodulation of atopic and other allergic react
Externí odkaz:
https://doaj.org/article/f4636eff6388442bb301075158ea9b6b
Autor:
Wannaporn Ittiprasert, Victoria H Mann, Shannon E Karinshak, Avril Coghlan, Gabriel Rinaldi, Geetha Sankaranarayanan, Apisit Chaidee, Toshihiko Tanno, Chutima Kumkhaek, Pannathee Prangtaworn, Margaret M Mentink-Kane, Christina J Cochran, Patrick Driguez, Nancy Holroyd, Alan Tracey, Rutchanee Rodpai, Bart Everts, Cornelis H Hokke, Karl F Hoffmann, Matthew Berriman, Paul J Brindley
Publikováno v:
eLife, Vol 8 (2019)
CRISPR/Cas9-based genome editing has yet to be reported in species of the Platyhelminthes. We tested this approach by targeting omega-1 (ω1) of Schistosoma mansoni as proof of principle. This secreted ribonuclease is crucial for Th2 polarization and
Externí odkaz:
https://doaj.org/article/b44d0fcb161541f696572c51b67e0c12