Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Victoria H John"'
Autor:
Jennifer Hill, Trevor D. Lawley, Christine Hale, Victoria H John, Anton J. Enright, David Goulding, Elena Vigorito, Simon Clare, G. Frankel, Cei Abreu-Goodger, Alan W. Walker, Gordon Dougan, Pietro Mastroeni
Publikováno v:
Infection and Immunity. 81:723-732
MicroRNAs (miRNAs) are small noncoding molecules that control gene expression posttranscriptionally, with microRNA-155 (miR-155) one of the first to be implicated in immune regulation. Here, we show that miR-155-deficient mice are less able to eradic
Publikováno v:
Immunological Reviews. 240:196-210
Salmonella enterica is a genetically broad species harboring isolates that display considerable antigenic heterogeneity and significant differences in virulence potential. Salmonella generally exhibit an invasive potential and they can survive for ex
Autor:
Emma C. Hollands, Derek J. Trezise, Victoria H John, David L. Downie, Mao Xiang Chen, Tim Dale, Leanne Partington, Helen J. Meadows
Publikováno v:
SLAS Discovery. 12:50-60
Planar array electrophysiology techniques were applied to assays for modulators of recombinant hIK and hSK3 Ca2+-activated K+ channels. In CHO-hIK-expressing cells, under asymmetric K+ gradients, small-molecule channel activators evoked time- and vol
Autor:
Caroline Anne Hick, Jeffrey J. Clare, Victoria H John, Derek J. Trezise, Harjeet S Sidhu, Martin J. Main, Andrew J. Powell, Simon Tate, Zoe Gladwell
Publikováno v:
Neuropharmacology. 46(3)
The voltage-gated sodium channel NaV1.8 (SNS, PN3) is thought to be a molecular correlate of the dorsal root ganglion (DRG) tetrodotoxin resistant (TTX-R) Na+ current. TTX-R/NaV1.8 is an attractive therapeutic drug target for inflammatory and neuropa
Autor:
Victoria H. John, Xinmin Xie, Jeffrey J. Clare, Timothy C. Peakman, Heather L. Cater, Timothy J. Dale
Publikováno v:
Pflugers Archiv : European journal of physiology. 441(4)
The human brain voltage-gated Na+ channel type IIA alpha subunit was cloned and stably expressed in Chinese hamster ovary cells and its biophysical and pharmacological properties were studied using whole-cell voltage-clamp. Fast, transient inward cur
Autor:
Victoria H. John
Publikováno v:
Journal of Biomolecular Screening; Feb2007, Vol. 12 Issue 1, p50-60, 11p