Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Victoria H, Brophy"'
Autor:
Wei Yang, Mari Christensen, Jennifer K. Chan, Julie Tsai, Nancy Patten, Ha B. Tran, Grant R. Hillman, Yu Chuan Tai, Patrick Bogard, Claudia M. Litterst, Victoria H. Brophy, Nick Newton, Christopher D. Nelson, Wouter J. Pattje
Publikováno v:
Cancer Research. 82:5156-5156
Non-small cell lung cancer (NSCLC) patients harboring activating mutations in epidermal growth factor receptor (EGFR) are benefited from Tyrosine Kinase Inhibitor (TKI) targeted therapy. However, more than 50% of patients receiving the first or secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1df76bd403e928248f8c31dde0f7c5a
https://doi.org/10.1158/1538-7445.am2022-5156
https://doi.org/10.1158/1538-7445.am2022-5156
Autor:
Rikki M Tanner, Amy I Lynch, Victoria H Brophy, John H Eckfeldt, Barry R Davis, Charles E Ford, Eric Boerwinkle, Donna K Arnett
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23609 (2011)
MMP-9 and -12 function in tissue remodeling and may play roles in cardiovascular disease (CVD). We assessed associations of four MMP polymorphisms and three antihypertensive drugs with cardiovascular outcomes.Hypertensives (n = 42,418) from a double-
Externí odkaz:
https://doaj.org/article/223a86ef0d0742f8af459eee0f8016fc
Autor:
Jing Li, Alan Blair, Harkanwal Halait, Stephanie Gan, Taraneh Rehage, Corey Hoeppner, Victoria H. Brophy, Kyungji Min
Publikováno v:
Archives of pathologylaboratory medicine. 143(2)
Context.— KRAS Mutation Test v2 is used for the qualitative detection and identification of 28 mutations in exons 2, 3, and 4 of the human KRAS gene. Objective.— To verify the performance of KRAS Mutation Test v2 and to evaluate its accuracy by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f85dc847ac96cc5ad994e9de800c40
https://pubmed.ncbi.nlm.nih.gov/30088781
https://pubmed.ncbi.nlm.nih.gov/30088781
Autor:
Erin Richard, Daniel T. O'Connor, Victoria H. Brophy, Lin Liu, Vibha Bhatnagar, Michael S. Lipkowitz, Braj Pandey, Caroline M. Nievergelt
Publikováno v:
American Journal of Hypertension. 25:1188-1194
Blood pressure is a complex quantitative trait with a strong genetic component. In this study, we leveraged the Veterans Affairs electronic medical record system to explore the relationship between Paraoxonase 1 (PON1)-108 C/T (rs705379) and mean art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19327782429e3be33d06f4c4266a2ef
https://doi.org/10.1038/ajh.2012.106
https://doi.org/10.1038/ajh.2012.106
Autor:
Jianli Cao, Victoria H. Brophy, H. Jeffrey Lawrence, Corey Hoeppner, Margot Velez, Sung Sik Lee, Stephen Soviero
Publikováno v:
Virchows Archiv
KRAS mutation testing is mandatory before prescribing anti-epidermal growth factor monoclonal antibodies in the treatment of advanced colorectal cancer. We describe the performance of a TaqMelt polymerase chain reaction (PCR) assay—the cobas® KRAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cdc933fe3b59138d26fab28187272f
https://doi.org/10.1007/s00428-011-1180-0
https://doi.org/10.1007/s00428-011-1180-0
Autor:
Jason Han Lee, Victoria H. Brophy, Lin Liu, Daniel T. O'Connor, Erin Richard, Vibha Bhatnagar, Roland C. Blantz, Christina L. Wassel, Michael S. Lipkowitz, Hossein Aziz
Publikováno v:
American Journal of Hypertension. 24:694-700
BACKGROUND This study focuses on the relationship between β(1)-adrenergic receptor (ADRB1) polymorphisms and blood pressure response to the β-blocker metoprolol among African Americans with early hypertensive nephrosclerosis. METHODS Participants f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d464748a78ed0164558c4cfabe0f5f7c
https://doi.org/10.1038/ajh.2011.39
https://doi.org/10.1038/ajh.2011.39
Publikováno v:
Journal of Clinical Oncology. 36:e24153-e24153
e24153Background: Activating mutations in the mitogen-activated protein kinase pathway are among the most common mutations found in cancer cells. Because of the interaction between BRAF and NRAS, t...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1094a083b6584ea863357b312a54a894
https://doi.org/10.1200/jco.2018.36.15_suppl.e24153
https://doi.org/10.1200/jco.2018.36.15_suppl.e24153
Autor:
Keith C. Norris, Gabriel Contreras, Daniel T. O'Connor, Vibha Bhatnagar, John E. Alcaraz, Victoria H. Brophy, Lawrence J. Appel, Leena Hiremath, Jackson T. Wright, Michael S. Lipkowitz, George L. Bakris, Erin P. Garcia, Erin Richard, John P. Middleton
Publikováno v:
American Journal of Nephrology. 31:95-103
Purpose: To explore the association between CYP3A4 and CYP3A5 gene polymorphisms and blood pressure response to amlodipine among participants from the African-American Study of Kidney Disease and Hypertension Trial randomized to amlodipine (n = 164).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04676f218d0e9b38ed1972442fdd5843
https://doi.org/10.1159/000258688
https://doi.org/10.1159/000258688
Autor:
Hillary H. Hegener, Victoria H. Brophy, Suzanne Cheng, Henry A. Erlich, Paul M. Ridker, Robert Y.L. Zee
Publikováno v:
Stroke. 37:2012-2017
Background and Purpose— In an Icelandic population, gene variants of the phosphodiesterase 4D, cAMP-specific ( PDE4D ) gene were reported to be risk predictors for ischemic stroke. Case–control studies in other populations have yielded mixed evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75db30f1ec51276559c1e806235b5a51
https://doi.org/10.1161/01.str.0000230608.56048.38
https://doi.org/10.1161/01.str.0000230608.56048.38
Autor:
Jianli Cao, Sung Lee, Yiqiao Wu, John F. Palma, Kelli DeMartin, Lilia Corona, Carrie Wong, Jingchuan Li, Stephen Soviero, Victoria H. Brophy, Nitta Lee, Theresa May
Publikováno v:
Journal of Molecular Biomarkers & Diagnosis.
Introduction: Approximately 25% of non-small cell lung cancer (NSCLC) tumors contain mutations in KRAS. These tumors are insensitive to therapy directed against the epidermal growth factor receptor and appear to be resistant to adjuvant chemotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ea07e4481eeb10f669545e4b7fd460
https://doi.org/10.4172/2155-9929.1000246
https://doi.org/10.4172/2155-9929.1000246