Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Victoria Gudiño"'
Autor:
Laura Jiménez-Gracia, Domenica Marchese, Juan C. Nieto, Ginevra Caratù, Elisa Melón-Ardanaz, Victoria Gudiño, Sara Roth, Kellie Wise, Natalie K. Ryan, Kirk B. Jensen, Xavier Hernando-Momblona, Joana P. Bernardes, Florian Tran, Laura Katharina Sievers, Stefan Schreiber, Maarten van den Berge, Tessa Kole, Petra L. van der Velde, Martijn C. Nawijn, Philip Rosenstiel, Eduard Batlle, Lisa M. Butler, Ian A. Parish, Jasmine Plummer, Ivo Gut, Azucena Salas, Holger Heyn, Luciano G. Martelotto
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-36 (2024)
Abstract The use of single-cell technologies for clinical applications requires disconnecting sampling from downstream processing steps. Early sample preservation can further increase robustness and reproducibility by avoiding artifacts introduced du
Externí odkaz:
https://doaj.org/article/d1ab6d70f44f4bfd844fa1f4befa4917
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melón-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M. Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Ingrid Ordás, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Ulcerative colitis and Crohn’s disease are chronic inflammatory intestinal diseases with perplexing heterogeneity in disease manifestation and response to treatment. While the molecular basis for this heterogeneity remains uncharacterized,
Externí odkaz:
https://doaj.org/article/91914e5f5fdd496f894dce921d226bce
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melón-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M. Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Ingrid Ordás, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b3bab41a702941269b02108c15092e84
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Abstract RAC1B is a tumour-related alternative splice isoform of the small GTPase RAC1, found overexpressed in a large number of tumour types. Building evidence suggests it promotes tumour progression but compelling in vivo evidence, demonstrating a
Externí odkaz:
https://doaj.org/article/381b458820c14084a39556c04ee2ac1d
Autor:
Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V. Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E. Hall, Mark Agostino, John Cassidy, Colin Nixon, Alex von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen J. Sansom, Kevin B. Myant
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
RAC1 is a downstream target of the Wnt signaling that promotes intestinal stem cell expansion and tumorigenesis. Here, the authors identify the specific splice variant RAC1B as an important mediator of colorectal tumourigenesis and a potential target
Externí odkaz:
https://doaj.org/article/0d5fa07d90ab4bcca894bd613a859024
Autor:
Jon Peñarando, Laura M. López-Sánchez, Rafael Mena, Silvia Guil-Luna, Francisco Conde, Vanessa Hernández, Marta Toledano, Victoria Gudiño, Michela Raponi, Caroline Billard, Carlos Villar, César Díaz, José Gómez-Barbadillo, Juan De la Haba-Rodríguez, Kevin Myant, Enrique Aranda, Antonio Rodríguez-Ariza
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background Nitric oxide (NO) has been highlighted as an important agent in cancer-related events. Although the inducible nitric oxide synthase (iNOS) isoform has received most attention, recent studies in the literature indicate that the end
Externí odkaz:
https://doaj.org/article/70ca151eb2eb4df98776d11fe02cbc48
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melon-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory intestinal diseases that show a perplexing heterogeneity in manifestations and response to treatment. The molecular basis for this heterogeneity remains uncharacterized. We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd80da16af26ca6d99c6afb1e8d4885
https://doi.org/10.1101/2022.11.28.518139
https://doi.org/10.1101/2022.11.28.518139
Publikováno v:
Expert opinion on investigational drugs. 30(9)
Introduction Ulcerative colitis (UC) is an inflammatory disease of the large intestine. Progress in preclinical therapeutic target discovery and clinical trial design has resulted in the approval of new therapies. Nonetheless, remission rates remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e469a31ffc1e7b20055d835dd6a10f
https://pubmed.ncbi.nlm.nih.gov/34365869
https://pubmed.ncbi.nlm.nih.gov/34365869
Autor:
George Dickson, Linda Popplewell, Farhat V N Din, Adam E. Hall, Kevin Myant, Malcolm G. Dunlop, Paz Freile, Alfonso Bolado, Caroline V. Billard, Victoria Gudiño, Stuart Aitken, Mark Agostino, David A. Stevenson, Douglas Strathdee, Laura Murphy, Owen J. Sansom, Alex von Kriegsheim, Sebastian Öther-Gee Pohl, John W. Cassidy, Patrizia Cammareri, Colin Nixon, Ann P. Wheeler
Publikováno v:
Nature Communications
Gudiño, V, Öther-Gee Pohl, S, V Billard, C, Cammareri, P, Bolado Carrancio, A, Aitken, S, Stevenson, D, Hall, A, Agostino, M, Cassidy, J, Nixon, C, von Kriegsheim, A, Friele, P, Popplewell, L, Dickson, G, Murphy, L, Wheeler, A P, Dunlop, M G, Din, F V N, Strathdee, D, J. Sansom, O & Myant, K B 2021, ' Rac1b modulates intestinal tumourigenesis via modulation of Wnt and Egfr signalling pathways ', Nature Communications . https://doi.org/10.1038/s41467-021-22531-3
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Gudiño, V, Öther-Gee Pohl, S, V Billard, C, Cammareri, P, Bolado Carrancio, A, Aitken, S, Stevenson, D, Hall, A, Agostino, M, Cassidy, J, Nixon, C, von Kriegsheim, A, Friele, P, Popplewell, L, Dickson, G, Murphy, L, Wheeler, A P, Dunlop, M G, Din, F V N, Strathdee, D, J. Sansom, O & Myant, K B 2021, ' Rac1b modulates intestinal tumourigenesis via modulation of Wnt and Egfr signalling pathways ', Nature Communications . https://doi.org/10.1038/s41467-021-22531-3
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Current therapeutic options for treating colorectal cancer have little clinical efficacy and acquired resistance during treatment is common, even following patient stratification. Understanding the mechanisms that promote therapy resistance may lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d761f8e664c9c0e74b157a8fb7baff43
https://eprints.gla.ac.uk/239120/1/239120.pdf
https://eprints.gla.ac.uk/239120/1/239120.pdf
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death & Disease
RAC1B is a tumour-related alternative splice isoform of the small GTPase RAC1, found overexpressed in a large number of tumour types. Building evidence suggests it promotes tumour progression but compelling in vivo evidence, demonstrating a role in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfed49a5cd8d1761901c1bbc5ecba9c7