Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Victoria G. Pederick"'
Autor:
Stephanie L. Neville, Bliss A. Cunningham, Eve A. Maunders, Aimee Tan, Jacinta A. Watts, Katherine Ganio, Bart A. Eijkelkamp, Victoria G. Pederick, Raquel Gonzalez de Vega, David Clases, Philip A. Doble, Christopher A. McDevitt
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Metal ions are required by all organisms for the chemical processes that support life. However, in excess they can also exert toxicity within biological systems. During infection, bacterial pathogens such as Streptococcus pneumoniae are expo
Externí odkaz:
https://doaj.org/article/ff64c4c380604a1ead62e2b26420412f
Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae
Autor:
Marina L. Župan, Zhenyao Luo, Katherine Ganio, Victoria G. Pederick, Stephanie L. Neville, Evelyne Deplazes, Boštjan Kobe, Christopher A. McDevitt
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Streptococcus pneumoniae scavenges essential zinc ions from the host during colonization and infection. This is achieved by the ATP-binding cassette transporter, AdcCB, and two solute-binding proteins (SBPs), AdcA and AdcAII. It has been established
Externí odkaz:
https://doaj.org/article/429def92a3784928b8961d7b9ecdb77f
Autor:
Zhenyao Luo, Jacqueline R. Morey, Evelyne Deplazes, Alina Motygullina, Aimee Tan, Katherine Ganio, Stephanie L. Neville, Nikolaos Eleftheriadis, Michael Isselstein, Victoria G. Pederick, James C. Paton, Thorben Cordes, Jeffrey R. Harmer, Bostjan Kobe, Christopher A. McDevitt
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Zinc is an essential nutrient for the virulence of bacterial pathogens such as Streptococcus pneumoniae
Externí odkaz:
https://doaj.org/article/328f9ad9683d40209de57bbc91164209
Autor:
Bart A Eijkelkamp, Jacqueline R Morey, Stephanie L Neville, Aimee Tan, Victoria G Pederick, Nerida Cole, Prashina P Singh, Cheryl-Lynn Y Ong, Raquel Gonzalez de Vega, David Clases, Bliss A Cunningham, Catherine E Hughes, Iain Comerford, Erin B Brazel, Jonathan J Whittall, Charles D Plumptre, Shaun R McColl, James C Paton, Alastair G McEwan, Philip A Doble, Christopher A McDevitt
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007957 (2019)
Human zinc deficiency increases susceptibility to bacterial infection. Although zinc supplementation therapies can reduce the impact of disease, the molecular basis for protection remains unclear. Streptococcus pneumoniae is a major cause of bacteria
Externí odkaz:
https://doaj.org/article/c91b75b319b54f9b8df07364e06cec17
Autor:
Jhih-Hang Jiang, Karl A. Hassan, Stephanie L. Begg, Thusitha W. T. Rupasinghe, Varsha Naidu, Victoria G. Pederick, Marjan Khorvash, Jonathan J. Whittall, James C. Paton, Ian T. Paulsen, Christopher A. McDevitt, Anton Y. Peleg, Bart A. Eijkelkamp
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Free fatty acids hold important immune-modulatory roles during infection. However, the host’s long-chain polyunsaturated fatty acids, not commonly found in the membranes of bacterial pathogens, also have significant broad-spectrum antibact
Externí odkaz:
https://doaj.org/article/9d970be129be462eb8daae5917e68e67
Autor:
Bart A. Eijkelkamp, Stephanie L. Begg, Victoria G. Pederick, Claudia Trapetti, Melissa K. Gregory, Jonathan J. Whittall, James C. Paton, Christopher A. McDevitt
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Free fatty acids hold dual roles during infection, serving to modulate the host immune response while also functioning directly as antimicrobials. Of particular importance are the long chain polyunsaturated fatty acids, which are not commonly found i
Externí odkaz:
https://doaj.org/article/4d5e76a96e3141798e1c7133a02eb24f
Autor:
Jacqueline R. Morey, Michael Isselstein, Thorben Cordes, Christopher A. McDevitt, Jeffrey Harmer, James C. Paton, Stephanie L. Neville, Katherine Ganio, Evelyne Deplazes, Alina E. Motygullina, Bostjan Kobe, Victoria G. Pederick, Nikolaos Eleftheriadis, Zhenyao Luo, Aimee Tan
Publikováno v:
mBio
mBio, Vol 12, Iss 1 (2021)
Mbio, 12(1):e01958-20, 1-14. AMER SOC MICROBIOLOGY
mBio, Vol 12, Iss 1 (2021)
Mbio, 12(1):e01958-20, 1-14. AMER SOC MICROBIOLOGY
Zinc is an essential nutrient for the virulence of bacterial pathogens such as Streptococcus pneumoniae. Many Gram-positive bacteria use a two-domain lipoprotein for zinc acquisition, but how this class of metal-recruiting proteins acquire zinc and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f683506418114fb0f5f4dc94ce2e904e
https://doi.org/10.1128/mBio.01958-20
https://doi.org/10.1128/mBio.01958-20
Autor:
Karl A. Hassan, James C. Paton, Bart A. Eijkelkamp, Victoria G. Pederick, Varsha Naidu, Amy K. Cain, Felise G. Adams, Saleh F. Alquethamy, Marjan Khorvash, Ian T. Paulsen, Maoge Zang, Christopher A. McDevitt
Publikováno v:
ACS Infectious Diseases. 6:150-158
Acinetobacter baumannii is a ubiquitous Gram-negative bacterium, that is associated with significant disease in immunocompromised individuals. The success of A. baumannii is partly attributable to its high level of antibiotic resistance. Further, A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db4d3300ea661cc721069642e9240e9
https://doi.org/10.1021/acsinfecdis.9b00351
https://doi.org/10.1021/acsinfecdis.9b00351
Autor:
Christopher A. McDevitt, Zonghan Xie, Mohammad Sharear Kabir, Hu Zhang, Zhifeng Zhou, Paul Munroe, Song Xu, Victoria G. Pederick, Afshin Karami
Publikováno v:
Surface Engineering. 35:596-603
Cr–Ag coatings for antimicrobial surface applications were fabricated by magnetron sputtering. The coating microstructure and mechanical properties were characterised using XPS, XRD, FESEM, TEM and...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::192e319055a239c3acb76c4103e3ec7c
https://doi.org/10.1080/02670844.2018.1537082
https://doi.org/10.1080/02670844.2018.1537082
Publikováno v:
FEBS Letters. 592:2341-2350
The bacterium Streptococcus pneumoniae (the pneumococcus) is a major human pathogen that requires Zn2+ for its survival and virulence in the host environment. Polyhistidine triad protein D (PhtD) has a known role in pneumococcal Zn2+ homeostasis. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c624fdd1a50ea2374284e3784adf2711
https://doi.org/10.1002/1873-3468.13122
https://doi.org/10.1002/1873-3468.13122