Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Victoria Gómez-Abellán"'
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Akademický článek
Deciphering the Role and Signaling Pathways of PKCα in Luminal A Breast Cancer Cells
Autor: Emilio M. Serrano-López, Teresa Coronado-Parra, Consuelo Marín-Vicente, Zoltan Szallasi, Victoria Gómez-Abellán, María José López-Andreo, Marcos Gragera, Juan C. Gómez-Fernández, Rubén López-Nicolás, Senena Corbalán-García
Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 22, p 14023 (2022)
Protein kinase C (PKC) comprises a family of highly related serine/threonine protein kinases involved in multiple signaling pathways, which control cell proliferation, survival, and differentiation. The role of PKCα in cancer has been studied for ma
Externí odkaz: https://doaj.org/article/15c72ba2bbc944ce927569469619fa53
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2
Akademický článek
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
Autor: Sylwia D. Tyrkalska, Sergio Candel, Diego Angosto, Victoria Gómez-Abellán, Fátima Martín-Sánchez, Diana García-Moreno, Rubén Zapata-Pérez, Álvaro Sánchez-Ferrer, María P. Sepulcre, Pablo Pelegrín, Victoriano Mulero
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
The role of guanylate-binding proteins (GBPs) in innate immunity is increasingly recognized. Here the authors show that GBP4 activates inflammasome in zebrafish neutrophils, and that this process is critical for the clearance of Salmonellainfection v
Externí odkaz: https://doaj.org/article/55bfda7fda31404dab8fdb2f0bb50c7f
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3
Peroxisome proliferator-activated receptors alpha and beta mediate the anti-inflammatory effects of the cyclopentenone prostaglandin 15-deoxy-Δ12,14-PGJ2 in fish granulocytes
Autor: Victoria Gómez-Abellán, Ana B. Pérez-Oliva, Isabel Cabas, Fatma Hermi, Marta Arizcun, Diana García-Moreno, María P. Sepulcre, Victoriano Mulero
Publikováno v: e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
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Prostaglandins (PGs) are highly reactive small lipophilic molecules derived from polyunsaturated fatty acids of the cell membrane and play a key role in the resolution of inflammation processes. 15-deoxy-Δ12,14-PGJ2 (15dPGJ2) is a cyclopentenone PG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67a9785312d4e571bfe6373dd77ea1a
https://hdl.handle.net/10508/15905
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4
Peroxisome proliferator-activated receptors alpha and beta mediate the anti-inflammatory effects of the cyclopentenone prostaglandin 15-deoxy-Δ
Autor: Victoria, Gómez-Abellán, Ana B, Pérez-Oliva, Isabel, Cabas, Fatma, Hermi, Marta, Arizcun, Diana, García-Moreno, María P, Sepulcre, Victoriano, Mulero
Publikováno v: Developmental and comparative immunology. 136
Prostaglandins (PGs) are highly reactive small lipophilic molecules derived from polyunsaturated fatty acids of the cell membrane and play a key role in the resolution of inflammation processes. 15-deoxy-Δ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9320c3ab3ddb951216248ea26f5eca31
https://pubmed.ncbi.nlm.nih.gov/35948178
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5
The molecular, functional and phylogenetic characterization of PGE2 receptors reveals their different roles in the immune response of the teleost fish gilthead seabream (Sparus aurata L.)
Autor: Elena Sarropoulou, Marta Arizcun, Azucena López-Muñoz, Victoria Gómez-Abellán, Diana García-Moreno, María P. Sepulcre, Oueslati Ridha, Fatma Hermi, Victoriano Mulero, Ana B. Pérez-Oliva
Publikováno v: e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
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Prostaglandin E2 (PGE2) plays an important role in immune activities in teleost fish, including seabream. However, receptors involved in PGE2 signaling, as well as the pathways activated downstream, are largely unknown. In this study, one ortholog of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77427bc6d9b714cddd45ffca2a5a6494
https://hdl.handle.net/10508/11772
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7
The role of prostaglandins in the regulation of fish immunity
Autor: Victoria Gómez-Abellán, María P. Sepulcre
Publikováno v: Molecular Immunology. 69:139-145
Prostaglandins (PGs) play a key role in the development of the immune response. These molecules are produced by a variety of cells including leukocytes, macrophages being the most important source of PGs for the innate immune system. PGs can elicit a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7117ae4d0a2a6063f4b0921766928290
https://doi.org/10.1016/j.molimm.2015.09.022
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8
Identification of an interferon-stimulated gene, isg15, involved in host immune defense against viral infections in gilthead seabream (Sparus aurata L.)
Autor: Marta Arizcun, Victoria Gómez-Abellán, Julia Béjar, María P. Sepulcre, Esther García-Rosado, Daniel Álvarez-Torres
Publikováno v: e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
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Interferons (IFNs) play a key role in the innate immunity of vertebrates against viral infections by inducing hundreds of IFN-stimulated genes (ISGs), such as isg15. Isg15 is an ubiquitin-like protein, which can conjugate cellular and viral proteins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fff31cdaed55ae311137d7710adec7a
https://hdl.handle.net/10508/11782
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9
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins
Autor: Pablo Pelegrín, Diego Angosto, Fátima Martín-Sánchez, Sergio Candel, Álvaro Sánchez-Ferrer, Rubén Zapata-Pérez, Sylwia D. Tyrkalska, Victoriano Mulero, Diana García-Moreno, Victoria Gómez-Abellán, María P. Sepulcre
Publikováno v: Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Digital.CSIC. Repositorio Institucional del CSIC
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17 páginas, 10 figuras.-- Sylwia Tyrkalska ... et al.-- This work is licensed under a Creative Commons Attribution 4.0 International License
Inflammasomes are cytosolic molecular platforms that alert the immune system about the presence of infe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313bb055b7a660d0750da8d76e422861
http://europepmc.org/articles/PMC4932187
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10
Prostaglandin E2 promotes M2 polarization of macrophages via a cAMP/CREB signaling pathway and deactivates granulocytes in teleost fish
Autor: Victoriano Mulero, Victoria Gómez-Abellán, Marta Arizcun, María P. Sepulcre, Jana Montero
Publikováno v: e-IEO: Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
Instituto Español de Oceanografía
e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
instname
The profile of prostaglandin (PG) production is determined by the differential expression of the enzymes involved in their production and degradation. Although the production of PGE2 by fish leukocytes has been relatively well studied in several fish
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7e29600772fb6e3620f7d9475a9018
https://hdl.handle.net/10508/10349
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