Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Victoria Fairweather"'
Publikováno v:
Pneumo News. 12:38-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e69f78eacb1299743428062f6eb480
https://doi.org/10.1007/s15033-020-1836-z
https://doi.org/10.1007/s15033-020-1836-z
Publikováno v:
Allergy 75, 2352-2354 (2020)
Our climate is changing at an unprecedented rate. This not only has impacts on the planet and the ecosystem, with extinction rates rising rapidly, but also on human health (Figure 1). The effects of climate change are and will continue to disrupt the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a891c4811b284979702ea1e9ccf70367
https://pubmed.ncbi.nlm.nih.gov/32779793
https://pubmed.ncbi.nlm.nih.gov/32779793
Autor:
Jan Frayne, Marieangela C. Wilson, Winnie W. Y. Lau, R. Leo Brady, Ben M. Richardson, Nicholas M. Burton, David J. Anstee, Belinda K. Singleton, Victoria Fairweather, Steve F. Parsons, Kongtana Trakarnsanga
Publikováno v:
Blood. 118:3137-3145
Mutations in the human erythroid Krüppel-like factor (EKLF) can lead to either anemia or the benign InLu phenotype. To elucidate the relationship between these mutations and the differing phenotypes, we prepared recombinant forms of wild-type and 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721d555261ad062caa2df772ce2abb86
https://doi.org/10.1182/blood-2011-04-349985
https://doi.org/10.1182/blood-2011-04-349985
Autor:
Karen Campos-León, R. Leo Brady, Victoria Fairweather, Madeleine Strickland, Christopher Williams, Matthew P. Crump, Kevin Gaston, Craig Brown
Publikováno v:
Brown, C A, Campos Leon, K, Strickland, M, Williams, C, Fairweather, V S S, Brady, R L, Crump, M P & Gaston, K 2011, ' Protein flexibility directs DNA recognition by the papillomavirus E2 proteins ', Nucleic Acids Research, vol. 39, no. 7, pp. 2969-2980 . https://doi.org/10.1093/nar/gkq1217
Nucleic Acids Research
Nucleic Acids Research
Although DNA flexibility is known to play an important role in DNA–protein interactions, the importance of protein flexibility is less well understood. Here, we show that protein dynamics are important in DNA recognition using the well-characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e472aa542731a90354350f5854e3e6
https://doi.org/10.1093/nar/gkq1217
https://doi.org/10.1093/nar/gkq1217
Publikováno v:
FEMS microbiology letters. 362(3)
IHF is a protein of the bacterial nucleoid proteins (NAPs for nucleoid-associated proteins) involved in DNA structuring and transcription regulation. In vivo interplay between different NAPs determines selectively the expression rate of many genes. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33421c7df2c190d85536bf3d7a5704e5
https://pubmed.ncbi.nlm.nih.gov/25673659
https://pubmed.ncbi.nlm.nih.gov/25673659
Publikováno v:
Nucleic Acids Research
The E2 proteins are transcription/replication factors from papillomaviruses. Human papillomaviruses (HPVs) can be broadly divided in two groups; low-risk HPV subtypes cause benign warts while high-risk HPVs give rise to cervical cancer. Although a ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cae2032951de7fe63305c3bf284c11
https://pubmed.ncbi.nlm.nih.gov/16914454
https://pubmed.ncbi.nlm.nih.gov/16914454
Autor:
Victoria Fairweather, R. Leo Brady, Tim Joseph-Horne, Rebecca Conners, Apirat Chaikuad, Dilek Turgut-Balik
Publikováno v:
Biochemistry. 44(49)
Malaria caused by Plasmodium vivax is a major cause of global morbidity and, in rare cases, mortality. Lactate dehydrogenase is an essential Plasmodium protein and, therefore, a potential antimalarial drug target. Ideally, drugs directed against this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262ad36e93c81a56b32bc890dccd90a9
https://pubmed.ncbi.nlm.nih.gov/16331982
https://pubmed.ncbi.nlm.nih.gov/16331982
Autor:
Jan Frayne, D J Anstee, S.F. Parsons, Belinda K. Singleton, R. Leo Brady, Victoria Fairweather, Winnie W. Y. Lau, Nicholas M. Burton
Publikováno v:
Blood. 114:162-162
Abstract 162 We describe a single-point mutation in the transcription factor EKLF associated with dyserythropoietic anemia. The female Danish patient was extensively studied in the early 1990's (Wickramasinghe et al. Br J Haem 1991,79:322; Tang et al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d936eafa50bc905e471eff437dc94ff
https://doi.org/10.1182/blood.v114.22.162.162
https://doi.org/10.1182/blood.v114.22.162.162