Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Victoria E. Wang"'
Autor:
Victoria E. Wang, Anatoly Urisman, Lee Albacker, Siraj Ali, Vincent Miller, Rahul Aggarwal, David Jablons
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-4 (2017)
Abstract Background Large cell neuroendocrine tumor (LCNEC) of the lung is a rare and aggressive tumor similar to small cell lung cancer (SCLC). Thus, it is often treated similarly to SCLC in the front-line setting with a platinum doublet. However, t
Externí odkaz:
https://doaj.org/article/7b4f6047582f438b9deff80b0558382a
Autor:
Charalambos Andreadis, Frank McCormick, Gabriela K. Fragiadakis, Pamela N. Munster, David P. Carbone, Chun J. Ye, Vivian Weinberg, Michael Flanders, Emma McMahon, Karin M. Gaensler, Peter H. Sayre, Thomas G. Martin, Lloyd E. Damon, Rebecca Olin, Gabriel N. Mannis, Matthew Settles, Aaron C. Logan, Tommy Jiang, Blythe Durbin-Johnson, Arjun A. Rao, Gregory K. Behbehani, Ravi K. Patel, Bradley W. Blaser, Victoria E. Wang
Supplementary Data from Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9274c477d2ab2f5535764c6f7ffb71
https://doi.org/10.1158/2643-3230.22543692
https://doi.org/10.1158/2643-3230.22543692
Autor:
Charalambos Andreadis, Frank McCormick, Gabriela K. Fragiadakis, Pamela N. Munster, David P. Carbone, Chun J. Ye, Vivian Weinberg, Michael Flanders, Emma McMahon, Karin M. Gaensler, Peter H. Sayre, Thomas G. Martin, Lloyd E. Damon, Rebecca Olin, Gabriel N. Mannis, Matthew Settles, Aaron C. Logan, Tommy Jiang, Blythe Durbin-Johnson, Arjun A. Rao, Gregory K. Behbehani, Ravi K. Patel, Bradley W. Blaser, Victoria E. Wang
Acute myeloid leukemia (AML) patients refractory to induction therapy or relapsed within 1 year have poor outcomes. Autocrine production of hepatocyte growth factor by myeloid blasts drives leukemogenesis in preclinical models. A phase Ib trial evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6723e49382eda7eadaaae9301736b6
https://doi.org/10.1158/2643-3230.c.6550365.v1
https://doi.org/10.1158/2643-3230.c.6550365.v1
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Table S4 shows the moleculared used in the pharmacological screen and the corresponding IC50 values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622973da518a4e95c46be3cdd78232ff
https://doi.org/10.1158/1078-0432.22471104.v1
https://doi.org/10.1158/1078-0432.22471104.v1
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ab929e7fad138154e67d8bf875c65f
https://doi.org/10.1158/1078-0432.22471098.v1
https://doi.org/10.1158/1078-0432.22471098.v1
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Table S5 shows the raw counts from RNA sequencing of paired non-small cell lung cancer samples with BRAF mutations pre- and post-treatment using BRAF/MEK inhibitor combinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bfeb5d81d195b47cb408b54e48614a
https://doi.org/10.1158/1078-0432.22471101
https://doi.org/10.1158/1078-0432.22471101
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Figure S1 shows the A375 VCR cells being resistant and addicted to dabrafenib and trametinib (A,B), that knockdown of STAT3 had no effect on drug resistance (C,D), Caspase-Glo assays of drug-treated cells (F), and time course of pFGFR1 and pERK of dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10584150a393afa9b5a8b032bd0aea74
https://doi.org/10.1158/1078-0432.22471119.v1
https://doi.org/10.1158/1078-0432.22471119.v1
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Table S3 shows unique mutations in A375 VCR cells compared to parental using exome sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ad20d24fd4132595926ef58475c7a4
https://doi.org/10.1158/1078-0432.22471110.v1
https://doi.org/10.1158/1078-0432.22471110.v1
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Purpose:Combined MAPK pathway inhibition using dual BRAF and MEK inhibitors has prolonged the duration of clinical response in patients with BRAFV600E-driven tumors compared with either agent alone. However, resistance frequently arises.Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b965b87b542b9b06b1a70331b020566
https://doi.org/10.1158/1078-0432.c.6527784
https://doi.org/10.1158/1078-0432.c.6527784
Autor:
Frank McCormick, Jeff Settleman, Piro Lito, Rene Bernards, Keith T. Flaherty, David P. Carbone, Anatoly Urisman, Catherine Wilson, Eva Lin, Yi Cao, Dennie T. Frederick, Jenny Y. Xue, Victoria E. Wang
Table S1 shows mutations in A375 VemR cells compared to the parental using exome sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f55881816f5b7d6d224ba0221665f5
https://doi.org/10.1158/1078-0432.22471116.v1
https://doi.org/10.1158/1078-0432.22471116.v1