Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Victoria E. Sepúlveda"'
Autor:
Victoria E. Sepúlveda, Jonathan A. Rader, Jingbaoyi (Janet) Li, William E. Goldman, Daniel R. Matute
Publikováno v:
mSphere, Vol 9, Iss 6 (2024)
ABSTRACT Histoplasmosis is an endemic mycosis that often presents as a respiratory infection in immunocompromised patients. Hundreds of thousands of new infections are reported annually around the world. The etiological agent of the disease, Histopla
Externí odkaz:
https://doaj.org/article/ff1a622c23fb4c2d8c7c16701e6a5bb8
Autor:
Heidi Mavengere, Kathleen Mattox, Marcus M. Teixeira, Victoria E. Sepúlveda, Oscar M. Gomez, Orville Hernandez, Juan McEwen, Daniel R. Matute
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT The fungus Paracoccidioides is a prevalent human pathogen endemic to South America. The genus is composed of five species. In this report, we use 37 whole-genome sequences to study the allocation of genetic variation in Paracoccidioides. We
Externí odkaz:
https://doaj.org/article/4e2c0e9e476d43c3884e4a66dca15383
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Klebsiella pneumoniae has a remarkable ability to cause a wide range of human diseases. It is divided into two broad classes: classical strains that are a notable problem in health care settings due to multidrug resistance, and hypervirulent
Externí odkaz:
https://doaj.org/article/209942c105344f6e8186e47308c3054c
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Histoplasma is an endemic dimorphic fungus that can cause disease in healthy and immunocompromised individuals after the transition of inhaled spores into the facultative intracellular yeast form. There is substantial diversity among Histopl
Externí odkaz:
https://doaj.org/article/1b19787a64a34ab884782b248f5acaaa
Autor:
Kara R. Eichelberger, Victoria E. Sepúlveda, John Ford, Sara R. Selitsky, Piotr A. Mieczkowski, Joel S. Parker, William E. Goldman
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Following inhalation, Yersinia pestis rapidly colonizes the lung to establish infection during primary pneumonic plague. Although several adhesins have been identified in Yersinia spp., the factors mediating early Y. pestis adherence in the
Externí odkaz:
https://doaj.org/article/ab34213a353c47eab54d84d386739c36
Autor:
Kimberly A. Walker, Taryn A. Miner, Michelle Palacios, Dominika Trzilova, Daniel R. Frederick, Christopher A. Broberg, Victoria E. Sepúlveda, Joshua D. Quinn, Virginia L. Miller
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidru
Externí odkaz:
https://doaj.org/article/d253aa4c055244b39986388f75d67fdc
Autor:
Victoria E. Sepúlveda, Roberto Márquez, David A. Turissini, William E. Goldman, Daniel R. Matute
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Histoplasma capsulatum is a pathogenic fungus that causes life-threatening lung infections. About 500,000 people are exposed to H. capsulatum each year in the United States, and over 60% of the U.S. population has been exposed to the fungus
Externí odkaz:
https://doaj.org/article/afe36cd2a33d44298b0c23a6f64b15a8
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Infection with the dimorphic fungus Histoplasma capsulatum results from the inhalation of contaminated soil. Disease outcome is variable and depends on the immune status of the host, number of organisms inhaled, and the H. capsulatum strain.
Externí odkaz:
https://doaj.org/article/f1acf659967741a5bc973a1423ceec06
Autor:
Emily N. Kennedy, Robert B. Bourret, William E. Goldman, Clay A. Foster, Victoria E. Sepúlveda
Publikováno v:
Trends Microbiol
Bacterial two-component regulatory systems (TCSs) mediate signal transduction by transferring phosphoryl groups between sensor kinase and response regulator proteins, sometimes using intermediary histidine-phosphotransferase (Hpt) domains to form mul
Publikováno v:
mSphere
Acute pulmonary histoplasmosis in healthy individuals comprises most of the disease burden caused by the fungal pathogen Histoplasma. Fungal pneumonia is frequently delayed in diagnosis and treatment due to a prolonged period of quiescence early duri