Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Victoria E. Palau"'
Autor:
Brian M. Cartwright, Jaclyn N. Corso, Janet Lightner, Crystal Whitted, Ruben D. Torrenegra, Koyamangalath Krishnan, Victoria E. Palau
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115546- (2023)
Surgically unresectable colorectal and pancreatic carcinomas have a high rate of mortality as current therapeutic options are limited. One common chemotherapeutic used to broadly treat both cancers is 5-flurouracil (5-Fu); however, treatment serves o
Externí odkaz:
https://doaj.org/article/67b42ad599f3426bb61a9ccc2870114e
Autor:
Christine Moore, Victoria E. Palau, Rashid Mahboob, Janet Lightner, William Stone, Koyamangalath Krishnan
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background α-tocopherol (AT) and γ-tocotrienol (GT3) are vitamin E isoforms considered to have potential chemopreventive properties. AT has been widely studied in vitro and in clinical trials with mixed results. The latest clinical study (
Externí odkaz:
https://doaj.org/article/e2ccc89cb6144ce2b0a56d2f501ff1cb
Autor:
Victoria E. Palau, Kanishka Chakraborty, Daniel Wann, Janet Lightner, Keely Hilton, Marianne Brannon, William Stone, Koyamangalath Krishnan
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background Ceramide synthesis and metabolism is a promising target in cancer drug development. γ-tocotrienol (GT3), a member of the vitamin E family, orchestrates multiple effects that ensure the induction of apoptosis in both, wild-type an
Externí odkaz:
https://doaj.org/article/f749ecf3434342d09fbb621de6daecbe
Autor:
Joel K. Annor-Gyamfi, John M. Jarrett, Joseph O. Osazee, Dobrusia Bialonska, Crystal Whitted, Victoria E. Palau, Abbas G. Shilabin
Publikováno v:
Heliyon, Vol 4, Iss 2 (2018)
Cancer remains the second major cause of death in the world. Thus, there is a pressing need to identify potential synthetic route for the development of novel anticancer agents which will serve as lead compounds to effectively combat this life-threat
Externí odkaz:
https://doaj.org/article/e06166388e24400d86403813841495c4
Autor:
Samson N. Dada, Godwin K. Babanyinah, Michael T. Tetteh, Victoria E. Palau, Zachary F. Walls, Koyamangalath Krishnan, Zacary Croft, Assad U. Khan, Guoliang Liu, Thomas E. Wiese, Ellen Glotser, Hua Mei
Publikováno v:
ACS omega. 7(27)
With special properties such as excellent fluoresce features, low toxicity, good biocompatibility, permeability, and easy clearance from the body, carbon dot (CD)-based nanoparticles (NPs) have the potential to deliver drugs and use in vivo diagnosti
Autor:
Mailien, Rogers, Sumit, Kalra, Julia, Moukharskaya, Kanishka, Chakraborty, Maximilian, Niyazi, Koyamangalath, Krishnan, Janet, Lightner, Marianne, Brannon, William L, Stone, Victoria E, Palau
Publikováno v:
Anticancer research. 35(4)
The mevalonate pathway plays an important role in cancer biology and has been targeted with farnesyl transferase inhibitors, although their efficacy is limited due to significant adverse effects. Statins and bisphosphonates inhibit the mevalonate pat
Autor:
Timothy M LeJeune, Hei Yin Tsui, Laura B Parsons, Gerald E Miller, Crystal Whitted, Kayla E Lynch, Robert E Ramsauer, Jasmine U Patel, Jarrett E Wyatt, Doris S Street, Carolyn B Adams, Brian McPherson, Hei Man Tsui, Julie A Evans, Christopher Livesay, Ruben D Torrenegra, Victoria E Palau
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142928 (2015)
Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals
Externí odkaz:
https://doaj.org/article/ff2eb67b98f4422ea6b50621b8452d8f
Exacerbation of celecoxib-induced renal injury by concomitant administration of misoprostol in rats.
Autor:
Dustin L Cooper, Derek E Murrell, Christopher M Conder, Victoria E Palau, Grace E Campbell, Shaun P Lynch, James W Denham, Angela V Hanley, Kenny W Bullins, Peter C Panus, Krishna Singh, Sam Harirforoosh
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89087 (2014)
Nonsteroidal anti-inflammatory drugs (NSAIDs) can produce adverse effects by inhibiting prostaglandin (PG) synthesis. A PGE1 analogue, misoprostol, is often utilized to alleviate NSAID-related gastrointestinal side effects. This study examined the ef
Externí odkaz:
https://doaj.org/article/e877bbf4891f4ae0bbc314cca3e84ab9