Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Victoria E. Ahn"'
Publikováno v:
Protein Science. 15:1849-1857
Saposins A and C are sphingolipid activator proteins required for the lysosomal breakdown of galactosylceramide and glucosylceramide, respectively. The saposins interact with lipids, leading to an enhanced accessibility of the lipid headgroups to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153d9b113993658d48e3ff287cf49519
https://doi.org/10.1110/ps.062256606
https://doi.org/10.1110/ps.062256606
SummaryLDL receptor-related proteins 5 and 6 (LRP5/6) are coreceptors for Wnt growth factors, and also bind Dkk proteins, secreted inhibitors of Wnt signaling. The LRP5/6 ectodomain contains four β-propeller/EGF-like domain repeats. The first two re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a4d3394db71c4019c48785f4183ad5
https://europepmc.org/articles/PMC3215855/
https://europepmc.org/articles/PMC3215855/
Autor:
Nenad Tomasevic, Victoria E. Ahn, Minke E. Binnerts, Jason Williams, William I. Weis, Kyung Ah Kim, Shirlee Yonkovich, Wouter Korver, Jessica M. Bright, Mei Zhou, John Leung, Shouchun Liu, Melissa Dixon, Delphine Gros, Xiaoming Zhan, Arie Abo
Publikováno v:
Molecular biology of the cell. 20(15)
The Wnt coreceptor LRP6 is required for canonical Wnt signaling. To understand the molecular regulation of LRP6 function, we generated a series of monoclonal antibodies against the extra cellular domain (ECD) of LRP6 and selected a high-affinity mAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23f8d6f53efe68392392cfb77b96fda
https://pubmed.ncbi.nlm.nih.gov/19477926
https://pubmed.ncbi.nlm.nih.gov/19477926
Autor:
Gilbert G. Privé, Eileen I. Lo, Peter M. Hwang, Russell E. Bishop, Lewis E. Kay, Victoria E. Ahn, Christian K Engel, Lu Chen
The ability of enzymes to distinguish between fatty acyl groups can involve molecular measuring devices termed hydrocarbon rulers, but the molecular basis for acyl-chain recognition in any membrane-bound enzyme remains to be defined. PagP is an outer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a525c67a98c5fddae85cc6c931f2e9
https://europepmc.org/articles/PMC514935/
https://europepmc.org/articles/PMC514935/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 100(1)
Saposin B is a small, nonenzymatic glycosphingolipid activator protein required for the breakdown of cerebroside sulfates (sulfatides) within the lysosome. The protein can extract target lipids from membranes, forming soluble protein-lipid complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621144f8351a35b8f84cb6930d93e3d8
https://pubmed.ncbi.nlm.nih.gov/12518053
https://pubmed.ncbi.nlm.nih.gov/12518053
Autor:
Jason Higginson, Gilbert G. Privé, Victoria E. Ahn, Arvan L. Fluharty, Kym F. Faull, Julian P. Whitelegge
Publikováno v:
Protein expression and purification. 27(1)
Saposin B (also known as cerebroside sulfate activator or CSAct) is a small non-enzymatic glycoprotein required for the breakdown of cerebroside sulfates (sulfatides) in lysosomes. Saposin B contains three intramolecular disulfide bridges, exists as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0797ec2ef29fb2a724a8ff3de176fe6
https://pubmed.ncbi.nlm.nih.gov/12510003
https://pubmed.ncbi.nlm.nih.gov/12510003
Autor:
William I. Weis, Roel Nusse, Matthew Ling-Hon Chu, Danette L. Daniels, Victoria E. Ahn, Hee Jung Choi
Publikováno v:
Structure. (7):1235-1242
SummaryWnts are secreted growth factors that have critical roles in cell fate determination and stem cell renewal. The Wnt/β-catenin pathway is initiated by binding of a Wnt protein to a Frizzled (Fzd) receptor and a coreceptor, LDL receptor-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f0ba743c4e6253836fbd805a96fcb4