Dissociation Equilibrium of Human Recombinant Interferon γ

Autor: Victoria Dorovska-Taran, Raina Boteva, Benedetto Salvato, Theodora Zlateva, Antonie J. W. G. Visser, Roumen Tsanev

Publikováno v: Biochemistry. 35:14825-14830

The biologically active form of interferon gamma is a dimer composed of two noncovalently bound identical polypeptide chains of 17 kDa each. In this study, it was found that dissociation of the dimer into monomers significantly reduced the fluorescen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6bf06832eb8d163b672066ce736c47
https://doi.org/10.1021/bi9527597

A cis-9,trans-11-conjugated linoleic acid-rich oil reduces the outcome of atherogenic process in hyperlipidemic hamster

Autor: Daniel Gripois, Karine Valeille, Jacqueline Férézou, Jean-Charles Martin, Michel Parquet, Victoria Dorovska-Taran, Annie Quignard-Boulangé, Ghislaine Amsler

Publikováno v: AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 2005, 289 (2), pp.H652-H659. ⟨10.1152/ajpheart.00130.2005⟩
American Journal of Physiology. Heart and Circulatory Physiology 2 (289), H652-H659. (2005)

Conjugated linoleic acid (CLA) mixtures demonstrated antiatherogenic properties in several animal models, including hamsters, but the mechanism of action of the main food-derived CLA isomer is unknown in this species. This study thus focused on cis-9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48bff163e3b162baa4474ba421e4b59
https://doi.org/10.1152/ajpheart.00130.2005

Comparison of the dynamic structure of alpha-chymotrypsin in aqueous solution and in reversed micelles by fluorescent active-site probing

Autor: Cees Veeger, Victoria Dorovska-Taran, Antonie J. W. G. Visser

Publikováno v: European Journal of Biochemistry, 211, 47-55
European Journal of Biochemistry 211 (1993)

A highly fluorescent anthraniloyl (Ant) group was covalently attached to the active site of alpha-chymotrypsin (CT), probably at Ser195. Ant-CT is stable at neutral pH for months, allowing a detailed fluorescence study of Ant-CT as a model protein to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0dd7139fee4208ae240474a498c538
https://research.wur.nl/en/publications/comparison-of-the-dynamic-structure-of-alpha-chymotrypsin-in-aque

Chemical enthalpy-entropy compensation effect in the hydrolysis of p-nitrophenyl carboxylates catalyzed by alkaline mesentericopeptidase

Autor: Blagoy Blagoev, Victoria Dorovska-Taran, Sava Tishkov, Diana Raykova

Publikováno v: Bioorganic Chemistry. 9:482-490

The temperature dependence of the hydrolysis of p -nitrophenyl carboxylates with general formula H(CH 2 ) n COOC 6 H 4 NO 2 catalyzed by alkaline mesentericopeptidase has been studied ( n varying from 1 to 7, temperature range 2–30°C, pH 8.80, 5 v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45c319e74ff55392843c704d4cb12f47
https://doi.org/10.1016/0045-2068(80)90008-5

Determination of the individual rate and association constants of the hydrolysis catalysed by serine proteinases by means of added nucleophiles in Eisenthal and Cornish-Bowden coordinates

Autor: Diana Raykova, Victoria Dorovska-Taran

Publikováno v: Biochimica et biophysica acta. 615(2)

It is shown that in the three-step enzyme-catalysed hydrolysis the addition of nucleophile shifts the common intersection point in Eisenthal and Cornish-Bowden coordinates when registering the second product P2. The different points obtained at diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0c5daa0ad95d3e8bf5199aba6e59a9
https://pubmed.ncbi.nlm.nih.gov/6998498