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Autor:
Alexander James, Hongjun Shi, Stuart M. Grieve, Bogdan E. Chapman, Victoria C. O׳Reilly, Richard P. Harvey, Gavin Chapman, Randall S. Johnson, Kylie Lopes Floro, Jost I. Preis, Sally L. Dunwoodie, Duncan B. Sparrow
Publikováno v:
Developmental Biology. 391(1):99-110
Mammalian embryos develop in a low oxygen environment. The transcription factor hypoxia inducible factor 1a (HIF1α) is a key element in the cellular response to hypoxia. Complete deletion of Hif1α from the mouse conceptus causes extensive placental