Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Victoria C. Garside"'
Autor:
Nicola M. Sergienko, Adam J. Trewin, Helen Kiriazis, Antonia J. A. Raaijmakers, Daniel G. Donner, Victoria C. Garside, Kelly A. Smith, James R. Bell, Kimberley M. Mellor, Lea M. D. Delbridge, Julie R. McMullen, Kate L. Weeks
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-13 (2024)
Abstract Protein phosphatase 2A (PP2A) regulatory subunit B55α has been implicated in the transcriptional regulation of cardiac growth and fibrosis by suppressing HDAC5/MEF2 signalling in cardiomyocytes. We created and characterised two mouse models
Externí odkaz:
https://doaj.org/article/962f0a0f34444cd0b5607aa60b031817
Autor:
Jeremy Lotto, Rebecca Cullum, Sibyl Drissler, Martin Arostegui, Victoria C. Garside, Bettina M. Fuglerud, Makenna Clement-Ranney, Avinash Thakur, T. Michael Underhill, Pamela A. Hoodless
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Epithelial-to-mesenchymal transitions (EMTs) of both endocardium and epicardium guide atrioventricular heart valve formation, but the cellular complexity and small scale of this tissue have restricted analyses. To circumvent these issues, we
Externí odkaz:
https://doaj.org/article/a8e5d6366264478ba5947de946bd31c2
Autor:
Gabriel M. Hauswirth, Victoria C. Garside, Lisa S. F. Wong, Heidi Bildsoe, Jan Manent, Yi-Cheng Chang, Christian M. Nefzger, Jaber Firas, Joseph Chen, Fernando J. Rossello, Jose M. Polo, Edwina McGlinn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Vertebral column length and shape exhibits remarkable robustness within a species but diversity across species. Here the authors reveal the molecular logic constraining vertebral number in mouse and a novel role for posterior Hox genes in this contex
Externí odkaz:
https://doaj.org/article/2da6dd6edf0246ddb0e84b2cc0ddcf45
Autor:
Eamon Coughlan, Victoria C. Garside, Siew Fen Lisa Wong, Huazheng Liang, Dominik Kraus, Kajari Karmakar, Upasana Maheshwari, Filippo M. Rijli, James Bourne, Edwina McGlinn
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2408-2421.e4 (2019)
Summary: Coordinated movement requires the integration of many sensory inputs including proprioception, the sense of relative body position and force associated with movement. Proprioceptive information is relayed to the cerebellum via spinocerebella
Externí odkaz:
https://doaj.org/article/217fc940a6ea405fbe77749caa8e9150
Autor:
Olivia Alder, Rebecca Cullum, Sam Lee, Arohumam C. Kan, Wei Wei, Yuyin Yi, Victoria C. Garside, Misha Bilenky, Malachi Griffith, A. Sorana Morrissy, Gordon A. Robertson, Nina Thiessen, Yongjun Zhao, Qian Chen, Duojia Pan, Steven J.M. Jones, Marco A. Marra, Pamela A. Hoodless
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 261-271 (2014)
Summary: Cell fate acquisition is heavily influenced by direct interactions between master regulators and tissue-specific enhancers. However, it remains unclear how lineage-specifying transcription factors, which are often expressed in both progenito
Externí odkaz:
https://doaj.org/article/0eaeca3af1814768b1d2f9059d4ef20c
Autor:
Gabriel M. Hauswirth, Victoria C. Garside, Lisa S. F. Wong, Heidi Bildsoe, Jan Manent, Yi-Cheng Chang, Christian M. Nefzger, Jaber Firas, Joseph Chen, Fernando J. Rossello, Jose M. Polo, Edwina McGlinn
Publikováno v:
Nature Communications
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The vertebral column of individual mammalian species often exhibits remarkable robustness in the number and identity of vertebral elements that form (known as axial formulae). The genetic mechanism(s) underlying this constraint however remain ill-def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185bc1c180d5f59b2f31e437b02087cd
https://pubmed.ncbi.nlm.nih.gov/35017475
https://pubmed.ncbi.nlm.nih.gov/35017475
Autor:
Andrew Willems, Ziyi Liu, Ee Shan Liau, Jun-An Chen, Tian Hong, Yang-Zhe Huang, Yi-Han Lee, Victoria C. Garside, Chung-Jung Li, Edwina McGlinn
Publikováno v:
Molecular Systems Biology
Molecular Systems Biology, Vol 17, Iss 4, Pp n/a-n/a (2021)
Molecular Systems Biology, Vol 17, Iss 4, Pp n/a-n/a (2021)
Positive feedback driven by transcriptional regulation has long been considered a key mechanism underlying cell lineage segregation during embryogenesis. Using the developing spinal cord as a paradigm, we found that canonical, transcription‐driven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f435b21506fbafa92e08067e1f8205
http://europepmc.org/articles/PMC8062999
http://europepmc.org/articles/PMC8062999
Autor:
Filippo M. Rijli, Huazheng Liang, Dominik Kraus, Upasana Maheshwari, Kajari Karmakar, Victoria C. Garside, James A. Bourne, Edwina McGlinn, Eamon Coughlan, Siew Fen Lisa Wong
Coordinated body movement requires the integration of many sensory inputs. This includes proprioception, the sense of relative body position and force associated with movement. Proprioceptive information is relayed to the cerebellum via spinocerebell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d6d6ca033cb002bd5a179e67eba35c
Autor:
Neil L. Bower, Bernard M. Degnan, Mathias Francois, Victoria C. Garside, Gilles Vanwalleghem, Kazu Kikuchi, Federico Gaiti, Siew Z. Tan, Edwina McGlinn, Ethan K. Scott, Emily S. W. Wong, Dawei Zheng, Benjamin M. Hogan
Publikováno v:
Science (New York, N.Y.). 370(6517)
Enhancer function, from sponges to humans Identifying the function of enhancers, DNA regions that help to regulate gene expression and evolve rapidly, has been difficult. This area of research has been hampered by the difficultly in identifying funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33e5b8f57c7fe8c2da399d94c425057
https://pubmed.ncbi.nlm.nih.gov/33154124
https://pubmed.ncbi.nlm.nih.gov/33154124
Autor:
Yongjun Zhao, Gordon Robertson, Wei Wei, Steven J.M. Jones, Arohumam C. Kan, Duojia Pan, Sam Lee, Malachi Griffith, Qian Chen, Marco A. Marra, Victoria C. Garside, A. Sorana Morrissy, Rebecca L. Cullum, Pamela A. Hoodless, Misha Bilenky, Yuyin Yi, Nina Thiessen, Olivia Alder
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 261-271 (2014)
Summary: Cell fate acquisition is heavily influenced by direct interactions between master regulators and tissue-specific enhancers. However, it remains unclear how lineage-specifying transcription factors, which are often expressed in both progenito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51258f5d6995375f80871fa56552b30d
https://doi.org/10.1016/j.celrep.2014.08.046
https://doi.org/10.1016/j.celrep.2014.08.046