Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Victoria Bunik"'
Autor:
Victoria Bunik
Publikováno v:
Biology, Vol 12, Iss 7, p 897 (2023)
Understanding the molecular mechanisms of neurological disorders is necessary for the development of personalized medicine. When the diagnosis considers not only the disease symptoms, but also their molecular basis, treatments tailored to individual
Externí odkaz:
https://doaj.org/article/fe99b33d357f45048d7c1974ecfa1723
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Both hypoxia and inhibition of 2-oxoglutarate dehydrogenase complex (OGDHC) are known to change cellular amino acid pools, but the quantitative comparison of the metabolic and physiological outcomes has not been done. We hypothesize that OGDHC inhibi
Externí odkaz:
https://doaj.org/article/1722bab8c5eb44a0b07cc83c1e390da3
Autor:
Alexandra Boyko, Polina Tsepkova, Vasily Aleshin, Artem Artiukhov, Garik Mkrtchyan, Alexander Ksenofontov, Lyudmila Baratova, Sergey Ryabov, Anastasia Graf, Victoria Bunik
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Our study aims at developing knowledge-based strategies minimizing chronic changes in the brain after severe spinal cord injury (SCI). The SCI-induced long-term metabolic alterations and their reactivity to treatments shortly after the injury are cha
Externí odkaz:
https://doaj.org/article/3cc14fb5153b49ddad3b171eed08c130
Autor:
Roberto Contestabile, Martino Luigi di Salvo, Victoria Bunik, Angela Tramonti, Fiammetta Vernì
Publikováno v:
Open Biology, Vol 10, Iss 3 (2020)
A perturbed uptake of micronutrients, such as minerals and vitamins, impacts on different human diseases, including cancer and neurological disorders. Several data converge towards a crucial role played by many micronutrients in genome integrity main
Externí odkaz:
https://doaj.org/article/3902a06c081a49d09f6b0f72605c3de8
Autor:
Lev Zavileyskiy, Victoria Bunik
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 327 (2022)
A transcription factor p53 is activated upon cellular exposure to endogenous and exogenous stresses, triggering either homeostatic correction or cell death. Depending on the stress level, often measurable as DNA damage, the dual outcome is supported
Externí odkaz:
https://doaj.org/article/8a4895f2ab564f35a051792a4d0c6eb4
Publikováno v:
Cells, Vol 9, Iss 1, p 139 (2020)
Function of brain amino acids as neurotransmitters or their precursors implies changes in the amino acid levels and/or metabolism in response to physiological and environmental challenges. Modelling such challenges by pregnancy and/or hypoxia, we cha
Externí odkaz:
https://doaj.org/article/9b8cd50a8bfb4773a25d5e1eca2972ac
Autor:
Alexandra Boyko, Alexander Ksenofontov, Sergey Ryabov, Lyudmila Baratova, Anastasia Graf, Victoria Bunik
Publikováno v:
Frontiers in Medicine, Vol 4 (2018)
Severe spinal cord injuries (SCIs) result in chronic neuroinflammation in the brain, associated with the development of cognitive and behavioral impairments. Nitric oxide (NO•) is a gaseous messenger involved in neuronal signaling and inflammation,
Externí odkaz:
https://doaj.org/article/e90eff95b2cf4840bc2688d27222ee43
Publikováno v:
Biology, Vol 5, Iss 4, p 53 (2016)
Glutamate dehydrogenase (GDH) of animal cells is usually considered to be a mitochondrial enzyme. However, this enzyme has recently been reported to be also present in nucleus, endoplasmic reticulum and lysosomes. These extramitochondrial localizatio
Externí odkaz:
https://doaj.org/article/699a0e6322da4600adf6253391e34975
Autor:
Victoria Bunik
Understanding molecular mechanisms of neurological disorders is required for development of personalized medicine. When the diagnosis considers not only the disease symptoms, but also their molecular basis, the treatments tailored for individual pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2ead06c622e57e4619a4caaf1437450
https://doi.org/10.20944/preprints202304.0973.v1
https://doi.org/10.20944/preprints202304.0973.v1
Autor:
Victoria Bunik, Vasily Aleshin, Isabel Nogues, Thilo Kähne, Alessia Parroni, Roberto Contestabile, Martino Luigi Di Salvo, Anastasia Graf, Angela Tramonti
Publikováno v:
Journal of neurochemistry (2022). doi:10.1111/jnc.15576
info:cnr-pdr/source/autori:Bunik, Victoria; Aleshin, Vasily; Nogues, Isabel; Kähne, Thilo; Parroni, Alessia; Contestabile, Roberto; Salvo, Martino Luigi; Graf, Anastasia; Tramonti, Angela/titolo:Thiamine-dependent regulation of mammalian brain pyridoxal kinase in vitro and in vivo/doi:10.1111%2Fjnc.15576/rivista:Journal of neurochemistry/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Bunik, Victoria; Aleshin, Vasily; Nogues, Isabel; Kähne, Thilo; Parroni, Alessia; Contestabile, Roberto; Salvo, Martino Luigi; Graf, Anastasia; Tramonti, Angela/titolo:Thiamine-dependent regulation of mammalian brain pyridoxal kinase in vitro and in vivo/doi:10.1111%2Fjnc.15576/rivista:Journal of neurochemistry/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume
Vitamins B (thiamine) and B (pyridox (al/ine/amine)) are crucial for central nervous system (CNS) function and neurogenesis due to the coenzyme action of their phosphorylated derivatives in the brain metabolism of glucose and neurotransmitters. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7475bb261fcf2422eb542463f6b7850b
https://pubmed.ncbi.nlm.nih.gov/35050500
https://pubmed.ncbi.nlm.nih.gov/35050500